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How to get fromChicago to Isle of Palmsby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus or taxi

Find Transport to Isle of Palms

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There are 7 ways to get from Chicago to Isle of Palms by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)planeMDW - CHS
    3h 58m
    $92–452

  2. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus StationbusFlixBus 2512 / ...
    2. Take the bus from Atlanta to Charleston Amtrak StationbusAtlanta
    24h 19m
    $140–333

  3. Train via Petersburg (Amtrak)

    1. Take the train from Chicago Union Station to Petersburg Amtrak StationtrainFloridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak StationtrainSilver Meteor / ...
    28h 45m
    $178–483

  4. Drive 879.7 mi

    1. Drive from Chicago to Isle of Palmscar879.7 mi
    16h 1m
    $161–232

  5. Fly from Chicago O'Hare International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)planeORD - CHS
    4h 26m
    $92–372

  6. Bus, taxi

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus
    2. Take the bus from Atlanta to Summervillebus
    3. Take the taxi from Summerville to Isle of Palmstaxi
    25h 28m
    $170–333

  7. Train (Amtrak)

    1. Take the train from Chicago Union Station to Savannah StationtrainFloridian
    2. Take the train from Savannah Station to Charleston Amtrak StationtrainPalmetto / ...
    34h 28m
    $362–1,381

Chicago Midway International Airport (MDW) to Charleston International Airport (CHS) flights

Calendar27Weekly Planes
Duration4h 11mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Isle of Palms, SC, USA?

Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS) 4 times a day. Alternatively, you can take a bus from Chicago Bus Station to Isle of Palms via Atlanta Bus Station, Atlanta, and Charleston Amtrak Station in around 24h 19m.

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Need to know: Greyhound

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