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How to get fromChicago to Duke Universityby plane, bus, bus (Greyhound), train, car or subway

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There are 6 ways to get from Chicago to Duke University by plane, bus, bus (Greyhound), train, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane plane ORD - RDU
    2. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    3. Take the bus from Regional Transit Center to Durham Station Gate Jbus bus
    4. Take the bus from Durham Station to Flowers Dr at Duke Gardensbus bus
    6h 4m
    $94–369
  2. Subway to Chicago Midway International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus, line 6 bus

    cheapest
    1. Take the subway from Roosevelt to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    4. Take the bus from Regional Transit Center to Durham Station Gate Jbus bus
    5. Take the bus from Durham Station to Flowers Dr at Duke Gardensbus bus
    5h 35m
    $88–509
  3. Bus

    1. Take the bus from Chicago Bus Station to Toledo Bus Stopbus bus
    2. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    22h 6m
    $111–275
  4. Train, bus

    1. Take the train from Chicago Union Station to Raleigh Union Stationtrain train Floridian
    2. Take the bus from Union Station - Bus Platform A to Chapel Dr at Duke University Rdbus bus Drx
    26h 5m
    $142–386
  5. Drive 764 mi

    1. Drive from Chicago to Duke Universitycar car 764 mi
    13h 25m
    $140–202
  6. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    8h 12m
    $108–505

Chicago to Duke University by bus and foot

Calendar7Weekly Services
Duration22h 6mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Duke University, NC, USA?

You can take a bus from Chicago Bus Station to Duke University via Toledo Bus Stop, Winston Salem(Trans Center), Durham, Durham Station, and Flowers Dr at Duke Gardens in around 22h 6m.

Airlines
Train operators
Bus operators

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