Rome2Rio

How to get fromChicago to Iowaby plane, bus (Greyhound), car or bus

Find Transport to Iowa

See all options

There are 7 ways to get from Chicago to Iowa by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Des Moines

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane plane ORD - DSM
    3h 23m
    $100–576
  2. Fly Chicago O'Hare International Airport to Quad City International Airport, line 10 bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane plane ORD - MLI
    2. Take the bus from Centre Station to Districtbus bus
    4h 26m
    $34–257
  3. Bus (Greyhound)

    1. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    6h 39m
    $52–114
  4. Drive 330 mi

    1. Drive from Chicago to Des Moinescar car 330 mi
    5h 32m
    $61–87
  5. Fly Chicago O'Hare International Airport to Waterloo Municipal Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Waterloo Municipal Airport (ALO)plane plane ORD - ALO
    3h 11m
    $54–296
  6. Fly Chicago Midway International Airport to Omaha

    1. Fly from Chicago Midway International Airport (MDW) to Omaha (OMA)plane plane MDW - OMA
    3h 17m
    $138–735
  7. Fly Chicago O'Hare International Airport to The Eastern Iowa Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to The Eastern Iowa Airport (CID)plane plane ORD - CID
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    5h 59m

Chicago O'Hare International Airport (ORD) to Des Moines (DSM) flights

Calendar50Weekly Planes
Duration1h 32mAverage Duration
Ticket$82Cheapest Price
See schedules

Questions & Answers

What companies run services between Chicago, IL, USA and Iowa, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 4 hours. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Des Moines 3 times a day. Tickets cost $40–110 and the journey takes 6h 34m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound