There are 7 ways to get from Chicago to Clemson by plane, taxi, bus, train (Amtrak), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Greenville–Spartanburg International Airport, taxi
best- Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)ORD - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Clemson
4h 35m$182–585Fly to Asheville Regional Airport, drive
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)ORD - AVL
- Drive from Asheville-Airport-AVL to Clemson
5h 12m$70–334Bus, taxi
- Take the bus from Chicago Bus Station to Atlanta Bus Station
- Take the bus from Atlanta to Taqueria Guadalajara - Greenville
- Take the taxi from Taqueria Guadalajara - Greenville to Clemson
20h 26m$200–461Train (Amtrak)
- Take the train from Chicago Union Station to CharlottesvilleCardinal
- Take the train from Charlottesville to Clemson Amtrak StationCrescent
30h 55m$217–849Drive 679 mi
- Drive from Chicago to Clemson679 mi
13h 9m$124–179Bus
- Take the bus from Chicago Train Station to Atlanta Bus StationGreyhound US0100
- Take the bus from Atlanta to Taqueria Guadalajara - GreenvilleCharlotte
22h 28m$205–458Train via Cary (Amtrak)
- Take the train from Chicago Union Station to Cary
- Take the train from Cary to Charlotte Amtrak Station
- Take the train from Charlotte Amtrak Station to Clemson Amtrak Station
32h 31m$182–1,941
Chicago to Clemson by train (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Clemson is to drive which costs $120 - $180 and takes 13h 9m.
The fastest way to get from Chicago to Clemson is to fly and taxi which takes 4h 35m and costs $180 - $600.
No, there is no direct train from Chicago station to Clemson station. However, there are services departing from Chicago Union Station and arriving at Clemson Amtrak Station via Charlottesville. The journey, including transfers, takes approximately 30h 55m.
The distance between Chicago and Clemson is 642 miles. The road distance is 683 miles.
The best way to get from Chicago to Clemson without a car is to bus and taxi which takes 20h 26m and costs $200 - $470.
It takes approximately 4h 35m to get from Chicago to Clemson, including transfers.
Chicago to Clemson train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Clemson is to train which takes 30h 55m and costs $210 - $850. Alternatively, you can bus, which costs $200 - $460 and takes 22h 28m.
Clemson is 1h ahead of Chicago. It is currently 11:51 PM in Chicago and 12:51 AM in Clemson.
Chicago to Clemson train services, operated by Amtrak, arrive at Charlottesville station.
What companies run services between Chicago, IL, USA and Clemson, SC, USA?
You can take a train from Chicago Union Station to Clemson Amtrak Station via Charlottesville in around 30h 55m. Alternatively, you can take a bus from Chicago Train Station to Downtown Clemson/Tiger Town Tavern via Atlanta Bus Station, Garnett Station, Chamblee Station, Atlanta, Taqueria Guadalajara - Greenville, and Southern Wesleyan University in around 22h 28m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $80–450
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $85–470
Flights from Chicago O'Hare International Airport to Asheville Regional Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $55–310
Flights from Chicago O'Hare International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $60–340
- Website
- united.com
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $80–450
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 24m
- When
- Monday to Friday
- Estimated price
- $110–550
Flights from Chicago O'Hare International Airport to Asheville Regional Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $55–310
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $95–490
Flights from Chicago O'Hare International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $65–350
- Website
- southwest.com
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 40m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $85–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Charlottesville
- Ave. Duration
- 20h 40m
- Frequency
- 3 times a week
- Estimated price
- $170–700
- Website
- https://www.amtrak.com/home.html
Train from Charlottesville to Clemson Amtrak Station
- Ave. Duration
- 9h 15m
- Frequency
- Once daily
- Estimated price
- $40–150
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $40–100
- Coach Seat short notice purchase
- $50–150
- Business - advance purchase
- $70–310
- Business Class
- $110–340
Train from Chicago Union Station to Cary
- Ave. Duration
- 24h 21m
- Frequency
- Once daily
- Estimated price
- $100–1,800
- Website
- https://www.amtrak.com/home.html
Train from Cary to Charlotte Amtrak Station
- Ave. Duration
- 2h 58m
- Frequency
- 5 times a day
- Estimated price
- $28–33
- Website
- https://www.amtrak.com/home.html
Train from Charlotte Amtrak Station to Clemson Amtrak Station
- Ave. Duration
- 3h 12m
- Frequency
- Once daily
- Estimated price
- $45–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- 3 times a day
- Estimated price
- $85–200
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 15m
- Frequency
- 4 times a day
- Estimated price
- $75–220
- Website
- https://www.greyhound.com/
Bus from Chicago Train Station to Atlanta Bus Station
- Ave. Duration
- 15h 55m
- Frequency
- Twice daily
- Estimated price
- $75–210
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–150
- Ave. Duration
- 45 min
- Estimated price
- $70–130
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Corporate Taxi
- Phone
- +1 864-990-5556
- Website
- ataxi.co
Atlantis Taxi
- Phone
- +1 850-628-5670
- Website
- facebook.com
Checker Cab
- Phone
- +1 864-583-2721
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Corporate Taxi
- Phone
- +1 864-990-5556
- Website
- ataxi.co
Atlantis Taxi
- Phone
- +1 850-628-5670
- Website
- facebook.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Chicago to Clemson is 683 miles. It takes approximately 13h 9m to drive from Chicago to Clemson.
Book your Chicago to Clemson train tickets online with Omio.
There are 101+ hotels available in Clemson.









