There are 5 ways to get from Chicago to Durham by subway, plane, bus, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Chicago Midway International Airport, fly, bus, line 700 bus
best- Take the subway from Roosevelt to Midway
- Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)MDW - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Center
- Take the bus from Regional Transit Center to Durham Station Gate J
4h 53m$82–458Bus
- Take the bus from Chicago Bus Station to Toledo Bus Stop
- Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)
- Take the bus from Winston Salem(Trans Center) to Durham
21h 30m$100–276Train (Amtrak)
- Take the train from Chicago Union Station to CaryFloridian
25h 39m$116–1,796Drive 765.7 mi
- Drive from Chicago to Durham765.7 mi
13h 21m$140–202Fly from Chicago O'Hare International Airport, bus, line 700 bus
- Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)ORD - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Center
- Take the bus from Regional Transit Center to Durham Station Gate J
5h 22m$92–398
Chicago to Durham by bus
Questions & Answers
The cheapest way to get from Chicago to Durham is to bus which costs $100 - $280 and takes 21h 30m.
The fastest way to get from Chicago to Durham is to subway and fly and bus and line 700 bus which takes 4h 53m and costs $80 - $460.
No, there is no direct bus from Chicago station to Durham. However, there are services departing from Chicago Bus Station and arriving at Durham via Toledo Bus Stop and Winston Salem(Trans Center). The journey, including transfers, takes approximately 21h 30m.
No, there is no direct train from Chicago station to Durham station. However, there are services departing from Chicago Union Station and arriving at Durham Amtrak Station via Cary. The journey, including transfers, takes approximately 25h 39m.
The distance between Chicago and Durham is 660 miles. The road distance is 770.2 miles.
The best way to get from Chicago to Durham without a car is to bus which takes 21h 30m and costs $100 - $280.
It takes approximately 4h 53m to get from Chicago to Durham, including transfers.
Chicago to Durham bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Durham train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Durham is to bus which takes 21h 30m and costs $100 - $280. Alternatively, you can train, which costs $110 - $1,800 and takes 25h 39m.
What companies run services between Chicago, IL, USA and Durham, NC, USA?
You can take a bus from Chicago Bus Station to Durham via Toledo Bus Stop and Winston Salem(Trans Center) in around 21h 30m. Alternatively, Amtrak operates a train from Chicago Union Station to Cary once daily. Tickets cost $100–1,800 and the journey takes 24h 21m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $65–370
- Website
- southwest.com
Flights from Chicago Midway International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $80–450
- Website
- united.com
Flights from Chicago O'Hare International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $65–370
- Website
- flyfrontier.com
Flights from Chicago O'Hare International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 5m
- When
- Tuesday and Sunday
- Estimated price
- $65–370
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Roosevelt to Midway
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Cary
- Ave. Duration
- 24h 21m
- Frequency
- Once daily
- Estimated price
- $100–1,800
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 919 485 7433
- customerservice@gotriangle.org
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 15 min
- Frequency
- Hourly
- Estimated price
- $1–3
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
- Seniors 65+, youth 12 and under
- $0
- disabled, medicare
- $1
- Regular one-way fare
- $3
Bus from Regional Transit Center to Durham Station Gate J
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Website
- https://gotriangle.org/
- Schedules at
- https://gotriangle.org/maps-schedules/gotriangle
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Toledo Bus Stop
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- $35–90
- Website
- https://www.greyhound.com/
Bus from Toledo Bus Stop to Winston Salem(Trans Center)
- Ave. Duration
- 12h 40m
- Frequency
- Once daily
- Estimated price
- $60–130
- Website
- https://www.greyhound.com/
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $17–60
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Chicago Bus Station to Toledo Bus Stop
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $23–65
- Website
- https://baronsbus.com
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More Questions & Answers
Chicago to Durham bus services, operated by Greyhound USA, arrive at Toledo Bus Stop station.
Durham is 1h ahead of Chicago. It is currently 2:07 PM in Chicago and 3:07 PM in Durham.
Chicago to Durham train services, operated by Amtrak, arrive at Cary station.
Yes, the driving distance between Chicago to Durham is 770 miles. It takes approximately 13h 21m to drive from Chicago to Durham.
Book your Chicago to Durham train tickets online with Omio.
Book your Chicago to Durham bus tickets online with Omio and FlixBus.
There are 328+ hotels available in Durham.