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How to get fromChicago to Mobileby plane, bus (Greyhound), train (Amtrak), car, or bus

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There are 7 ways to get from Chicago to Mobile by plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Mobile Regional Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Mobile Regional Airport (MOB)plane plane MDW - MOB
    5h 52m
    $132–595

  2. Fly Chicago O'Hare International Airport to Pensacola International Airport, bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Pensacola International Airport (PNS)plane plane ORD - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    7h 46m
    $66–310

  3. Bus (Greyhound)

    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Montgomery Intermodal Centerbus bus
    3. Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus bus
    22h 16m
    $149–239

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train City of New Orleans
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train Amtrak Mardi Gras Service / ...
    23h 25m
    $271–610

  5. Drive  857.3 mi

    1. Drive from Chicago to Mobilecar car 857.3 mi
    15h 42m
    $157–226

  6. Fly Chicago O'Hare International Airport to Mobile Regional Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Mobile Regional Airport (MOB)plane plane ORD - MOB
    6h 18m
    $108–435

  7. Fly Chicago Midway International Airport to Pensacola International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Pensacola International Airport (PNS)plane plane MDW - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    9h 1m
    $86–430

Chicago to Mobile by bus (Greyhound)

Calendar7Weekly Buses
Duration22h 16mAverage Duration
Ticket$149Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Mobile.ExpandLaunch map view
  • Distance: 792.4 mi
  • Duration: 5h 52m

What companies run services between Chicago, IL, USA and Mobile, AL, USA?

Delta and Southwest Airlines fly from Chicago Midway International Airport (MDW) to Mobile Regional Airport (MOB) 5 times a day. Alternatively, you can take a bus from Chicago Bus Station to Govt EB Mid Block Past Joachim St via Indianapolis Union Station, Montgomery Intermodal Center, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 22h 16m.

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