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How to get fromChicago to Ithacaby plane, bus, train, bus (Greyhound, Flixbus) or car

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There are 9 ways to get from Chicago to Ithaca by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Syracuse Hancock International Airport, bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR)planeORD - SYR
    2. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    6h 20m
    $112–610

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus
    2. Take the bus from Cleveland, OH to Buffalo, NYbus
    3. Take the bus from Buffalo to Ithacabus
    16h 5m
    $82–194

  3. Train, bus

    1. Take the train from Chicago Union Station to RochestertrainLake Shore Limited
    2. Take the bus from Rochester to IthacabusAdt N823 / ...
    14h 20m
    $105–256

  4. Drive 658 mi

    1. Drive from Chicago to Ithacacar658 mi
    11h 35m
    $121–174

  5. Fly Chicago O'Hare International Airport to Rochester, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)planeORD - ROC
    2. Take the bus from Rochester, NY to Ithaca, NYbus
    6h 59m
    $152–525

  6. Fly Chicago Midway International Airport to Rochester, bus

    1. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)planeMDW - ROC
    2. Take the bus from Rochester, NY to Ithaca, NYbus
    6h 37m
    $108–565

  7. Fly Chicago O'Hare International Airport to Wilkes-Barre/Scranton International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Wilkes-Barre/Scranton International Airport (AVP)planeORD - AVP
    2. Take the bus from Scranton, Pa to Ithacabus
    7h 25m
    $114–435

  8. Fly Chicago O'Hare International Airport to Buffalo Niagara International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)planeORD - BUF
    2. Take the bus from Buffalo Niagara International Airport to Ithacabus
    7h 46m
    $182–960

  9. Fly Chicago Midway International Airport to Buffalo Niagara International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)planeMDW - BUF
    2. Take the bus from Buffalo Niagara International Airport to Ithacabus
    7h 22m
    $212–1,160

Chicago to Ithaca by train and bus

Calendar14Weekly Services
Duration14h 20mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Ithaca, NY, USA?

You can take a bus from Chicago Bus Station to Ithaca via Cleveland Bus Station, Cleveland, OH, Buffalo, NY, and Buffalo in around 16h 5m.

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