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How to get fromChicago to Mobileby plane, bus (Greyhound), train (Amtrak), car, bus, taxi, or train

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There are 11 ways to get from Chicago to Mobile by plane, bus (Greyhound), train (Amtrak), car, bus, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Mobile Regional Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Mobile Regional Airport (MOB)plane plane MDW - MOB
    9h 12m
    $122–605

  2. Fly Chicago O'Hare International Airport to Mobile Regional Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Mobile Regional Airport (MOB)plane plane ORD - MOB
    9h 6m
    $82–415

  3. Bus (Greyhound)

    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Montgomery Intermodal Centerbus bus
    3. Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus bus
    22h 29m
    $158–312

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train City of New Orleans
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train Amtrak Mardi Gras Service / ...
    23h 25m
    $297–660

  5. Drive 857.3 mi

    1. Drive from Chicago to Mobilecar car 857.3 mi
    15h 42m
    $157–226

  6. Fly Chicago Midway International Airport to Pensacola International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Pensacola International Airport (PNS)plane plane MDW - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    7h 28m
    $122–625

  7. Fly Chicago O'Hare International Airport to Pensacola International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Pensacola International Airport (PNS)plane plane ORD - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    8h
    $108–465

  8. Fly Chicago O'Hare International Airport to Destin–Fort Walton Beach Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Destin–Fort Walton Beach Airport (VPS)plane plane ORD - VPS
    2. Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus bus
    7h 6m
    $212–655

  9. Fly Chicago Midway International Airport to Northwest Florida Beaches International Airport, taxi, bus

    1. Fly from Chicago Midway International Airport (MDW) to Northwest Florida Beaches International Airport (ECP)plane plane MDW - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Whataburger - Defuniak Springstaxi taxi
    3. Take the bus from Whataburger - Defuniak Springs to Love's Travel Stop - Loxleybus bus
    7h 22m
    $318–945

  10. Fly Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Chicago Midway International Airport (MDW) to Birmingham–Shuttlesworth International Airport (BHM)plane plane MDW - BHM
    2. Drive from Birmingham-Airport-BHM to Mobilecar car
    7h 31m
    $198–975

  11. Fly Chicago Midway International Airport to Louis Armstrong New Orleans International Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Louis Armstrong New Orleans International Airport (MSY)plane plane MDW - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    8h 55m
    $136–650

Chicago to Mobile by bus (Greyhound)

Calendar7Weekly Buses
Duration22h 29mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Mobile, AL, USA?

Delta and Southwest Airlines fly from Chicago Midway International Airport (MDW) to Mobile Regional Airport (MOB) 5 times a day. Alternatively, you can take a bus from Chicago Bus Station to Water NB at St Louis St via Indianapolis Union Station, Montgomery Intermodal Center, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 22h 29m.

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