There are 6 ways to get from Chicago to Myrtle Beach by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Chicago Midway International Airport
best- Fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR)plane MDW - MYR
3h 41m$104–509Fly from Chicago O'Hare International Airport
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane ORD - MYR
4h 9m$68–319Bus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus Greyhound US0100
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus Greyhound US0641S
25h 45m$180–297Train, bus
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
29h 15m$629–974Drive 882.8 mi
- Drive from Chicago to Myrtle Beachcar 882.8 mi
17h 3m$151–218Bus via Columbus
- Take the bus from Chicago to Columbusbus
- Take the bus from Columbus to Charlottebus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
25h 45m$112–232
Chicago to Myrtle Beach by bus
Comparing Your Travel Options
The cheapest way to get from Chicago to Myrtle Beach is to fly which costs $65 - $320 and takes 4h 9m.
The fastest way to get from Chicago to Myrtle Beach is to fly which takes 3h 41m and costs $100 - $550.
No, there is no direct bus from Chicago station to Myrtle Beach station. However, there are services departing from Chicago Bus Station and arriving at Myrtle Beach Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 25h 45m.
The distance between Chicago and Myrtle Beach is 756 miles. The road distance is 888 miles.
The best way to get from Chicago to Myrtle Beach without a car is to bus which takes 25h 45m and costs $180 - $300.
It takes approximately 3h 41m to get from Chicago to Myrtle Beach, including transfers.
Chicago to Myrtle Beach bus services, operated by Greyhound USA, depart from Chicago Bus Station.
The best way to get from Chicago to Myrtle Beach is to fly which takes 3h 41m and costs $100 - $550. Alternatively, you can bus, which costs $180 - $300 and takes 25h 45m.
Chicago to Myrtle Beach bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Myrtle Beach is 1h ahead of Chicago. It is currently 9:34 AM in Chicago and 10:34 AM in Myrtle Beach.
What companies run services between Chicago, IL, USA and Myrtle Beach, SC, USA?
Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) twice daily. Alternatively, you can take a bus from Chicago Bus Station to Myrtle Beach Bus Station via Atlanta Bus Station in around 25h 45m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Myrtle Beach
- Ave. Duration
- 2h 18m
- When
- Every day
- Estimated price
- $55–300
Flights from Chicago O'Hare International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $55–300
- Website
- southwest.com
Flights from Chicago Midway International Airport to Myrtle Beach
- Ave. Duration
- 2h
- When
- Saturday
- Estimated price
- $90–490
Flights from Chicago Midway International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 3h 55m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
- Website
- delta.com
Flights from Chicago Midway International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Chicago O'Hare International Airport to Myrtle Beach
- Ave. Duration
- 2h 33m
- When
- Every day
- Estimated price
- $55–300
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $500–800
- Website
- Amtrak
Train from Petersburg Amtrak Station to Fayetteville Amtrak Station
- Ave. Duration
- 2h 54m
- Frequency
- Twice daily
- Estimated price
- $100–160
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- Every 4 hours
- Estimated price
- $130–200
- Website
- Greyhound
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Twice daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Fayetteville Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Website
- Greyhound
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- $14–22
- Website
- Greyhound
Bus from Camden to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $21–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h
- Frequency
- 5 times a day
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Chicago to Columbus
- Ave. Duration
- 7h 30m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- Barons Bus
Bus from Columbus to Charlotte
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $45–100
- Website
- Barons Bus
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Yes, the driving distance between Chicago to Myrtle Beach is 888 miles. It takes approximately 17h 3m to drive from Chicago to Myrtle Beach.
Book your Chicago to Myrtle Beach bus tickets online with Omio and FlixBus.
There are 5621+ hotels available in Myrtle Beach.










