There are 6 ways to get from Chicago to Greeneville by plane, car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Mcghee Tyson Airport, drive
best- Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)ORD - TYS
- Drive from Mcghee Tyson Airport (TYS) to Greeneville
5h 2m$108–577Fly to Asheville Regional Airport, drive
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)ORD - AVL
- Drive from S3 + N3 Bus Bay to Greeneville
6h 30m$68–331Bus, drive
- Take the bus from Chicago Bus Station to Toledo Bus Stop
- Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)
- Take the bus from Winston Salem(Trans Center) to Asheville, NC
- Drive from Asheville, NC to Greeneville
23h 34m$116–260Train, bus, drive
- Take the train from Chicago Union Station to Cary
- Take the train from Cary to Greensboro
- Take the bus from Greensboro Bus Stop to Asheville, NC
- Drive from Asheville, NC to Greeneville
32h 26m$161–1,871Drive 552.2 mi
- Drive from Chicago to Greeneville552.2 mi
10h 29m$101–146Fly to Greenville–Spartanburg International Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)ORD - GSP
- Drive from Greenville–Spartanburg International Airport (GSP) to Greeneville
6h 23m$104–490
Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Chicago to Greeneville is to drive which costs $100 - $150 and takes 10h 29m.
The fastest way to get from Chicago to Greeneville is to fly and drive which takes 5h 2m and costs $100 - $600.
The distance between Chicago and Greeneville is 579 miles. The road distance is 555.4 miles.
It takes approximately 5h 2m to get from Chicago to Greeneville, including transfers.
Greeneville is 1h ahead of Chicago. It is currently 11:50 PM in Chicago and 12:50 AM in Greeneville.
Yes, the driving distance between Chicago to Greeneville is 555 miles. It takes approximately 10h 29m to drive from Chicago to Greeneville.
There are 19+ hotels available in Greeneville.
What companies run services between Chicago, IL, USA and Greeneville, TN, USA?
There is no direct connection from Chicago to Greeneville. However, you can take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Mcghee Tyson Airport (TYS), then drive to Greeneville. Alternatively, you can take a bus from Chicago Bus Station to Greeneville via Toledo Bus Stop, Winston Salem(Trans Center), and Asheville, NC in around 23h 34m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $90–550
Flights from Chicago O'Hare International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 5m
- When
- Saturday
- Estimated price
- $110–600
Flights from Chicago O'Hare International Airport to Asheville Regional Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $55–310
Flights from Chicago O'Hare International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $60–340
Flights from Chicago O'Hare International Airport to Asheville Regional Airport via Reagan Washington
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $80–390
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $80–450
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $85–470
- Website
- united.com
Flights from Chicago O'Hare International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $90–550
Flights from Chicago O'Hare International Airport to Asheville Regional Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $55–310
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $80–450
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 24m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- $110–550
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
Flights from Chicago O'Hare International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $65–350
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $95–490
- Website
- southwest.com
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 40m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $85–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Cary
- Ave. Duration
- 24h 21m
- Frequency
- Once daily
- Estimated price
- $100–1,800
- Website
- https://www.amtrak.com/home.html
Train from Cary to Greensboro
- Ave. Duration
- 1h 21m
- Frequency
- 5 times a day
- Estimated price
- $12–15
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Toledo Bus Stop
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- $35–90
- Website
- https://www.greyhound.com/
Bus from Toledo Bus Stop to Winston Salem(Trans Center)
- Ave. Duration
- 12h 40m
- Frequency
- Once daily
- Estimated price
- $60–130
- Website
- https://www.greyhound.com/
Bus from Winston Salem(Trans Center) to Asheville, NC
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $23–29
- Website
- https://www.greyhound.com/
Bus from Greensboro Bus Stop to Asheville, NC
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Chicago Bus Station to Toledo Bus Stop
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $23–65
- Website
- https://baronsbus.com
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