There are 8 ways to get from Chicago to Lawrence by plane, car, train (Amtrak), bus (Flixbus, Greyhound), subway, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Manhattan Regional Airport, drive
best- Fly from Chicago O'Hare International Airport (ORD) to Manhattan Regional Airport (MHK)ORD - MHK
- Drive from Manhattan Regional Airport (MHK) to Lawrence
5h 14m$68–339Train (Amtrak)
- Take the train from Chicago Union Station to Lawrence Amtrak StationSouthwest Chief
9h$75–200Bus
- Take the bus from Chicago Bus Station to St Louis Bus StationFlixBus N2521 / ...
- Take the bus from St Louis Bus Station to Lawrence Bus StopGreyhound US0136
12h 50m$84–181Drive 545.6 mi
- Drive from Chicago to Lawrence545.6 mi
9h 11m$100–144Subway to Chicago Midway International Airport, fly to Kansas City, bus
- Take the subway from Roosevelt to Midway
- Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)MDW - MCI
- Take the bus from Kansas City Bus Station to Lawrence Bus Stop
6h 24m$98–521Fly Chicago O'Hare International Airport to Kansas City, bus
- Fly from Chicago O'Hare International Airport (ORD) to Kansas City (MCI)ORD - MCI
- Take the bus from Kansas City Bus Station to Lawrence Bus Stop
6h 55m$152–621Train to General Mitchell International Airport, fly to Kansas City, bus
- Take the train from Chicago Union Station to Milwaukee
- Fly from General Mitchell International Airport (MKE) to Kansas City (MCI)MKE - MCI
- Take the bus from Kansas City Bus Station to Lawrence Bus Stop
8h 1m$314–785Fly Chicago O'Hare International Airport to Kirksville Regional Airport, train
- Fly from Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK)ORD - IRK
- Take the train from La Plata Station to Lawrence Amtrak Station
8h 29m$116–310
Chicago to Lawrence by train (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Lawrence is to bus which costs $80 - $190 and takes 12h 50m.
The fastest way to get from Chicago to Lawrence is to fly and drive which takes 5h 14m and costs $65 - $340.
No, there is no direct bus from Chicago station to Lawrence. However, there are services departing from Chicago Bus Station and arriving at Lawrence Bus Stop via St Louis Bus Station. The journey, including transfers, takes approximately 12h 50m.
Yes, there is a direct train departing from Chicago Union Station station and arriving at Lawrence Amtrak Station station. Services depart twice daily, and operate every day. The journey takes approximately 9h.
The distance between Chicago and Lawrence is 610 miles. The road distance is 548.8 miles.
The best way to get from Chicago to Lawrence without a car is to train which takes 9h and costs $75 - $200.
It takes approximately 5h 14m to get from Chicago to Lawrence, including transfers.
Chicago to Lawrence bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Lawrence train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Lawrence is to train which takes 9h and costs $75 - $200. Alternatively, you can bus, which costs $80 - $190 and takes 12h 50m.
What companies run services between Chicago, IL, USA and Lawrence, KS, USA?
Amtrak operates a train from Chicago Union Station to Lawrence Amtrak Station twice daily. Tickets cost $75–200 and the journey takes 9h. Alternatively, you can take a bus from Chicago Bus Station to Lawrence Bus Stop via St Louis Bus Station in around 12h 50m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Kansas City
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $85–500
Flights from Chicago Midway International Airport to Kansas City via St. Louis
- Ave. Duration
- 3h 10m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $90–550
Flights from General Mitchell International Airport to Kansas City
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $120–750
Flights from General Mitchell International Airport to Kansas City via Chicago Midway International Airport
- Ave. Duration
- 3h 57m
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–800
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Manhattan Regional Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $50–310
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $70–420
- Website
- united.com
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $70–420
Flights from General Mitchell International Airport to Kansas City via Chicago O'Hare International Airport
- Ave. Duration
- 3h 54m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–800
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Kirksville Regional Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $60–170
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Lawrence Amtrak Station
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $75–200
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Website
- https://www.amtrak.com/home.html
Train from La Plata Station to Lawrence Amtrak Station
- Ave. Duration
- 4h 6m
- Frequency
- Twice daily
- Estimated price
- $23–90
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $25–50
- Coach Seat short notice purchase
- $23–90
- Business - advance purchase
- $30–160
- Business Class
- $50–230
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Roosevelt to Midway
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–95
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Lawrence Bus Stop
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Kansas City Bus Station to Lawrence Bus Stop
- Ave. Duration
- 45 min
- Frequency
- 3 times a day
- Estimated price
- $10–16
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Chicago to Lawrence bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Chicago to Lawrence train services, operated by Amtrak, arrive at Lawrence Amtrak Station.
Yes, the driving distance between Chicago to Lawrence is 549 miles. It takes approximately 9h 11m to drive from Chicago to Lawrence.
Book your Chicago to Lawrence train tickets online with Omio.
Book your Chicago to Lawrence bus tickets online with Omio and FlixBus.
There are 38+ hotels available in Lawrence.















