There are 6 ways to get from Chicago to Du Quoin by train, car, plane, bus or night bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  4 h 34 min

  1. Take the train from Chicago Union Station Amtrak to Du Quoin Amtrak Illini / ...

$50 - $140

5 alternative options

Drive  •  5 h 23 min

  1. Drive from Chicago to Du Quoin 319.3 miles

$30 - $45

Fly Chicago O'Hare to Cape Girardeau, drive  •  5 h 2 min

  1. Fly from Chicago O'Hare (ORD) to Cape Girardeau (CGI) ORD - CGI
  2. Drive from Cape Girardeau to Du Quoin

$139 - $666

Fly Chicago O'Hare to Paducah, bus  •  6 h 44 min

  1. Fly from Chicago O'Hare (ORD) to Paducah (PAH) ORD - PAH
  2. Take the bus from Paducah, Ky to Carbondale

$163 - $453

Fly Chicago Midway to St. Louis, night bus  •  7 h 19 min

  1. Fly from Chicago Midway (MDW) to St. Louis (STL) MDW - STL
  2. Take the night bus from St Louis, Mo to Carbondale

$166 - $401

Fly Chicago O'Hare to St. Louis, night bus  •  7 h 35 min

  1. Fly from Chicago O'Hare (ORD) to St. Louis (STL) ORD - STL
  2. Take the night bus from St Louis, Mo to Carbondale

$131 - $342

What companies run services between Chicago, IL, USA and Du Quoin, IL, USA?

Amtrak operates a train from Chicago to Du Quoin twice daily. Tickets cost $50 - $140 and the journey takes 4 h 34 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to St. Louis
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$160 - $550
United Airlines
Website
united.com
Flights from Chicago O'Hare to Cape Girardeau
Ave. Duration
1 h 32 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $650
Flights from Chicago O'Hare to Cape Girardeau via Quincy
Ave. Duration
2 h 48 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $700
Flights from Chicago O'Hare to Paducah
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$170 - $400
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$120 - $650
American Airlines
Website
aa.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$120 - $550
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Chicago Union Station Amtrak to Du Quoin Amtrak
Ave. Duration
4 h 34 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $130
Business Coach Seat
$95 - $140
Room
$230 - $330
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Paducah, Ky to Carbondale
Ave. Duration
1 h 40 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$24 - $35
Night bus from St Louis, Mo to Carbondale
Ave. Duration
1 h 55 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$29 - $40

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Questions & Answers

How far is it from Chicago to Du Quoin?

The distance between Chicago and Du Quoin is 451 km. The road distance is 511 km.

What is the cheapest way to get from Chicago to Du Quoin?

The cheapest way to get from Chicago to Du Quoin is to drive which costs $30 - $45 and takes 5 h 23 min.

What is the fastest way to get from Chicago to Du Quoin?

The quickest way to get from Chicago to Du Quoin is to train which takes 4 h 34 min and costs $50 - $140.

Is there a direct train between Chicago and Du Quoin?

Yes, there is a direct train departing from Chicago Union Station Amtrak and arriving at Du Quoin Amtrak. Services depart twice daily, and operate every day. The journey takes approximately 4 h 34 min.

How long does it take to get from Chicago to Du Quoin?

The train from Chicago Union Station Amtrak to Du Quoin Amtrak takes 4 h 34 min including transfers and departs twice daily.