Rome2Rio

How to get fromChicago to Greenevilleby plane, car, bus or train

Find Transport to Greeneville

See all options

There are 6 ways to get from Chicago to Greeneville by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)planeORD - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Greenevillecar
    5h 2m
    $108–577
  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)planeORD - AVL
    2. Drive from S3 + N3 Bus Bay to Greenevillecar
    6h 30m
    $68–331
  3. Bus, drive

    1. Take the bus from Chicago Bus Station to Toledo Bus Stopbus
    2. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus
    4. Drive from Asheville, NC to Greenevillecar
    23h 34m
    $116–260
  4. Train, bus, drive

    1. Take the train from Chicago Union Station to Carytrain
    2. Take the train from Cary to Greensborotrain
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus
    4. Drive from Asheville, NC to Greenevillecar
    32h 26m
    $161–1,871
  5. Drive 552.2 mi

    1. Drive from Chicago to Greenevillecar552.2 mi
    10h 29m
    $101–146
  6. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)planeORD - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Greenevillecar
    6h 23m
    $104–490

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar52Weekly Planes
Duration2h 17mAverage Duration
Ticket$91Cheapest Price
See schedules

Questions & Answers

What companies run services between Chicago, IL, USA and Greeneville, TN, USA?

There is no direct connection from Chicago to Greeneville. However, you can take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Mcghee Tyson Airport (TYS), then drive to Greeneville. Alternatively, you can take a bus from Chicago Bus Station to Greeneville via Toledo Bus Stop, Winston Salem(Trans Center), and Asheville, NC in around 23h 34m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound