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There are 5 ways to get from Chicago to Great Smoky Mountains National Park by plane, bus or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville, travel  •  4 h 14 min

  1. Fly from Chicago O'Hare (ORD) to Knoxville (TYS) ORD - TYS
  2. Travel from Knoxville to Great Smoky Mountains National Park

4 alternative options

Fly to Asheville, travel  •  5 h 19 min

  1. Fly from Chicago O'Hare (ORD) to Asheville (AVL) ORD - AVL
  2. Travel from Asheville to Great Smoky Mountains National Park

Fly to Greenville/Spartanburg, travel  •  6 h 13 min

  1. Fly from Chicago O'Hare (ORD) to Greenville/Spartanburg (GSP) ORD - GSP
  2. Travel from Greenville/Spartanburg to Great Smoky Mountains National Park

Bus, travel  •  26 h 10 min

  1. Take the bus from Chicago, Il to Toledo, Oh
  2. Take the bus from Toledo, Oh to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Travel from Asheville, Nc to Great Smoky Mountains National Park

Train, bus, travel  •  31 h 43 min

  1. Take the train from Chicago Union Station to Charlottesville Amtrak Station
  2. Take the train from Charlottesville Amtrak Station to Greensboro Amtrak Station
  3. Take the bus from Greensboro, Nc to Asheville, Nc
  4. Travel from Asheville, Nc to Great Smoky Mountains National Park

Questions & Answers

The distance between Chicago and Great Smoky Mountains National Park is 490 miles.

The best way to get from Chicago to Great Smoky Mountains National Park without a car is to bus and travel which takes 26 h 10 min and costs .

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It takes approximately 4 h 14 min to get from Chicago to Great Smoky Mountains National Park, including transfers.

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The quickest flight from Chicago O'Hare Airport to Knoxville Airport is the direct flight which takes 1 h 33 min.

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Great Smoky Mountains National Park is 1 h ahead of Chicago. It is currently 6:47 PM in Chicago and 7:47 PM in Great Smoky Mountains National Park.

Delta, American Airlines and United Airlines offer flights from Chicago O'Hare Airport to Knoxville Airport.

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There are 1687+ hotels available in Great Smoky Mountains National Park. Prices start at $62 USD per night.

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The best way to get from Chicago to Chicago O'Hare Airport is to subway which takes 42 min and costs $2 - $5.

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Map of how to get from Chicago to Great Smoky Mountains National Park.
Launch map view
  • Distance: 489.8 miles
  • Duration: 4 h 14 min

What companies run services between Chicago, IL, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Chicago to Great Smoky Mountains National Park. However, you can take the subway to O'Hare, take the walk to Chicago O'Hare airport, fly to Knoxville, then take the travel to Great Smoky Mountains National Park. Alternatively, you can take the subway to O'Hare, take the walk to Chicago O'Hare airport, fly to Asheville, then take the travel to Great Smoky Mountains National Park.

Airlines
American Airlines
Website
aa.com
Flights from Chicago O'Hare to Knoxville
Ave. Duration
1 h 36 min
When
Every day
Estimated price
$330 - $750
Flights from Chicago O'Hare to Knoxville via Charlotte
Ave. Duration
3 h 43 min
When
Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$330 - $750
Flights from Chicago O'Hare to Asheville via Charlotte
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$290 - $700
Flights from Chicago O'Hare to Greenville/Spartanburg
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$280 - $800
Flights from Chicago O'Hare to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$280 - $800
United Airlines
Website
united.com
Flights from Chicago O'Hare to Knoxville
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$300 - $750
Flights from Chicago O'Hare to Asheville
Ave. Duration
1 h 50 min
When
Every day
Estimated price
$290 - $700
Flights from Chicago O'Hare to Greenville/Spartanburg
Ave. Duration
1 h 55 min
When
Every day
Estimated price
$280 - $1,100
Delta
Website
delta.com
Flights from Chicago O'Hare to Knoxville via Atlanta
Ave. Duration
3 h 53 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$340 - $850
Flights from Chicago O'Hare to Asheville via Atlanta
Ave. Duration
4 h 8 min
When
Every day
Estimated price
$310 - $750
Flights from Chicago O'Hare to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 53 min
When
Saturday
Estimated price
$260 - $1,300
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Chicago Union Station to Charlottesville Amtrak Station
Ave. Duration
20 h 25 min
Frequency
4 times a week
Estimated price
$110 - $320
Website
amtrak.com
Coach Seat
$110 - $170
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $320
Room
$450 - $650
Train from Charlottesville Amtrak Station to Greensboro Amtrak Station
Ave. Duration
3 h 23 min
Frequency
Once daily
Estimated price
$35 - $90
Website
amtrak.com
Coach Seat
$35 - $60
Flexi Coach Seat
$65 - $100
Business Coach Seat
$65 - $90
Room
$190 - $260
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Chicago, Il to Toledo, Oh
Ave. Duration
4 h 50 min
Frequency
3 times a day
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Bus from Toledo, Oh to Winston Salem, Nc
Ave. Duration
14 h 40 min
Frequency
3 times a day
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Once daily
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Greensboro, Nc to Asheville, Nc
Ave. Duration
4 h 10 min
Frequency
Once daily
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55

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Trips to Great Smoky Mountains National Park