There are 7 ways to get from Chicago to Murrells Inlet by plane, bus (Greyhound, Flixbus), train, car, bus (Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Chicago Midway International Airport
best- Fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR)plane MDW - MYR
3h 50m$128–505Fly from Chicago O'Hare International Airport
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane ORD - MYR
4h 19m$98–365Bus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus Greyhound US0100
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus Greyhound US0641S
26h 6m$217–342Train, drive (Amtrak)
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Kingstree Stationtrain
- Drive from Kingstree Station to Murrells Inletcar
29h 19m$682–1,055Drive 890.8 mi
- Drive from Chicago to Murrells Inletcar 890.8 mi
17h 17m$163–235Bus via Columbus
- Take the bus from Chicago to Columbusbus
- Take the bus from Columbus to Charlottebus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
26h 6m$150–281Train, bus
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
29h 21m$668–1,023
Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) flights
Comparing Your Travel Options
The cheapest way to get from Chicago to Murrells Inlet is to drive which costs $160 - $240 and takes 17h 17m.
The fastest way to get from Chicago to Murrells Inlet is to fly which takes 3h 50m and costs $120 - $550.
No, there is no direct bus from Chicago station to Murrells Inlet station. However, there are services departing from Chicago Bus Station and arriving at Myrtle Beach Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 26h 6m.
The distance between Chicago and Murrells Inlet is 767 miles. The road distance is 896 miles.
The best way to get from Chicago to Murrells Inlet without a car is to bus which takes 26h 6m and costs $210 - $350.
It takes approximately 3h 50m to get from Chicago to Murrells Inlet, including transfers.
Chicago to Murrells Inlet bus services, operated by Greyhound USA, depart from Chicago Bus Station.
The best way to get from Chicago to Murrells Inlet is to fly which takes 3h 50m and costs $120 - $550. Alternatively, you can bus, which costs $210 - $350 and takes 26h 6m.
Chicago to Murrells Inlet bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Murrells Inlet is 1h ahead of Chicago. It is currently 6:42 AM in Chicago and 7:42 AM in Murrells Inlet.
What companies run services between Chicago, IL, USA and Murrells Inlet, SC, USA?
Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) 4 times a day. Alternatively, you can take a bus from Chicago Bus Station to Murrells Inlet via Atlanta Bus Station and Myrtle Beach Bus Station in around 26h 6m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Myrtle Beach
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $85–450
Flights from Chicago Midway International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 4h 25m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $90–480
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Myrtle Beach
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $55–310
Flights from Chicago O'Hare International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $55–310
- Website
- delta.com
Flights from Chicago Midway International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $95–490
Flights from Chicago O'Hare International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $65–330
- Website
- united.com
Flights from Chicago O'Hare International Airport to Myrtle Beach
- Ave. Duration
- 2h 21m
- When
- Monday to Saturday
- Estimated price
- $55–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $500–800
- Website
- Amtrak
Train from Petersburg Amtrak Station to Kingstree Station
- Ave. Duration
- 5h 46m
- Frequency
- Twice daily
- Estimated price
- $170–270
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $500–800
- Website
- Amtrak
Train from Petersburg Amtrak Station to Fayetteville Amtrak Station
- Ave. Duration
- 2h 54m
- Frequency
- Twice daily
- Estimated price
- $100–160
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- 4 times a day
- Estimated price
- $120–190
- Website
- Greyhound
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Camden to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Fayetteville Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 15h 40m
- Frequency
- Twice daily
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Chicago to Columbus
- Ave. Duration
- 7h 30m
- Frequency
- Twice daily
- Estimated price
- $30–75
- Website
- Barons Bus
Bus from Columbus to Charlotte
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $45–100
- Website
- Barons Bus
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Chicago to Murrells Inlet is 896 miles. It takes approximately 17h 17m to drive from Chicago to Murrells Inlet.
There are 3262+ hotels available in Murrells Inlet.










