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How to get fromChicago to Myrtle Beachby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

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There are 8 ways to get from Chicago to Myrtle Beach by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR)plane plane MDW - MYR
    3h 41m
    $94–459

  2. Fly from Chicago O'Hare International Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane plane ORD - MYR
    4h 10m
    $74–339

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0641S
    25h 45m
    $162–290

  4. Train, bus via Wilson

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Wilsontrain train
    3. Take the bus from Wilson to Wilmington Amtrak Stationbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    30h 20m
    $318–673

  5. Drive  882.1 mi

    1. Drive from Chicago to Myrtle Beachcar car 882.1 mi
    17h 6m
    $161–233

  6. Bus via Columbus

    1. Take the bus from Chicago to N Wilson Rd & Ferrell Pl - Columbusbus bus
    2. Take the bus from Columbus to Charlottebus bus
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    25h 45m
    $107–231

  7. Train, bus

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    31h 41m
    $351–773

  8. Train, bus #2

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to Selma Stationtrain train
    3. Take the train from Selma Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    38h 5m
    $367–788

Chicago to Myrtle Beach by bus

Calendar7Weekly Buses
Duration25h 45mAverage Duration
Ticket$162Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Myrtle Beach.ExpandLaunch map view
  • Distance: 751.9 mi
  • Duration: 3h 41m

What companies run services between Chicago, IL, USA and Myrtle Beach, SC, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) twice daily. Alternatively, you can take a bus from Chicago Bus Station to Myrtle Beach Bus Station via Atlanta Bus Station in around 25h 45m.

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