Travel within United States is: Fully open. See details.

There are 8 ways to get from Chicago to Du Quoin by train, car, plane, bus or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  4h 34m

  1. Take the train from Chicago Union Station to Du Quoin Amtrak Station Illini / ...

$40 - $65

7 alternative options

Drive  •  5h 25m

  1. Drive from Chicago to Du Quoin 319.3 miles

$30 - $45

Fly Chicago O'Hare to Cape Girardeau, drive  •  4h 55m

  1. Fly from Chicago O'Hare (ORD) to Cape Girardeau (CGI) ORD - CGI
  2. Drive from Cape Girardeau to Du Quoin

$100 - $406

Fly Chicago Midway to St. Louis, Amtrak Thruway  •  7h 42m

  1. Fly from Chicago Midway (MDW) to St. Louis (STL) MDW - STL
  2. Take the Amtrak Thruway from St. Louis, MO - Amtrak to Carbondale,IL - Amtrak

Fly Chicago O'Hare to St. Louis, Amtrak Thruway  •  7h 58m

  1. Fly from Chicago O'Hare (ORD) to St. Louis (STL) ORD - STL
  2. Take the Amtrak Thruway from St. Louis, MO - Amtrak to Carbondale,IL - Amtrak

Fly Chicago Midway to Marion  •  5h 18m

  1. Fly from Chicago Midway (MDW) to Marion (MWA) MDW - MWA

$112 - $225

Fly Chicago O'Hare to Paducah, bus  •  7h 37m

  1. Fly from Chicago O'Hare (ORD) to Paducah (PAH) ORD - PAH
  2. Take the bus from Paducah to Carbondale

$180 - $592

Fly Chicago O'Hare to Evansville, bus, taxi  •  7h 50m

  1. Fly from Chicago O'Hare (ORD) to Evansville (EVV) ORD - EVV
  2. Take the bus from Evansville to Mt Vernon
  3. Take a taxi from Mt Vernon to Du Quoin

$232 - $520

Chicago to Du Quoin by trains

The train journey time between Chicago and Du Quoin is around 4h 34m and covers a distance of around 291 miles. The fastest train normally takes 4h 34m. Operated by Amtrak, the Chicago to Du Quoin train service departs from Chicago Union Station and arrives in Du Quoin Amtrak Station. Typically seven trains run weekly, although weekend and holiday schedules can vary so check in advance.

Train route overview

Average train time:
4h 34m
Fastest train time:
4h 34m
Trains per week:
7
Cheapest price:
$40
Carbon emissions:
24 kg CO2

First and last trains

First train departs at:
16:05
Last train departs at:
16:05

The schedules shown below are for the next available departures.

Chicago to Du Quoin train schedules

Chicago → Du Quoin
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Travel safe during COVID-19

Rules to follow in United States

2m

Recommended

Travel within United States

Domestic border crossings may be subject to approval, testing and quarantine
Nationwide control measures in place

COVID-19 help in United States

If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 800-232-4636

Frequently Asked Questions


Yes, travel within United States is currently allowed.

Explore travel options

Domestic travel is not restricted, but some conditions may apply

  • Face masks are recommended
  • There is a social distancing requirement of 2 metres
  • Domestic border crossings may be subject to approval, testing and quarantine
  • Nationwide control measures in place

Explore travel options

The national COVID-19 helpline number in Du Quoin is 800-232-4636.

Wearing a face mask on public transport in Du Quoin is recommended.

The social distance requirement in Du Quoin is 2 metres.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.

Last updated: 8 Jun 2021
Exceptions may apply, for full details: Centers for Disease control and prevention (CDC).

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Chicago to Du Quoin is to drive which costs $30 - $45 and takes 5h 25m.

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The fastest way to get from Chicago to Du Quoin is to train. Taking this option will cost $40 - $65 and takes 4h 34m.

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Yes, there is a direct train departing from Chicago Union Station station and arriving at Du Quoin Amtrak Station station. Services depart twice daily, and operate every day. The journey takes approximately 4h 34m.

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The distance between Chicago and Du Quoin is 282 miles. The road distance is 319.3 miles.

Get driving directions

The best way to get from Chicago to Du Quoin without a car is to train which takes 4h 34m and costs $40 - $65.

More details

The train from Chicago Union Station to Du Quoin Amtrak Station takes 4h 34m including transfers and departs twice daily.

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Chicago to Du Quoin train services, operated by Amtrak, depart from Chicago Union Station.

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The best way to get from Chicago to Du Quoin is to train which takes 4h 34m and costs $40 - $65. Alternatively, you can fly, which costs $110 - $230 and takes 5h 18m.

Mode details

The quickest flight from Chicago O'Hare Airport to Cape Girardeau Airport is the direct flight which takes 1h 27m.

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Chicago to Du Quoin train services, operated by Amtrak, arrive at Du Quoin Amtrak Station.

More details

Map of how to get from Chicago to Du Quoin.
Launch map view
  • Distance: 281.9 miles
  • Duration: 4h 34m

What companies run services between Chicago, IL, USA and Du Quoin, IL, USA?

Amtrak operates a train from Chicago Union Station to Du Quoin Amtrak Station twice daily. Tickets cost $40 - $65 and the journey takes 4h 34m. Alternatively, Southwest Airlines, Cape Air and Delta fly from Chicago to Du Quoin every 4 hours.

Airlines
American Airlines
Website
aa.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1h 18m
When
Every day
Estimated price
$100 - $330
Flights from Chicago O'Hare to St. Louis via Quincy
Ave. Duration
2h 58m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $270
Flights from Chicago Midway to Marion via St. Louis
Ave. Duration
3h 31m
When
Every day
Estimated price
$35 - $130
Flights from Chicago Midway to Marion via Nashville
Ave. Duration
4h 18m
When
Monday to Saturday
Estimated price
$40 - $140
Flights from Chicago Midway to Marion via Detroit, St. Louis
Ave. Duration
6h 3m
When
Saturday and Sunday
Estimated price
$35 - $160
Flights from Chicago Midway to Marion via Atlanta, St. Louis
Ave. Duration
6h 30m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$45 - $160
Flights from Chicago Midway to Marion via Atlanta, Nashville
Ave. Duration
6h 45m
When
Sunday
Estimated price
$45 - $160
Flights from Chicago Midway to Marion via Nashville, St. Louis
Ave. Duration
7h 4m
When
Sunday
Estimated price
$40 - $150
Flights from Chicago O'Hare to Evansville
Ave. Duration
1h 17m
When
Every day
Estimated price
$100 - $410
United Airlines
Website
united.com
Flights from Chicago O'Hare to Cape Girardeau
Ave. Duration
1h 32m
When
Every day
Estimated price
$90 - $390
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1h 23m
When
Every day
Estimated price
$100 - $360
Flights from Chicago O'Hare to Paducah
Ave. Duration
1h 30m
When
Every day
Estimated price
$110 - $490
Flights from Chicago O'Hare to Evansville
Ave. Duration
1h 18m
When
Every day
Estimated price
$220 - $450
Cape Air
Website
capeair.com
Flights from Chicago O'Hare to St. Louis via Quincy
Ave. Duration
2h 58m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$120 - $270
Flights from Chicago Midway to Marion via St. Louis
Ave. Duration
3h 31m
When
Every day
Estimated price
$35 - $130
Flights from Chicago Midway to Marion via Nashville
Ave. Duration
4h 18m
When
Monday to Saturday
Estimated price
$40 - $140
Flights from Chicago Midway to Marion via Detroit, St. Louis
Ave. Duration
6h 3m
When
Saturday and Sunday
Estimated price
$35 - $160
Flights from Chicago Midway to Marion via Atlanta, St. Louis
Ave. Duration
6h 30m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$45 - $160
Flights from Chicago Midway to Marion via Atlanta, Nashville
Ave. Duration
6h 45m
When
Sunday
Estimated price
$45 - $160
Flights from Chicago Midway to Marion via Nashville, St. Louis
Ave. Duration
7h 4m
When
Sunday
Estimated price
$40 - $150
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to St. Louis
Ave. Duration
1h 10m
When
Every day
Estimated price
$90 - $300
GoJet Airlines
Website
gojetairlines.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1h 22m
When
Every day
Estimated price
$22 - $290
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Chicago Union Station to Du Quoin Amtrak Station
Ave. Duration
4h 34m
Frequency
Twice daily
Estimated price
$40 - $65
Schedules at
amtrak.com
Coach Seat
$40 - $65
Premium
$220 - $300
Flexi Coach Seat
$75 - $120
Business Seat
$75 - $110
Bus operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Bus from St. Louis, MO - Amtrak to Carbondale,IL - Amtrak
Ave. Duration
2h
Frequency
6 times a week
Schedules at
amtrak.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Paducah to Carbondale
Ave. Duration
1h 50m
Frequency
Once daily
Estimated price
$15 - $22
Website
greyhound.com
Economy
$15 - $22
Flexible
$30 - $50
Bus from Evansville to Mt Vernon
Ave. Duration
1h 45m
Frequency
Once daily
Estimated price
$16 - $23
Website
greyhound.com
Economy
$16 - $23
Flexible
$30 - $50
Other operators
Taxi from Mt Vernon to Du Quoin
Ave. Duration
54 min
Estimated price
$95 - $120

Want to know more about travelling around United States

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More Questions & Answers

Yes, the driving distance between Chicago to Du Quoin is 319 miles. It takes approximately 5h 25m to drive from Chicago to Du Quoin.

Get driving directions

United Airlines offers flights from Chicago O'Hare Airport to Cape Girardeau Airport.

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Book your Chicago to Du Quoin train tickets online with Omio.

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There are four+ hotels available in Du Quoin. Prices start at $100 USD per night.

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The best way to get from Chicago to Chicago O'Hare Airport is to subway which takes 42 min and costs $2 - $5.

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