There are 7 ways to get from Chicago to Myrtle Beach by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago Midway International Airport to Myrtle Beach
best- Fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR)plane MDW - MYR
3h 33m$92–468Bus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus FlixBus 2512 / ...
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus Greyhound US0641
24h 5m$125–214Train, bus via Petersburg
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Wilmington Cape Fear Public Transitbus
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
30h 45m$255–465Drive 882.2 mi
- Drive from Chicago to Myrtle Beachcar 882.2 mi
17h 4m$161–233Fly Chicago O'Hare International Airport to Myrtle Beach
- Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane ORD - MYR
4h 4m$108–288Fly Chicago O'Hare International Airport to Wilmington International Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Wilmington International Airport (ILM)plane ORD - ILM
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
6h 28m$152–444Train, bus
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Wilsontrain
- Take the bus from Wilson to Wilmington Amtrak Stationbus
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
33h 19m
Chicago to Myrtle Beach by bus
Questions & Answers
The cheapest way to get from Chicago to Myrtle Beach is to bus which costs $120 - $220 and takes 24h 5m.
The fastest way to get from Chicago to Myrtle Beach is to fly which takes 3h 33m and costs $90 - $470.
No, there is no direct bus from Chicago station to Myrtle Beach station. However, there are services departing from Chicago Bus Station and arriving at Myrtle Beach Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 24h 5m.
The distance between Chicago and Myrtle Beach is 755 miles. The road distance is 887.4 miles.
The best way to get from Chicago to Myrtle Beach without a car is to bus which takes 24h 5m and costs $120 - $220.
It takes approximately 3h 33m to get from Chicago to Myrtle Beach, including transfers.
Chicago to Myrtle Beach bus services, operated by Flixbus USA, depart from Chicago Bus Station.
The best way to get from Chicago to Myrtle Beach is to fly which takes 3h 33m and costs $90 - $470. Alternatively, you can bus, which costs $120 - $220 and takes 24h 5m.
Chicago to Myrtle Beach bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Myrtle Beach is 1h ahead of Chicago. It is currently 1:40 AM in Chicago and 2:40 AM in Myrtle Beach.
What companies run services between Chicago, IL, USA and Myrtle Beach, SC, USA?
Southwest Airlines flies from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) once daily. Alternatively, you can take a bus from Chicago Bus Station to Myrtle Beach Bus Station via Atlanta Bus Station in around 24h 5m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Myrtle Beach
- Ave. Duration
- 2h 11m
- When
- Saturday
- Estimated price
- $55–310
Flights from Chicago O'Hare International Airport to Wilmington International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $70–390
Flights from Chicago O'Hare International Airport to Wilmington International Airport via Charlotte
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $70–390
Flights from Chicago O'Hare International Airport to Wilmington International Airport via Reagan Washington
- Ave. Duration
- 4h 23m
- When
- Saturday and Sunday
- Estimated price
- $80–420
- Website
- southwest.com
Flights from Chicago Midway International Airport to Myrtle Beach
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $80–450
Flights from Chicago Midway International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 4h 22m
- When
- Saturday
- Estimated price
- $90–470
Flights from Chicago O'Hare International Airport to Myrtle Beach
- Ave. Duration
- 2h 10m
- When
- Saturday
- Estimated price
- $55–310
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Wilmington International Airport via Atlanta
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $85–430
- Website
- united.com
Flights from Chicago O'Hare International Airport to Myrtle Beach
- Ave. Duration
- 2h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $55–310
Flights from Chicago O'Hare International Airport to Wilmington International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $70–390
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 20h 56m
- Frequency
- Once daily
- Estimated price
- $160–300
- Website
- https://www.amtrak.com/home.html
Train from Petersburg Amtrak Station to Fayetteville Amtrak Station
- Ave. Duration
- 2h 54m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 23h 56m
- Frequency
- Once daily
- Estimated price
- $120–300
- Website
- https://www.amtrak.com/home.html
Train from Raleigh Union Station to Wilson
- Ave. Duration
- 1h 1m
- Frequency
- Once daily
- Estimated price
- $8–10
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- 3 times a day
- Estimated price
- $80–150
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 25m
- Frequency
- 4 times a day
- Estimated price
- $75–140
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $45–65
- Website
- https://www.greyhound.com/
Bus from Fayetteville Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $15–21
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Wilson to Wilmington Amtrak Station
- Ave. Duration
- 3h 47m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Chicago to Myrtle Beach is 887 miles. It takes approximately 17h 4m to drive from Chicago to Myrtle Beach.
Book your Chicago to Myrtle Beach bus tickets online with Omio and FlixBus.
There are 5840+ hotels available in Myrtle Beach.






