• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 7 ways to get from Chicago to Mississippi by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Chicago O'Hare to Memphis  •  3 h 31 min

  1. Fly from Chicago O'Hare (ORD) to Memphis (MEM) ORD - MEM

$118 - $445

Cheapest option

Bus  •  14 h 45 min

  1. Take the bus from Chicago, Il to Memphis, Tn 1227 / ...
  2. Take the bus from Memphis, Tn to Jackson, Ms 1209

$80 - $197

5 alternative options

Fly Chicago Midway to Memphis  •  3 h 20 min

  1. Fly from Chicago Midway (MDW) to Memphis (MEM) MDW - MEM

$128 - $624

Fly Chicago O'Hare to Jackson/Vicksburg  •  4 h 8 min

  1. Fly from Chicago O'Hare (ORD) to Jackson/Vicksburg (JAN) ORD - JAN

$347 - $600

Fly Chicago O'Hare to Meridian  •  3 h 59 min

  1. Fly from Chicago O'Hare (ORD) to Meridian (MEI) ORD - MEI

$159 - $725

Train  •  15 h 7 min

  1. Take the train from Chicago Union Station to Jackson Amtrak Station City Of New Orleans

$100 - $290

Drive  •  12 h 3 min

  1. Drive from Chicago to Jackson 743.6 miles

$70 - $110

Questions & Answers

The cheapest way to get from Chicago to Mississippi is to drive which costs $70 - $110 and takes 12 h 3 min.

More details

The quickest way to get from Chicago to Mississippi is to fly which costs $120 - $650 and takes 3 h 20 min.

More details

No, there is no direct bus from Chicago to Mississippi. However, there are services departing from Chicago, Il and arriving at Jackson, Ms via Memphis, Tn. The journey, including transfers, takes approximately 14 h 45 min.

More details

Yes, there is a direct train departing from Chicago Union Station station and arriving at Jackson Amtrak Station station. Services depart once daily, and operate every day. The journey takes approximately 15 h 7 min.

More details

The distance between Chicago and Mississippi is 630 miles. The road distance is 743.6 miles.

Get driving directions

The best way to get from Chicago to Mississippi without a car is to bus which takes 14 h 45 min and costs $80 - $200.

More details

It takes approximately 3 h 31 min to get from Chicago to Mississippi, including transfers.

More details

Chicago to Mississippi bus services, operated by Greyhound USA, depart from Chicago, Il station.

More details

Chicago to Mississippi train services, operated by Amtrak, arrive at Chicago Union Station.

More details

The best way to get from Chicago to Mississippi is to fly which takes 3 h 31 min and costs $110 - $450. Alternatively, you can bus, which costs $80 - $200 and takes 14 h 45 min, you could also train, which costs $100 - $290 and takes 15 h 7 min.

Mode details

Map of how to get from Chicago to Mississippi.
Launch map view
  • Distance: 629.6 miles
  • Duration: 3 h 31 min

What companies run services between Chicago, IL, USA and Mississippi, USA?

American Airlines and United Airlines fly from Chicago to Southaven every 3 hours. Alternatively, you can take a bus from Chicago to Jackson via Memphis, Tn in around 14 h 45 min.

Airlines
American Airlines
Website
aa.com
Flights from Chicago O'Hare to Memphis
Ave. Duration
1 h 43 min
When
Every day
Estimated price
$210 - $600
Flights from Chicago O'Hare to Jackson/Vicksburg via Charlotte
Ave. Duration
5 h
When
Every day
Estimated price
$380 - $1,000
Flights from Chicago O'Hare to Jackson/Vicksburg via Dallas/Ft.Worth
Ave. Duration
5 h
When
Every day
Estimated price
$380 - $1,000
Flights from Chicago O'Hare to Meridian
Ave. Duration
2 h 10 min
When
Every day
Estimated price
$140 - $700
United Airlines
Website
united.com
Flights from Chicago O'Hare to Memphis
Ave. Duration
1 h 57 min
When
Every day
Estimated price
$210 - $600
Flights from Chicago O'Hare to Jackson/Vicksburg
Ave. Duration
2 h 11 min
When
Every day
Estimated price
$330 - $900
Flights from Chicago O'Hare to Jackson/Vicksburg via Houston
Ave. Duration
5 h 4 min
When
Every day
Estimated price
$330 - $900
Delta
Website
delta.com
Flights from Chicago Midway to Memphis via Atlanta
Ave. Duration
4 h 12 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $800
Flights from Chicago O'Hare to Jackson/Vicksburg via Atlanta
Ave. Duration
4 h 47 min
When
Every day
Estimated price
$350 - $950
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to Memphis
Ave. Duration
1 h 41 min
When
Every day
Estimated price
$260 - $800
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Chicago Union Station to Jackson Amtrak Station
Ave. Duration
15 h 7 min
Frequency
Once daily
Estimated price
$100 - $290
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$180 - $260
Business Coach Seat
$210 - $290
Room
$420 - $600
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Chicago, Il to Memphis, Tn
Ave. Duration
9 h 50 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
greyhound.com
Economy
$50 - $90
Flexible
$100 - $140
Bus from Memphis, Tn to Jackson, Ms
Ave. Duration
3 h 55 min
Frequency
Once daily
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Chicago O'Hare Airport to Memphis Airport is the direct flight which takes 1 h 39 min.

Search flights

Chicago to Mississippi bus services, operated by Greyhound USA, arrive at Jackson, Ms station.

More details

Chicago to Mississippi train services, operated by Amtrak, arrive at Jackson Amtrak Station.

More details

Yes, the driving distance between Chicago to Mississippi is 744 miles. It takes approximately 12 h 3 min to drive from Chicago to Mississippi.

Get driving directions

American Airlines and United Airlines offer flights from Chicago O'Hare Airport to Memphis Airport.

Search flights

Book your Chicago to Mississippi train tickets online with Rome2rio.

Search and book

Book your Chicago to Mississippi bus tickets online with Greyhound and Greyhound.

Search and book

There are four+ hotels available in Mississippi. Prices start at $100 USD per night.

More details

The best way to get from Chicago to Chicago O'Hare Airport is to subway which takes 42 min and costs $2 - $5.

More details