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How to get fromChicago to Myrtle Beachby plane, bus (Greyhound, Flixbus), train, bus, or car

Find Transport to Myrtle Beach

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There are 7 ways to get from Chicago to Myrtle Beach by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR)plane plane MDW - MYR
    3h 38m
    $108–569
  2. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0641
    25h 45m
    $156–348
  3. Train, bus via Wilson

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Wilsontrain train
    3. Take the bus from Wilson to Wilmington Amtrak Stationbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    30h 20m
    $342–721
  4. Drive 882.2 mi

    1. Drive from Chicago to Myrtle Beachcar car 882.2 mi
    17h 4m
    $161–233
  5. Fly from Chicago O'Hare International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane plane ORD - MYR
    4h 13m
    $204–569
  6. Train, bus

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    31h 26m
    $376–821
  7. Train, bus #2

    1. Take the train from Chicago Union Station to Raleigh Union Stationtrain train Floridian
    2. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0645S
    35h 19m
    $379–798

Chicago to Myrtle Beach by bus

Calendar7Weekly Buses
Duration25h 45mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Myrtle Beach, SC, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) 3 times a day. Alternatively, you can take a bus from Chicago Bus Station to Myrtle Beach Bus Station via Atlanta Bus Station in around 25h 45m.

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