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How to get fromChicago to Guelphby train (Amtrak), bus, train, car, plane, bus (Greyhound, Flixbus) or shuttle

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There are 10 ways to get from Chicago to Guelph by train (Amtrak), bus, train, car, plane, bus (Greyhound, Flixbus), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Chicago Union Station to Port Huron Stationtrain train Blue Water
    2. Take the train from Sarnia to Guelphtrain train VIA Rail
    11h 31m
    $84–282

  2. Bus, train

    1. Take the bus from Chicago Bus Station to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Londonbus bus
    3. Take the train from London to Guelphtrain train
    14h 12m
    $103–297

  3. Drive 754.9 km

    1. Drive from Chicago to Guelphcar car 754.9 km
    7h 53m
    $148–214

  4. Fly Chicago O'Hare International Airport to Toronto Pearson International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Toronto Pearson International Airport (YYZ)plane plane ORD - YYZ
    2. Take the train from Bramalea GO to Guelph Central GOtrain train
    6h 57m
    $257–675

  5. Bus

    1. Take the bus from Chicago Bus Station to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Mississaugabus bus
    3. Take the bus from Square One to Guelph Central GO Busbus bus 29
    15h 3m
    $110–274

  6. Fly Chicago Midway International Airport to Toronto Island Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Toronto Island Airport (YTZ)plane plane MDW - YTZ
    2. Take the train from Toronto Union Station to Guelph Central GOtrain train
    7h 9m
    $180–721

  7. Fly Chicago O'Hare International Airport to Erie International Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Erie International Airport (ERI)plane plane ORD - ERI
    2. Drive from Erie-Airport-ERI to Guelphcar car
    6h 59m
    $128–537

  8. Fly Chicago O'Hare International Airport to Toronto Island Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Toronto Island Airport (YTZ)plane plane ORD - YTZ
    2. Take the train from Toronto Union Station to Guelph Central GOtrain train
    7h 25m
    $270–771

  9. Fly Chicago Midway International Airport to Buffalo Niagara International Airport, shuttle, train

    1. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    2. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    3. Take the train from Bramalea GO to Guelph Central GOtrain train
    8h
    $397–1,785

  10. Fly Chicago O'Hare International Airport to Buffalo Niagara International Airport, shuttle, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    2. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    3. Take the train from Bramalea GO to Guelph Central GOtrain train
    8h 31m
    $337–1,385

Chicago to Guelph by train and car

Calendar7Weekly Services
Duration11h 31mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Guelph, ON, Canada?

You can take a train from Chicago Union Station to Guelph via Port Huron Station and Sarnia in around 11h 31m. Alternatively, you can take a bus from Chicago Bus Station to Guelph Central GO Bus via Detroit Bus Station, Mississauga, and Square One in around 15h 3m.

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