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How to get fromChicago to Murrells Inletby plane, bus (Greyhound, Flixbus), train, car, bus (Greyhound), or bus

Find Transport to Murrells Inlet

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There are 8 ways to get from Chicago to Murrells Inlet by plane, bus (Greyhound, Flixbus), train, car, bus (Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR)plane plane MDW - MYR
    3h 55m
    $128–505

  2. Fly from Chicago O'Hare International Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane plane ORD - MYR
    4h 25m
    $102–385

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0641S
    26h 6m
    $203–323

  4. Train, drive (Amtrak)

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Kingstree Stationtrain train
    3. Drive from Kingstree Station to Murrells Inletcar car
    29h 19m
    $329–718

  5. Drive  890.2 mi

    1. Drive from Chicago to Murrells Inletcar car 890.2 mi
    17h 19m
    $163–235

  6. Bus via Columbus

    1. Take the bus from Chicago to N Wilson Rd & Ferrell Pl - Columbusbus bus
    2. Take the bus from Columbus to Charlottebus bus
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    26h 6m
    $147–279

  7. Train, bus via Petersburg

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Wilsontrain train
    3. Take the bus from Wilson to Wilmington Amtrak Stationbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    30h 41m
    $354–715

  8. Train, bus

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to Selma Stationtrain train
    3. Take the train from Selma Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    38h 26m
    $404–824

Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) flights

Calendar18Weekly Planes
Duration3h 18mAverage Duration
Ticket$85Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Murrells Inlet.ExpandLaunch map view
  • Distance: 762.1 mi
  • Duration: 3h 55m

What companies run services between Chicago, IL, USA and Murrells Inlet, SC, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) 3 times a day. Alternatively, you can take a bus from Chicago Bus Station to Murrells Inlet via Atlanta Bus Station and Myrtle Beach Bus Station in around 26h 6m.

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