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How to get fromChicago to Muscatineby train, car, bus, taxi or plane

Find Transport to Muscatine

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There are 6 ways to get from Chicago to Muscatine by train, car, bus, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, drive (Amtrak)

    best
    1. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train Southwest Chief / ...
    2. Drive from Galesburg Amtrak Station to Muscatinecar car
    4h 20m
    $39–97
  2. Drive 199.6 mi

    cheapest
    1. Drive from Chicago to Muscatinecar car 199.6 mi
    3h 34m
    $37–53
  3. Bus, taxi

    1. Take the bus from Chicago Bus Station to Moline Center Stationbus bus Greyhound US0155S / ...
    2. Take the taxi from Moline Center Station to Muscatinetaxi taxi
    5h 3m
    $99–149
  4. Fly to Quad City International Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane plane ORD - MLI
    2. Take the taxi from Moline-Airport-MLI to Muscatinetaxi taxi
    3h 41m
    $108–345
  5. Fly to The Eastern Iowa Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to The Eastern Iowa Airport (CID)plane plane ORD - CID
    2. Drive from Cedar-Rapids-Airport-CID to Muscatinecar car
    4h 14m
    $48–281
  6. Fly to Burlington Municipal Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane plane ORD - BRL
    2. Take the taxi from Burlington Municipal Airport (BRL) to Muscatinetaxi taxi
    4h 17m
    $162–265

Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI) flights

Calendar41Weekly Planes
Duration1h 13mAverage Duration
Ticket$33Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Muscatine, IA, USA?

There is no direct connection from Chicago to Muscatine. However, you can take the train to Galesburg Amtrak Station then drive to Muscatine. Alternatively, you can take the bus to Moline Center Station then take the taxi to Muscatine.

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