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How to get fromChicago to Mexicaliby plane, bus, train, bus (Flixbus, Greyhound), or car

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There are 12 ways to get from Chicago to Mexicali by plane, bus, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Yuma International Airport, bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Yuma International Airport (YUM)plane plane ORD - YUM
    2. Take the bus from San Luis Río Colorado to Mexicalibus bus
    11h 40m
    $2,273–10,608

  2. Train, bus via Flagstaff

    1. Take the train from Chicago Union Station to Flagstafftrain train
    2. Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus bus
    3. Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Calexico Bus Stationbus bus
    41h 43m
    $8,756–18,887

  3. Bus

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Phoenix Bus Stationbus bus
    3. Take the bus from Phoenix Bus Station to Calexico Bus Stationbus bus
    43h 19m
    $5,532–10,622

  4. Drive  3,111.4 km

    1. Drive from Chicago to Mexicalicar car 3,111.4 km
    34h 6m
    $6,185–8,934

  5. Fly Chicago Midway International Airport to San Diego International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN)plane plane MDW - SAN
    2. Take the bus from Tijuana to Mexicalibus bus
    10h 22m
    $3,484–14,098

  6. Fly Chicago O'Hare International Airport to San Diego International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to San Diego International Airport (SAN)plane plane ORD - SAN
    2. Take the bus from Tijuana to Mexicalibus bus
    10h 47m
    $2,684–10,598

  7. Fly Chicago Midway International Airport to Imperial County Airport

    1. Fly from Chicago Midway International Airport (MDW) to Imperial County Airport (IPL)plane plane MDW - IPL
    8h 31m
    $3,904–17,183

  8. Fly Chicago Midway International Airport to Phoenix, bus

    1. Fly from Chicago Midway International Airport (MDW) to Phoenix (PHX)plane plane MDW - PHX
    2. Take the bus from Phoenix Bus Station to Calexico Bus Stationbus bus
    11h 41m
    $2,859–5,403

  9. Fly Chicago O'Hare International Airport to Phoenix, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Phoenix (PHX)plane plane ORD - PHX
    2. Take the bus from Phoenix Bus Station to Calexico Bus Stationbus bus
    12h 3m
    $3,959–7,903

  10. Fly Chicago O'Hare International Airport to Palm Springs International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Palm Springs International Airport (PSP)plane plane ORD - PSP
    2. Take the bus from Indio Bus Station to Calexico Bus Stationbus bus
    13h 53m
    $3,425–7,129

  11. Fly Chicago Midway International Airport to Yuma International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Yuma International Airport (YUM)plane plane MDW - YUM
    2. Take the bus from San Luis Río Colorado to Mexicalibus bus
    11h 31m
    $3,073–14,108

  12. Train, bus

    1. Take the train from Chicago Union Station to Yuma Amtraktrain train
    2. Take the bus from 3rd Street @ Gila Street to William Brook Ave @ B Streetbus bus 95
    3. Take the bus from San Luis Río Colorado to Mexicalibus bus
    2d 15h
    $11,500–26,110

Chicago to Mexicali by train, bus, and foot

Calendar3Weekly Services
Duration2d 15hAverage Duration
Ticket$11,500Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Mexicali.ExpandLaunch map view
  • Distance: 2,706.7 km
  • Duration: 11h 40m

What companies run services between Chicago, IL, USA and Mexicali, Mexico?

You can take a bus from Chicago Bus Station to Central de Autobuses de Mexicali via St Louis Bus Station, Phoenix Bus Station, Calexico Bus Station, and C. José Azueta y Blvr. López Mateos in around 43h 19m. Alternatively, Southwest Airlines and Southern Airways Express fly from Chicago Midway International Airport (MDW) to Imperial County Airport (IPL) 5 times a week.

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Want to know more about travelling around Mexico

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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