There are 7 ways to get from Chicago to Iowa by plane, bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Des Moines
best- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
3h 19m$100–576Fly Chicago O'Hare International Airport to Quad City International Airport, line 10 bus
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane ORD - MLI
- Take the bus from Centre Station to Districtbus
4h 21m$32–227Bus (Greyhound)
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0155S
8h 30m$68–121Drive 330 mi
- Drive from Chicago to Des Moinescar 330 mi
5h 32m$61–87Fly Chicago Midway International Airport to Des Moines
- Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane MDW - DSM
3h 2m$140–826Fly Chicago O'Hare International Airport to Waterloo Municipal Airport
- Fly from Chicago O'Hare International Airport (ORD) to Waterloo Municipal Airport (ALO)plane ORD - ALO
3h 17m$50–266Fly Chicago Midway International Airport to Omaha
- Fly from Chicago Midway International Airport (MDW) to Omaha (OMA)plane MDW - OMA
3h 17m$188–1,035
Chicago O'Hare International Airport (ORD) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Chicago to Iowa is to drive which costs $60 - $90 and takes 5h 32m.
The fastest way to get from Chicago to Iowa is to fly which takes 3h 2m and costs $140 - $850.
The distance between Chicago and Iowa is 324 miles. The road distance is 332 miles.
The best way to get from Chicago to Iowa without a car is to bus which takes 8h 30m and costs $65 - $130.
It takes approximately 3h 19m to get from Chicago to Iowa, including transfers.
The best way to get from Chicago to Iowa is to fly which takes 3h 19m and costs $95 - $600. Alternatively, you can bus, which costs $65 - $130 and takes 8h 30m.
Yes, the driving distance between Chicago to Iowa is 332 miles. It takes approximately 5h 32m to drive from Chicago to Iowa.
There are 524+ hotels available in Iowa.
What companies run services between Chicago, IL, USA and Iowa, USA?
American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) hourly. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Des Moines once daily. Tickets cost $60–110 and the journey takes 8h 25m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Des Moines
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $120–800
Flights from Chicago Midway International Airport to Omaha
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $160–1,000
Flights from Chicago Midway International Airport to Omaha via St. Louis
- Ave. Duration
- 3h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $190–1,200
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $80–550
Flights from Chicago O'Hare International Airport to Waterloo Municipal Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $30–240
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $28–220
- Website
- united.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–550
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $28–220
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $60–110
- Website
- https://www.greyhound.com/
- Phone
- +1 309-788-3360
- Website
- metroqc.com
Bus from Centre Station to District
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- https://www.metroqc.com
- Adult Cash Fare
- $1
Want to know more about travelling around United States
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