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There are 9 ways to get from Chicago to Jacksonville by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Chicago Midway to Jacksonville

  1. Fly from Chicago Midway (MDW) to Jacksonville (OAJ)

8 alternative options

Fly Chicago O'Hare to Wilmington, bus

  1. Fly from Chicago O'Hare (ORD) to Wilmington (ILM)
  2. Take the bus from Wilmington to Jacksonville

Fly Chicago Midway to Myrtle Beach, bus

  1. Fly from Chicago Midway (MDW) to Myrtle Beach (MYR)
  2. Take the bus from Myrtle Beach to Jacksonville

Fly Chicago O'Hare to Myrtle Beach, bus

  1. Fly from Chicago O'Hare (ORD) to Myrtle Beach (MYR)
  2. Take the bus from Myrtle Beach to Jacksonville

Train, bus via Rockville

  1. Take the train from Chicago Union Station to Rockville Amtrak
  2. Take the train from Washington Union Station to Wilson
  3. Take the bus from Wilson to Jacksonville

Bus

  1. Take the bus from Chicago to Toledo
  2. Take the bus from Toledo to Winston Salem
  3. Take the bus from Winston Salem to Raleigh
  4. Take the bus from Raleigh to Jacksonville

Bus via Atlanta

  1. Take the bus from Chicago IL to Atlanta GA
  2. Take the bus from Atlanta to Myrtle Beach, SC
  3. Take the bus from Myrtle Beach to Jacksonville

Train, bus

  1. Take the train from Chicago Union Station to Alexandria
  2. Take the train from Alexandria to Wilson
  3. Take the bus from Wilson to Jacksonville Amtrak Bus Stop

Drive

  1. Drive from Chicago to Jacksonville

Chicago to Jacksonville by train, subway and bus

The journey time between Chicago and Jacksonville is around 26h 47m and covers a distance of around 1134 miles. This includes an average layover time of around 2h 6m. Operated by Amtrak, Washington Metropolitan Area Transit Authority and Greyhound USA, the Chicago to Jacksonville service departs from Chicago Union Station and arrives in Jacksonville. Typically seven services run weekly, although weekend and holiday schedules can vary so check in advance.

7 Weekly Services
26h 47m Average Duration
$140 Cheapest Price
See schedules
Chicago → Jacksonville
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Rules to follow in United States

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Travel within United States

Nationwide control measures in place

COVID-19 help in United States

If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 800-232-4636

Frequently Asked Questions


Yes, travel within United States is currently allowed.

Explore travel options

Domestic travel is not restricted, but some conditions may apply

  • Face masks are recommended
  • There is a social distancing requirement of 2 metres
  • Nationwide control measures in place

Explore travel options

The national COVID-19 helpline number in Jacksonville is 800-232-4636.

Wearing a face mask on public transport in Jacksonville is recommended.

The social distance requirement in Jacksonville is 2 metres.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.

Last updated: 3 Aug 2022
Exceptions may apply, for full details: Centers for Disease control and prevention (CDC).

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Chicago to Jacksonville is to fly and bus which costs $120 - $260 and takes 8h 19m.

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The quickest way to get from Chicago to Jacksonville is to fly and bus which costs $250 - $650 and takes 6h 1m.

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No, there is no direct bus from Chicago to Jacksonville. However, there are services departing from Chicago and arriving at Jacksonville via Toledo, Winston Salem and Raleigh. The journey, including transfers, takes approximately 27h 15m.

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The distance between Chicago and Jacksonville is 743 miles. The road distance is 926.4 miles.

Get driving directions

The best way to get from Chicago to Jacksonville without a car is to train and bus via Rockville which takes 26h 47m and costs $140 - $210.

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It takes approximately 6h 8m to get from Chicago to Jacksonville, including transfers.

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Chicago to Jacksonville bus services, operated by Barons Bus, depart from Chicago station.

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The best way to get from Chicago to Jacksonville is to fly which takes 6h 8m and costs $110 - $370. Alternatively, you can bus, which costs $120 - $210 and takes 27h 15m.

Mode details

There is no direct flight from Chicago Midway Airport to Jacksonville Airport. The quickest flight takes 6h 20m and has one stopover.

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Chicago to Jacksonville bus services, operated by Greyhound USA, arrive at Jacksonville station.

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Map of how to get from Chicago to Jacksonville.
Launch map view
  • Distance: 743.4 miles
  • Duration: 6h 8m

What companies run services between Chicago, IL, USA and Jacksonville, NC, USA?

Delta, Southwest Airlines and three other airlines fly from Chicago to Jacksonville hourly. Alternatively, you can take a bus from Chicago to Jacksonville via Toledo, Winston Salem, and Raleigh in around 27h 15m.

Airlines
American Airlines
Website
aa.com
Flights from Chicago Midway to Jacksonville via Charlotte
Ave. Duration
4h 50m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$110 - $360
Flights from Chicago O'Hare to Wilmington
Ave. Duration
2h 13m
When
Every day
Estimated price
$200 - $700
Flights from Chicago O'Hare to Wilmington via Charlotte
Ave. Duration
4h 27m
When
Every day
Estimated price
$200 - $700
Flights from Chicago O'Hare to Wilmington via Reagan Washington
Ave. Duration
4h 32m
When
Saturday
Estimated price
$210 - $700
Flights from Chicago O'Hare to Wilmington via New York La Guardia
Ave. Duration
4h 47m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $750
Flights from Chicago O'Hare to Wilmington via Philadelphia
Ave. Duration
4h 48m
When
Every day
Estimated price
$210 - $750
Flights from Chicago O'Hare to Myrtle Beach
Ave. Duration
2h 8m
When
Every day
Estimated price
$170 - $380
Flights from Chicago O'Hare to Myrtle Beach via Charlotte
Ave. Duration
4h 2m
When
Every day
Estimated price
$170 - $380
Flights from Chicago O'Hare to Myrtle Beach via Reagan Washington
Ave. Duration
4h 11m
When
Every day
Estimated price
$170 - $380
Flights from Chicago O'Hare to Myrtle Beach via Philadelphia
Ave. Duration
5h 2m
When
Monday to Saturday
Estimated price
$170 - $380
Delta
Website
delta.com
Flights from Chicago Midway to Jacksonville via Atlanta
Ave. Duration
5h 10m
When
Every day
Estimated price
$150 - $410
Flights from Chicago Midway to Jacksonville via Detroit, Atlanta
Ave. Duration
7h 51m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $500
Flights from Chicago O'Hare to Wilmington via Atlanta
Ave. Duration
4h 44m
When
Every day
Estimated price
$230 - $600
Flights from Chicago O'Hare to Wilmington via New York La Guardia
Ave. Duration
5h 14m
When
Monday to Friday
Estimated price
$260 - $600
Flights from Chicago Midway to Myrtle Beach via Atlanta
Ave. Duration
4h 43m
When
Every day
Estimated price
$160 - $410
Flights from Chicago O'Hare to Myrtle Beach via Atlanta
Ave. Duration
5h 4m
When
Every day
Estimated price
$150 - $370
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to Myrtle Beach
Ave. Duration
1h 56m
When
Every day
Estimated price
$190 - $205
Flights from Chicago Midway to Myrtle Beach via Nashville
Ave. Duration
4h 21m
When
Every day
Estimated price
$190 - $205
Flights from Chicago Midway to Myrtle Beach via Baltimore
Ave. Duration
4h 10m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $205
Flights from Chicago O'Hare to Myrtle Beach via Baltimore
Ave. Duration
4h 52m
When
Every day
Estimated price
$110 - $330
United Airlines
Website
united.com
Flights from Chicago O'Hare to Wilmington via Newark
Ave. Duration
5h 5m
When
Every day
Estimated price
$210 - $700
Flights from Chicago O'Hare to Myrtle Beach
Ave. Duration
2h 10m
When
Every day
Estimated price
$170 - $210
Flights from Chicago O'Hare to Myrtle Beach via Washington Dulles
Ave. Duration
4h 24m
When
Saturday and Sunday
Estimated price
$170 - $210
Spirit Airlines
Website
spirit.com
Flights from Chicago O'Hare to Myrtle Beach
Ave. Duration
2h 8m
When
Every day
Estimated price
$90 - $220
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 800-872-7245
Website
amtrak.com
Train from Chicago Union Station to Rockville Amtrak
Ave. Duration
16h 36m
Frequency
Once daily
Estimated price
$80 - $120
Website
Amtrak
Coach Seat
$80 - $120
Premium
$290 - $400
Flexi Coach Seat
$160 - $240
Business Seat
$170 - $240
Train from Washington Union Station to Wilson
Ave. Duration
4h 50m
Frequency
Twice daily
Estimated price
$40 - $60
Website
Amtrak
Coach Seat
$40 - $60
Premium
$210 - $300
Flexi Coach Seat
$70 - $110
Business Seat
$70 - $100
Train from Chicago Union Station to Alexandria
Ave. Duration
23h 32m
Frequency
6 times a week
Estimated price
$90 - $130
Website
Amtrak
Coach Seat
$90 - $130
Premium
$310 - $430
Flexi Coach Seat
$180 - $280
Business Seat
$200 - $280
Train from Alexandria to Wilson
Ave. Duration
4h 31m
Frequency
Twice daily
Estimated price
$40 - $60
Website
Amtrak
Coach Seat
$40 - $60
Premium
$210 - $290
Flexi Coach Seat
$65 - $100
Business Seat
$70 - $100
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Wilmington to Jacksonville
Ave. Duration
1h 5m
Frequency
Once daily
Estimated price
$12 - $18
Website
greyhound.com
Economy
$12 - $18
Flexible
$29 - $45
Bus from Myrtle Beach to Jacksonville
Ave. Duration
3h 25m
Frequency
Once daily
Estimated price
$20 - $28
Website
greyhound.com
Economy
$20 - $28
Flexible
$35 - $60
Bus from Wilson to Jacksonville
Ave. Duration
2h 35m
Frequency
Once daily
Estimated price
$17 - $25
Website
greyhound.com
Economy
$17 - $25
Flexible
$35 - $55
Bus from Chicago to Toledo
Ave. Duration
5h 20m
Frequency
Once daily
Estimated price
$30 - $45
Website
greyhound.com
Economy
$30 - $45
Flexible
$50 - $80
Bus from Toledo to Winston Salem
Ave. Duration
13h 15m
Frequency
Once daily
Estimated price
$55 - $85
Website
greyhound.com
Economy
$55 - $85
Flexible
$90 - $130
Bus from Winston Salem to Raleigh
Ave. Duration
1h 55m
Frequency
Twice daily
Estimated price
$17 - $25
Website
greyhound.com
Economy
$17 - $25
Flexible
$35 - $55
Bus from Raleigh to Jacksonville
Ave. Duration
3h 35m
Frequency
Once daily
Estimated price
$22 - $35
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $60
Palmland Bus Lines
Website
palmlandlines.com
Bus from Chicago IL to Atlanta GA
Ave. Duration
14h 40m
Frequency
Hourly
Estimated price
$60 - $80
Schedules at
palmlandlines.com
Southeastern Stages
Phone
+1 404-591-2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Atlanta to Myrtle Beach, SC
Ave. Duration
7h 45m
Frequency
Once daily
Estimated price
$35 - $100
Schedules at
southeasternstages.com
Child 2-15
$35 - $85
Senior
$45 - $65
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 800-872-7245
Website
amtrak.com
Bus from Wilson to Jacksonville Amtrak Bus Stop
Ave. Duration
2h 37m
Frequency
Once daily
Website
Amtrak

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Jacksonville is 1h ahead of Chicago. It is currently 5:21 AM in Chicago and 6:21 AM in Jacksonville.

Yes, the driving distance between Chicago to Jacksonville is 926 miles. It takes approximately 16h 1m to drive from Chicago to Jacksonville.

Get driving directions

Frontier Airlines, American Airlines, Southwest Airlines and Delta offer flights from Chicago Midway Airport to Jacksonville Airport.

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There are 29+ hotels available in Jacksonville. Prices start at $100 USD per night.

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The best way to get from Chicago to Chicago Midway Airport is to subway which takes 24 min and costs $1 - $5.

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