There are 7 ways to get from Chicago to Iowa by plane, bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Des Moines
best- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
3h 23m$100–576Fly Chicago O'Hare International Airport to Quad City International Airport, line 10 bus
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane ORD - MLI
- Take the bus from Centre Station to Districtbus
4h 26m$34–257Bus (Greyhound)
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
6h 39m$52–114Drive 330 mi
- Drive from Chicago to Des Moinescar 330 mi
5h 32m$61–87Fly Chicago O'Hare International Airport to Waterloo Municipal Airport
- Fly from Chicago O'Hare International Airport (ORD) to Waterloo Municipal Airport (ALO)plane ORD - ALO
3h 11m$54–296Fly Chicago Midway International Airport to Omaha
- Fly from Chicago Midway International Airport (MDW) to Omaha (OMA)plane MDW - OMA
3h 17m$138–735Fly Chicago O'Hare International Airport to The Eastern Iowa Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to The Eastern Iowa Airport (CID)plane ORD - CID
- Take the bus from GTC Bay 9 to Court St Transportation Centerbus
5h 59m
Chicago O'Hare International Airport (ORD) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Chicago to Iowa is to drive which costs $60 - $90 and takes 5h 32m.
The fastest way to get from Chicago to Iowa is to fly which takes 3h 11m and costs $50 - $300.
The distance between Chicago and Iowa is 324 miles. The road distance is 332 miles.
The best way to get from Chicago to Iowa without a car is to bus which takes 6h 39m and costs $50 - $120.
It takes approximately 3h 23m to get from Chicago to Iowa, including transfers.
The best way to get from Chicago to Iowa is to fly which takes 3h 23m and costs $95 - $600. Alternatively, you can bus, which costs $50 - $120 and takes 6h 39m.
Yes, the driving distance between Chicago to Iowa is 332 miles. It takes approximately 5h 32m to drive from Chicago to Iowa.
There are 200+ hotels available in Iowa.
What companies run services between Chicago, IL, USA and Iowa, USA?
American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 4 hours. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Des Moines 3 times a day. Tickets cost $40–110 and the journey takes 6h 34m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–550
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $30–250
Flights from Chicago O'Hare International Airport to The Eastern Iowa Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $35–260
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $80–550
Flights from Chicago O'Hare International Airport to Waterloo Municipal Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $35–270
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $30–250
Flights from Chicago O'Hare International Airport to The Eastern Iowa Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $35–260
- Website
- southwest.com
Flights from Chicago Midway International Airport to Omaha
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $110–700
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $40–110
- Website
- https://www.greyhound.com/
- Phone
- +1 309-788-3360
- Website
- metroqc.com
Bus from Centre Station to District
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- https://www.metroqc.com
- Adult Cash Fare
- $1
- Phone
- +1-319-362-0375
- Website
- 380express.com
Bus from GTC Bay 9 to Court St Transportation Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Website
- https://www.380express.com
- Schedules at
- https://www.380express.com/schedule/
Want to know more about travelling around United States
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