Rome2Rio

How to get fromChicago to Clinton, MOby plane, car, train, bus, or bus (Greyhound)

Find Transport to Clinton, MO

See all options

There are 7 ways to get from Chicago to Clinton, MO by plane, car, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Columbia Regional Airport, drive

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane plane ORD - COU
    2. Drive from Columbia Regional Airport (COU) to Clinton, MOcar car
    5h 49m
    $70–340

  2. Train, bus

    1. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    2. Take the bus from Kansas City to Clinton, MObus bus Jefferson 121
    10h 19m
    $172–320

  3. Bus

    1. Take the bus from Chicago Bus Station to Des Moinesbus bus
    2. Take the bus from Des Moines to Kansas Citybus bus
    3. Take the bus from Kansas City to Clinton, MObus bus
    13h 10m
    $128–207

  4. Drive 492.6 mi

    1. Drive from Chicago to Clinton, MOcar car 492.6 mi
    8h 54m
    $90–130

  5. Fly Chicago O'Hare International Airport to Springfield-Branson National Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)plane plane ORD - SGF
    2. Take the bus from Springfield to Clinton, MObus bus
    6h 25m
    $96–391

  6. Fly Chicago Midway International Airport to Kansas City, bus

    1. Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)plane plane MDW - MCI
    2. Take the bus from Kansas City to Clinton, MObus bus
    6h 56m
    $150–795

  7. Fly Chicago O'Hare International Airport to Kansas City, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Kansas City (MCI)plane plane ORD - MCI
    2. Take the bus from Kansas City to Clinton, MObus bus
    7h 22m
    $380–795

Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU) flights

Calendar42Weekly Planes
Duration1h 32mAverage Duration
Ticket$48Cheapest Price
See schedules

Questions & Answers

Map of how to get from Chicago to Clinton, MO.ExpandLaunch map view
  • Distance: 454.4 mi
  • Duration: 5h 49m

What companies run services between Chicago, IL, USA and Clinton, MO, USA?

You can take a bus from Chicago Bus Station to Clinton, MO via Des Moines and Kansas City in around 13h 10m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound