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How to get fromChicago to Kentuckyby bus (Greyhound, Amtrak, Flixbus), train, bus, car, plane, bus (Amtrak), or subway

Find Transport to Kentucky

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There are 10 ways to get from Chicago to Kentucky by bus (Greyhound, Amtrak, Flixbus), train, bus, car, plane, bus (Amtrak), or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    6h 5m
    $40–75

  2. Train, bus via Indianapolis

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    7h 44m
    $73–157

  3. Drive  293.6 mi

    1. Drive from Chicago to Louisvillecar car 293.6 mi
    5h 4m
    $54–78

  4. Fly Chicago O'Hare International Airport to Covington

    1. Fly from Chicago O'Hare International Airport (ORD) to Covington (CVG)plane plane ORD - CVG
    3h 53m
    $154–807

  5. Train, bus

    1. Take the train from Van Buren St. to Gary Metro Centertrain train Ssl / ...
    2. Take the bus from Gary Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    7h 6m
    $48–79

  6. Bus via Lafayette (Amtrak)

    1. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus Chicago
    2. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus Chicago
    7h 35m
    $54–94

  7. Subway to Chicago Midway International Airport, fly to Covington

    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Covington (CVG)plane plane MDW - CVG
    3h 39m
    $154–367

  8. Subway to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    4h 4m
    $94–658

  9. Fly Chicago O'Hare International Airport to Louisville International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    4h 30m
    $74–468

  10. Fly Chicago O'Hare International Airport to Blue Grass Airport, line 3 bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Take the bus from Transit Center to Centre Parkway @ 1349bus bus
    5h 35m
    $44–287

Chicago to Kentucky by bus

Calendar54Weekly Buses
Duration6h 5mAverage Duration
Ticket$40Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Kentucky.ExpandLaunch map view
  • Distance: 298.3 mi
  • Duration: 6h 5m

What companies run services between Chicago, IL, USA and Kentucky, USA?

Greyhound USA operates a bus from Chicago Bus Station to Louisville Bus Station 4 times a day. Tickets cost $45–75 and the journey takes 6h 5m. Two other operators also service this route. Alternatively, American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Covington (CVG) hourly.

Airlines
Train operators
Bus operators

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