There are 5 ways to get from Chicago to Great Smoky Mountains National Park by plane, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville, drive  •  4 h 58 min

  1. Fly from Chicago O'Hare (ORD) to Knoxville (TYS) ORD - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$157 - $434

Cheapest option

Bus, Megabus, drive  •  16 h 49 min

  1. Take the bus from Chicago to Chattanooga
  2. Take the Megabus from Chattanooga to Knoxville
  3. Drive from Knoxville to Great Smoky Mountains National Park

$75 - $101

3 alternative options

Fly to Asheville, drive  •  5 h 17 min

  1. Fly from Chicago O'Hare (ORD) to Asheville (AVL) ORD - AVL
  2. Drive from Asheville to Great Smoky Mountains National Park

$149 - $337

Fly to Greenville/Spartanburg, drive  •  6 h 13 min

  1. Fly from Chicago O'Hare (ORD) to Greenville/Spartanburg (GSP) ORD - GSP
  2. Drive from Greenville/Spartanburg to Great Smoky Mountains National Park

$156 - $576

Drive  •  9 h 39 min

  1. Drive from Chicago to Great Smoky Mountains National Park 607.5 miles

$55 - $90

What companies run services between Chicago, IL, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Chicago to Great Smoky Mountains National Park. However, you can take the subway to O'Hare, take the walk to Chicago O'Hare airport, fly to Knoxville, then take the drive to Great Smoky Mountains National Park. Alternatively, you can take the subway to O'Hare, take the walk to Chicago O'Hare airport, fly to Asheville, then take the drive to Great Smoky Mountains National Park.

Airlines
American Airlines
Website
aa.com
Flights from Chicago O'Hare to Knoxville
Ave. Duration
1 h 41 min
When
Every day
Estimated price
$330 - $750
Flights from Chicago O'Hare to Knoxville via Charlotte
Ave. Duration
3 h 51 min
When
Every day
Estimated price
$330 - $750
Flights from Chicago O'Hare to Asheville via Charlotte
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$290 - $700
Flights from Chicago O'Hare to Greenville/Spartanburg
Ave. Duration
1 h 53 min
When
Every day
Estimated price
$280 - $800
Flights from Chicago O'Hare to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 51 min
When
Every day
Estimated price
$280 - $800
Delta
Website
delta.com
Flights from Chicago O'Hare to Knoxville via Detroit
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$340 - $850
Flights from Chicago O'Hare to Knoxville via Atlanta
Ave. Duration
3 h 51 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$340 - $850
Flights from Chicago O'Hare to Asheville via Atlanta
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$310 - $750
Flights from Chicago O'Hare to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$260 - $1,300
Flights from Chicago O'Hare to Greenville/Spartanburg via Detroit
Ave. Duration
4 h 7 min
When
Saturday
Estimated price
$260 - $1,300
United Airlines
Website
united.com
Flights from Chicago O'Hare to Knoxville
Ave. Duration
1 h 41 min
When
Every day
Estimated price
$300 - $750
Flights from Chicago O'Hare to Asheville
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$290 - $700
Flights from Chicago O'Hare to Greenville/Spartanburg
Ave. Duration
1 h 55 min
When
Every day
Estimated price
$280 - $1,100
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Chicago to Chattanooga
Ave. Duration
12 h 14 min
Frequency
Twice daily
Estimated price
$55 - $70
Schedules at
us.megabus.com
Bus from Chattanooga to Knoxville
Ave. Duration
2 h
Frequency
Twice daily
Estimated price
$12 - $22
Schedules at
us.megabus.com

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including The London Underground: Essential tips to navigate the Tube, Is ride-sharing platform BlaBlaCar right for you? and Best ways to travel around Australia - to help you get the most out of your next trip.

Questions & Answers

The distance between Chicago and Great Smoky Mountains National Park is 784 km. The road distance is 972 km.

The cheapest way to get from Chicago to Great Smoky Mountains National Park is to drive which costs $55 - $90 and takes 9 h 39 min.

The quickest way to get from Chicago to Great Smoky Mountains National Park is to fly and drive which takes 4 h 58 min and costs $150 - $440.

It takes approximately 4 h 58 min to get from Chicago to Great Smoky Mountains National Park, including transfers.

Trips to Great Smoky Mountains National Park

Raleigh to Great Smoky Mountains National Park Buffalo to Great Smoky Mountains National Park Ann Arbor to Great Smoky Mountains National Park Alabama to Great Smoky Mountains National Park Wilmington NC USA to Great Smoky Mountains National Park Tulsa to Great Smoky Mountains National Park New Port Richey to Great Smoky Mountains National Park Miami Airport MIA to Great Smoky Mountains National Park Camden Rd Station Midland Railway to Great Smoky Mountains National Park Houston Hobby Apt Airport HOU to Great Smoky Mountains National Park Calgary to Great Smoky Mountains National Park Disney s Hollywood Studios to Great Smoky Mountains National Park Zion National Park to Great Smoky Mountains National Park White Castle LA USA to Great Smoky Mountains National Park Carrollton GA USA to Great Smoky Mountains National Park Pelham NH USA to Great Smoky Mountains National Park Taco Bell Arena to Great Smoky Mountains National Park Marysville to Great Smoky Mountains National Park Fond du Lac to Great Smoky Mountains National Park Home2 Suites by Hilton Baltimore Downtown to Great Smoky Mountains National Park Youngstown State University to Great Smoky Mountains National Park Leicester to Great Smoky Mountains National Park Hastings NE USA to Great Smoky Mountains National Park Bryan OH USA to Great Smoky Mountains National Park Miami Beach to Great Smoky Mountains National Park Lansing to Great Smoky Mountains National Park Sebring to Great Smoky Mountains National Park West Virginia University to Great Smoky Mountains National Park Frankfort IL USA to Great Smoky Mountains National Park Fremont OH USA to Great Smoky Mountains National Park