There are 6 ways to get from Chicago to Du Quoin by train, car, plane, bus or night bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  4 h 34 min

  1. Take the train from Chicago Union Station Amtrak to Du Quoin Amtrak Illini / ...

$50 - $140

5 alternative options

Drive  •  5 h 23 min

  1. Drive from Chicago to Du Quoin 319.3 miles

$30 - $45

Fly Chicago O'Hare to Cape Girardeau, drive  •  5 h 3 min

  1. Fly from Chicago O'Hare (ORD) to Cape Girardeau (CGI) ORD - CGI
  2. Drive from Cape Girardeau to Du Quoin

$139 - $666

Fly Chicago O'Hare to Paducah, bus  •  6 h 51 min

  1. Fly from Chicago O'Hare (ORD) to Paducah (PAH) ORD - PAH
  2. Take the bus from Paducah, Ky to Carbondale

$163 - $453

Fly Chicago Midway to St. Louis, night bus  •  7 h 15 min

  1. Fly from Chicago Midway (MDW) to St. Louis (STL) MDW - STL
  2. Take the night bus from St Louis, Mo to Carbondale

$166 - $401

Fly Chicago O'Hare to St. Louis, night bus  •  7 h 28 min

  1. Fly from Chicago O'Hare (ORD) to St. Louis (STL) ORD - STL
  2. Take the night bus from St Louis, Mo to Carbondale

$131 - $342

Questions & Answers

The cheapest way to get from Chicago to Du Quoin is to drive which costs $30 - $45 and takes 5 h 23 min.

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The quickest way to get from Chicago to Du Quoin is to train which costs $50 - $140 and takes 4 h 34 min.

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The distance between Chicago and Du Quoin is 282 miles. The road distance is 319.3 miles.

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The train from Chicago Union Station Amtrak to Du Quoin Amtrak takes 4 h 34 min including transfers and departs twice daily.

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Yes, there is a direct train departing from Chicago Union Station Amtrak station and arriving at Du Quoin Amtrak. Services depart twice daily, and operate every day. The journey takes approximately 4 h 34 min.

More details

United Airlines offers flights from Chicago O'Hare Airport to Cape Girardeau Airport.

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Map of how to get from Chicago to Du Quoin.
Launch map view
  • Distance: 281.9 miles
  • Duration: 4 h 34 min

What companies run services between Chicago, IL, USA and Du Quoin, IL, USA?

Amtrak operates a train from Chicago to Du Quoin twice daily. Tickets cost $50 - $140 and the journey takes 4 h 34 min.

Airlines
United Airlines
Website
united.com
Flights from Chicago O'Hare to Cape Girardeau
Ave. Duration
1 h 33 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $650
Flights from Chicago O'Hare to Cape Girardeau via Quincy
Ave. Duration
3 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $700
Flights from Chicago O'Hare to Paducah
Ave. Duration
1 h 24 min
When
Every day
Estimated price
$170 - $400
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$120 - $650
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to St. Louis
Ave. Duration
1 h 4 min
When
Every day
Estimated price
$160 - $550
American Airlines
Website
aa.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$120 - $550
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Chicago Union Station Amtrak to Du Quoin Amtrak
Ave. Duration
4 h 34 min
Frequency
Twice daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $130
Business Coach Seat
$95 - $140
Room
$230 - $330
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Paducah, Ky to Carbondale
Ave. Duration
1 h 40 min
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$24 - $35
Night bus from St Louis, Mo to Carbondale
Ave. Duration
1 h 55 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$29 - $40

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