There are 5 ways to get from Chicago to Manlius by plane, train (Amtrak), bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Chicago O'Hare International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR)plane ORD - SYR
4h 9m$198–725Bus (Greyhound)
cheapest- Take the bus from Chicago Bus Station to Cleveland Bus Stationbus Greyhound US0164
- Take the bus from Cleveland Bus Station to Syracuse Bus Stationbus Greyhound US0171
17h 27m$121–246Train (Amtrak)
- Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain Lake Shore Limited
13h 19m$263–499Drive 686.3 mi
- Drive from Chicago to Manliuscar 686.3 mi
11h 47m$126–181Fly from Chicago Midway International Airport
- Fly from Chicago Midway International Airport (MDW) to Syracuse Hancock International Airport (SYR)plane MDW - SYR
5h 22m$238–975
Chicago to Manlius by bus (Greyhound)
Questions & Answers
The cheapest way to get from Chicago to Manlius is to bus which costs $120 - $250 and takes 17h 27m.
The fastest way to get from Chicago to Manlius is to fly which takes 4h 9m and costs $190 - $750.
No, there is no direct bus from Chicago station to Manlius. However, there are services departing from Chicago Bus Station and arriving at Fayette St & W Seneca St via Cleveland Bus Station, Regional Transportation Center and A2. The journey, including transfers, takes approximately 17h 27m.
The distance between Chicago and Manlius is 643 miles. The road distance is 690.3 miles.
The best way to get from Chicago to Manlius without a car is to train which takes 13h 19m and costs $260 - $500.
It takes approximately 4h 9m to get from Chicago to Manlius, including transfers.
Chicago to Manlius bus services, operated by Greyhound USA, depart from Chicago Bus Station.
The best way to get from Chicago to Manlius is to fly which takes 4h 9m and costs $190 - $750. Alternatively, you can train, which costs $260 - $500 and takes 13h 19m, you could also bus, which costs $120 - $250 and takes 17h 27m.
Chicago to Manlius bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Manlius is 1h ahead of Chicago. It is currently 4:44 AM in Chicago and 5:44 AM in Manlius.
What companies run services between Chicago, IL, USA and Manlius, NY, USA?
American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR) hourly. Alternatively, Amtrak operates a train from Chicago Union Station to Syracuse Regional Transportation Center twice daily. Tickets cost $180–410 and the journey takes 12h 58m.
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport via Detroit
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $100–600
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 4h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Chicago Midway International Airport to Syracuse Hancock International Airport via Detroit
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $140–850
Flights from Chicago Midway International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $190–1,000
- Website
- united.com
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $100–600
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport via Washington Dulles
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $130–700
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $100–600
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport via Reagan Washington
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $130–700
Flights from Chicago Midway International Airport to Syracuse Hancock International Airport via Reagan Washington
- Ave. Duration
- 4h 29m
- When
- Monday to Saturday
- Estimated price
- $180–1,000
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Syracuse Regional Transportation Center
- Ave. Duration
- 12h 58m
- Frequency
- Twice daily
- Estimated price
- $180–410
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Syracuse Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Yes, the driving distance between Chicago to Manlius is 690 miles. It takes approximately 11h 47m to drive from Chicago to Manlius.
There are 87+ hotels available in Manlius.





