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How to get fromChicago to Mexicaliby plane, bus, bus (Flixbus, Greyhound), train or car

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There are 11 ways to get from Chicago to Mexicali by plane, bus, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Yuma International Airport, bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Yuma International Airport (YUM)plane plane ORD - YUM
    2. Take the bus from San Luis Río Colorado to Mexicalibus bus
    11h 43m
    $1,857–9,556

  2. Bus

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Phoenix Bus Stationbus bus
    3. Take the bus from Phoenix Bus Station to Calexico Bus Stationbus bus
    43h 8m
    $3,212–9,087

  3. Train, bus via San Bernardino

    1. Take the train from Chicago Union Station to San Bernardinotrain train Southwest Chief
    2. Take the bus from San Bernardino to Calexico Bus Stationbus bus FlixBus 2055
    47h 31m
    $4,272–9,820

  4. Drive 3,111.4 km

    1. Drive from Chicago to Mexicalicar car 3,111.4 km
    34h 7m
    $6,054–8,744

  5. Fly Chicago O'Hare International Airport to San Diego International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to San Diego International Airport (SAN)plane plane ORD - SAN
    2. Take the bus from Tijuana to Mexicalibus bus
    11h
    $3,483–15,086

  6. Fly Chicago Midway International Airport to San Diego International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN)plane plane MDW - SAN
    2. Take the bus from Tijuana to Mexicalibus bus
    10h 43m
    $4,983–21,086

  7. Fly Chicago Midway International Airport to Imperial County Airport

    1. Fly from Chicago Midway International Airport (MDW) to Imperial County Airport (IPL)plane plane MDW - IPL
    8h 38m
    $3,403–15,181

  8. Fly Chicago Midway International Airport to Phoenix, bus

    1. Fly from Chicago Midway International Airport (MDW) to Phoenix (PHX)plane plane MDW - PHX
    2. Take the bus from Phoenix Bus Station to Calexico Bus Stationbus bus
    11h 32m
    $3,708–16,101

  9. Fly Chicago O'Hare International Airport to Phoenix, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Phoenix (PHX)plane plane ORD - PHX
    2. Take the bus from Phoenix Bus Station to Calexico Bus Stationbus bus
    11h 51m
    $5,608–12,101

  10. Fly Chicago Midway International Airport to Yuma International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Yuma International Airport (YUM)plane plane MDW - YUM
    2. Take the bus from San Luis Río Colorado to Mexicalibus bus
    11h 17m
    $2,757–13,556

  11. Train, bus

    1. Take the train from Chicago Union Station to Yuma Amtraktrain train
    2. Take the bus from 3rd Street @ Gila Street to William Brook Ave @ B Streetbus bus 95
    3. Take the bus from San Luis Río Colorado to Mexicalibus bus
    2d 16h
    $3,335–10,822

Chicago to Mexicali by train, bus, and foot

Calendar3Weekly Services
Duration2d 16hAverage Duration
Ticket$3,335Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Mexicali, Mexico?

You can take a bus from Chicago Bus Station to Central de Autobuses de Mexicali via St Louis Bus Station, Phoenix Bus Station, Calexico Bus Station, and C. José Azueta y Blvr. López Mateos in around 43h 8m. Alternatively, Southwest Airlines and Southern Airways Express fly from Chicago Midway International Airport (MDW) to Imperial County Airport (IPL) 6 times a week.

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