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How to get fromChicago to Depueby train (Amtrak), bus (Greyhound), car or plane

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There are 4 ways to get from Chicago to Depue by train (Amtrak), bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to Princeton Stationtrain train Southwest Chief / ...
    2h 6m
    $48–96
  2. Drive 108.2 mi

    cheapest
    1. Drive from Chicago to Depuecar car 108.2 mi
    1h 59m
    $20–29
  3. Bus (Greyhound)

    1. Take the bus from Chicago Bus Station to Oglesbybus bus Greyhound US0145S
    4h 3m
    $67–94
  4. Fly, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane plane ORD - MLI
    2. Drive from Moline-Airport-MLI to Depuecar car
    4h 8m
    $44–274

Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI) flights

Calendar41Weekly Planes
Duration1h 12mAverage Duration
Ticket$32Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Depue, IL, USA?

Amtrak operates a train from Chicago Union Station to Princeton Station 4 times a day. Tickets cost $13–50 and the journey takes 1h 44m. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Oglesby once daily. Tickets cost $26–40 and the journey takes 3h 40m.

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