There are 9 ways to get from Chicago to Iowa by plane, bus (Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Des Moines
best- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)ORD - DSM
3h 23m$100–526Fly Chicago O'Hare International Airport to Quad City International Airport, line 10 bus
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)ORD - MLI
- Take the bus from Centre Station to District
4h 20m$40–257Bus via Des Moines (Greyhound)
- Take the bus from Chicago Bus Station to Des MoinesGreyhound US0123 / ...
6h 38m$54–109Drive 330 mi
- Drive from Chicago to Des Moines330 mi
5h 29m$61–87Fly Chicago O'Hare International Airport to Waterloo Municipal Airport
- Fly from Chicago O'Hare International Airport (ORD) to Waterloo Municipal Airport (ALO)ORD - ALO
3h 9m$60–286Fly Chicago Midway International Airport to Omaha
- Fly from Chicago Midway International Airport (MDW) to Omaha (OMA)MDW - OMA
3h 17m$128–635Fly Chicago O'Hare International Airport to The Eastern Iowa Airport
- Fly from Chicago O'Hare International Airport (ORD) to The Eastern Iowa Airport (CID)ORD - CID
4h 32m$58–305Bus
- Take the bus from Chicago to Des MoinesChicago
7h 10m$55–160Train, bus
- Take the train from Chicago Union Station to Galesburg Amtrak Station
- Take the bus from Galesburg to Burlington
- Take the bus from Burlington to Des Moines
8h 51m$96–229
Chicago to Iowa by bus
Questions & Answers
The cheapest way to get from Chicago to Iowa is to drive which costs $60 - $90 and takes 5h 29m.
The fastest way to get from Chicago to Iowa is to fly which takes 3h 9m and costs $55 - $290.
Yes, there is a direct bus departing from Chicago and arriving at Des Moines. Services depart twice daily, and operate every day. The journey takes approximately 7h 10m.
The distance between Chicago and Iowa is 324 miles. The road distance is 332 miles.
The best way to get from Chicago to Iowa without a car is to bus via Des Moines which takes 6h 38m and costs $50 - $110.
It takes approximately 3h 23m to get from Chicago to Iowa, including transfers.
Chicago to Iowa bus services, operated by Burlington Trailways, depart from Chicago station.
The best way to get from Chicago to Iowa is to fly which takes 3h 23m and costs $95 - $550. Alternatively, you can bus via Des Moines, which costs $50 - $110 and takes 6h 38m.
Chicago to Iowa bus services, operated by Burlington Trailways, arrive at Des Moines station.
Yes, the driving distance between Chicago to Iowa is 332 miles. It takes approximately 5h 29m to drive from Chicago to Iowa.
What companies run services between Chicago, IL, USA and Iowa, USA?
American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 4 hours. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Des Moines 3 times a day. Tickets cost $45–100 and the journey takes 6h 34m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $80–500
Flights from Chicago O'Hare International Airport to Waterloo Municipal Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $40–260
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $35–250
Flights from Chicago O'Hare International Airport to The Eastern Iowa Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $35–260
- Website
- united.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $80–500
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $35–250
Flights from Chicago O'Hare International Airport to The Eastern Iowa Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $35–260
- Website
- southwest.com
Flights from Chicago Midway International Airport to Omaha
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $100–600
Flights from Chicago Midway International Airport to Omaha via St. Louis
- Ave. Duration
- 3h 50m
- When
- Saturday
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $30–100
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $45–100
- Website
- https://www.greyhound.com/
- Phone
- +1 309-788-3360
- Website
- metroqc.com
Bus from Centre Station to District
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- https://www.metroqc.com
- Adult Cash Fare
- $1
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Chicago to Des Moines
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $55–160
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–95
- Flexible Fares
- $90–130
- Saver Fare
- $55–110
- Flex Fare
- $75–160
Bus from Galesburg to Burlington
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
Bus from Burlington to Des Moines
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
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