Rome2Rio

How to get fromChicago to KAPEby train, taxi, bus, car, plane, or bus (Flixbus, Greyhound)

Find Transport to KAPE

See all options

There are 9 ways to get from Chicago to KAPE by train, taxi, bus, car, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, taxi

    best
    1. Take the train from Chicago Union Station to Carbondaletrain train Saluki / ...
    2. Take the taxi from Carbondale to KAPEtaxi taxi
    6h 32m
    $188–320

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    9h 3m
    $68–116

  3. Bus, taxi

    1. Take the bus from Chicago to Anna - Shellbus bus Chicago
    2. Take the taxi from Anna - Shell to KAPEtaxi taxi
    7h 46m
    $150–188

  4. Drive 373.3 mi

    1. Drive from Chicago to KAPEcar car 373.3 mi
    6h 20m
    $69–99

  5. Fly Chicago O'Hare International Airport to Williamson County Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to KAPEtaxi taxi
    4h 21m
    $212–375

  6. Train, bus

    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    7h 54m
    $103–217

  7. Fly Chicago O'Hare International Airport to Barkley Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to KAPEtaxi taxi
    4h 47m
    $188–485

  8. Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 36m
    $98–552

  9. Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 59m
    $298–752

Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA) flights

Calendar14Weekly Planes
Duration1h 22mAverage Duration
Ticket$44Cheapest Price
See schedules

Questions & Answers

Map of how to get from Chicago to KAPE.ExpandLaunch map view
  • Distance: 356.6 mi
  • Duration: 6h 32m

What companies run services between Chicago, IL, USA and KAPE, MO, USA?

You can take a bus from Chicago Bus Station to KAPE via St Louis Bus Station and Cape Girardeau in around 9h 3m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound