There are 11 ways to get from Chicago to Cholula by plane, bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Hermanos Serdán International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Hermanos Serdán International Airport (PBC)plane ORD - PBC
9h 15m$2,353–9,336Bus
- Take the bus from Chicago to San Luis Potosíbus Chicago
- Take the bus from San Luis Potosí to Pueblabus
45h 38m$5,221–9,239Train, bus via Nuevo Laredo
- Take the train from Chicago Union Station to San Antonio Stationtrain
- Take the bus from San Antonio Station to Nuevo Laredobus
- Take the bus from Nuevo Laredo to Terminal Central Del Sur - Taxqueñabus
- Take the bus from Terminal Central Del Sur - Taxqueña to Puebla Terminal CAPUbus
2d 2h$10,434–19,879Drive 3,211.9 km
- Drive from Chicago to Cholulacar 3,211.9 km
35h 38m$6,271–9,058Fly Chicago Midway International Airport to Hermanos Serdán International Airport
- Fly from Chicago Midway International Airport (MDW) to Hermanos Serdán International Airport (PBC)plane MDW - PBC
10h 19m$3,953–15,336Fly Chicago O'Hare International Airport to Benito Juárez International Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Benito Juárez International Airport (MEX)plane ORD - MEX
- Take the bus from Terminal de Autobuses de Pasajeros de Oriente to Cholula 12 Ponientebus
9h 59m$2,819–6,356Fly Chicago Midway International Airport to Benito Juárez International Airport, bus
- Fly from Chicago Midway International Airport (MDW) to Benito Juárez International Airport (MEX)plane MDW - MEX
- Take the bus from Terminal de Autobuses de Pasajeros de Oriente to Cholula 12 Ponientebus
11h 33m$3,119–13,356Fly Chicago O'Hare International Airport to Felipe Ángeles International Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Felipe Ángeles International Airport (NLU)plane ORD - NLU
- Take the bus from Terminal de Autobuses de Pasajeros de Oriente to Cholula 12 Ponientebus
13h 32m$2,359–9,066Bus via Omaha
- Take the bus from Chicago Bus Station to Omaha, NEbus
- Take the bus from Omaha to Saltillobus
- Take the bus from Saltillo to Pueblabus
2d 7h$6,423–8,746Bus via Morelia
- Take the bus from Chicago to Moreliabus
- Take the bus from Morelia to Puebla CAPUbus
2d 7h$6,031–6,534Train, bus
- Take the train from Chicago Union Station to San Marcos Amtraktrain
- Take the bus from San Marcos to Terminal Central de Autobuses del Nortebus
- Take the bus from Mexico City Degollado to Pueblabus
2d 8h$8,902–17,608
Chicago O'Hare International Airport (ORD) to Hermanos Serdán International Airport (PBC) flights
Questions & Answers
The cheapest way to get from Chicago to Cholula is to fly and bus which costs $2800 - $6500 and takes 9h 59m.
The fastest way to get from Chicago to Cholula is to fly which takes 9h 15m and costs $2300 - $9500.
No, there is no direct bus from Chicago station to Cholula. However, there are services departing from Chicago Bus Station and arriving at Puebla via 16th & Jackson NW, Omaha, Saltillo and Puebla, Central de Autobuses. The journey, including transfers, takes approximately 2 days 7h.
The distance between Chicago and Cholula is 2769 km. The road distance is 3211.9 km.
The best way to get from Chicago to Cholula without a car is to bus which takes 45h 38m and costs $5000 - $9500.
It takes approximately 9h 15m to get from Chicago to Cholula, including transfers.
Chicago to Cholula bus services, operated by Greyhound USA, depart from Chicago Bus Station.
The best way to get from Chicago to Cholula is to fly which takes 9h 15m and costs $2300 - $9500. Alternatively, you can bus, which costs $5000 - $9500 and takes 45h 38m.
Chicago to Cholula bus services, operated by Greyhound USA, arrive at Omaha, NE station.
Cholula is 1h behind Chicago. It is currently 1:42 AM in Chicago and 12:42 AM in Cholula.
What companies run services between Chicago, IL, USA and Cholula, Mexico?
Volaris, United Airlines, and three other airlines fly from Chicago O'Hare International Airport (ORD) to Hermanos Serdán International Airport (PBC) 5 times a day. Alternatively, you can take a subway from Roosevelt to Puebla via 35th/Archer, 35th/Archer Orange Line Station, California & 35th Street, Chicago, San Luis Potosí, San Luis Potosí, and Puebla, Central de Autobuses in around 45h 38m.
- Website
- volaris.com
Flights from Chicago O'Hare International Airport to Hermanos Serdán International Airport via Guadalajara
- Ave. Duration
- 6h 48m
- When
- Every day
- Estimated price
- $3,400–12,000
Flights from Chicago O'Hare International Airport to Hermanos Serdán International Airport via Houston
- Ave. Duration
- 6h 43m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $2,100–9,000
Flights from Chicago O'Hare International Airport to Hermanos Serdán International Airport via Cancun
- Ave. Duration
- 7h 15m
- When
- Every day
- Estimated price
- $2,600–11,000
Flights from Chicago Midway International Airport to Hermanos Serdán International Airport via Guadalajara
- Ave. Duration
- 11h 58m
- When
- Thursday and Saturday
- Estimated price
- $4,800–16,000
Flights from Chicago Midway International Airport to Hermanos Serdán International Airport via Cancun
- Ave. Duration
- 7h 43m
- When
- Monday, Thursday, Friday, Saturday, Sunday, and Wednesday
- Estimated price
- $3,700–15,000
Flights from Chicago O'Hare International Airport to Benito Juárez International Airport
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $2,400–6,000
Flights from Chicago Midway International Airport to Benito Juárez International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 35m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $4,100–14,000
Flights from Chicago O'Hare International Airport to Felipe Ángeles International Airport via Guadalajara
- Ave. Duration
- 7h 46m
- When
- Every day
- Estimated price
- $3,100–11,000
Flights from Chicago O'Hare International Airport to Felipe Ángeles International Airport via Cancun
- Ave. Duration
- 11h 13m
- When
- Every day
- Estimated price
- $2,400–10,000
- Website
- vivaaerobus.com
Flights from Chicago O'Hare International Airport to Hermanos Serdán International Airport via Monterrey
- Ave. Duration
- 7h 25m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $2,900–9,500
Flights from Chicago Midway International Airport to Hermanos Serdán International Airport via Guadalajara
- Ave. Duration
- 11h 51m
- When
- Thursday and Saturday
- Estimated price
- $4,800–16,000
Flights from Chicago O'Hare International Airport to Benito Juárez International Airport
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $2,800–5,500
Flights from Chicago O'Hare International Airport to Benito Juárez International Airport via Monterrey
- Ave. Duration
- 6h 10m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $2,800–5,500
Flights from Chicago Midway International Airport to Benito Juárez International Airport via San Antonio
- Ave. Duration
- 9h 5m
- When
- Saturday
- Estimated price
- $2,900–13,000
Flights from Chicago O'Hare International Airport to Felipe Ángeles International Airport via Monterrey
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $2,000–8,500
Flights from Chicago O'Hare International Airport to Felipe Ángeles International Airport via Guadalajara
- Ave. Duration
- 9h 15m
- When
- Every day
- Estimated price
- $3,000–9,500
Flights from Chicago O'Hare International Airport to Felipe Ángeles International Airport via Leon/Guanajuato
- Ave. Duration
- 6h 31m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- $2,900–10,000
- Website
- flyfrontier.com
Flights from Chicago O'Hare International Airport to Hermanos Serdán International Airport via Cancun
- Ave. Duration
- 7h 15m
- When
- Every day
- Estimated price
- $2,600–11,000
Flights from Chicago Midway International Airport to Hermanos Serdán International Airport via Cancun
- Ave. Duration
- 7h 43m
- When
- Monday, Thursday, Friday, Saturday, Sunday, and Wednesday
- Estimated price
- $3,700–15,000
Flights from Chicago O'Hare International Airport to Benito Juárez International Airport
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $2,400–6,000
Flights from Chicago Midway International Airport to Benito Juárez International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 35m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $4,100–14,000
Flights from Chicago O'Hare International Airport to Felipe Ángeles International Airport via Cancun
- Ave. Duration
- 11h 13m
- When
- Every day
- Estimated price
- $2,400–10,000
- Website
- united.com
Flights from Chicago O'Hare International Airport to Hermanos Serdán International Airport via Houston
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $2,100–9,000
Flights from Chicago O'Hare International Airport to Benito Juárez International Airport
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $2,000–9,000
Flights from Chicago O'Hare International Airport to Benito Juárez International Airport via Houston
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $2,000–9,000
- Website
- aeromexico.com
Flights from Chicago O'Hare International Airport to Benito Juárez International Airport
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $2,000–9,000
Flights from Chicago Midway International Airport to Benito Juárez International Airport via San Antonio
- Ave. Duration
- 5h 55m
- When
- Sunday
- Estimated price
- $2,900–13,000
Flights from Chicago Midway International Airport to Benito Juárez International Airport via Austin
- Ave. Duration
- 6h 5m
- When
- Saturday
- Estimated price
- $2,900–13,000
Flights from Chicago Midway International Airport to Benito Juárez International Airport via Leon/Guanajuato
- Ave. Duration
- 6h 11m
- When
- Tuesday and Thursday
- Estimated price
- $4,200–15,000
Flights from Chicago Midway International Airport to Benito Juárez International Airport via Zacatecas
- Ave. Duration
- 8h 2m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $4,300–15,000
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Benito Juárez International Airport
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $2,000–9,000
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to San Antonio Station
- Ave. Duration
- 32h 36m
- Frequency
- Once daily
- Estimated price
- $6,500–14,000
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to San Marcos Amtrak
- Ave. Duration
- 29h 58m
- Frequency
- Once daily
- Estimated price
- $6,000–14,000
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Chicago to San Luis Potosí
- Ave. Duration
- 35h 5m
- Frequency
- Once daily
- Estimated price
- $4,400–8,000
- Schedules at
- tornadobus.com
- Adults 11-59
- $4,400–8,000
- Phone
- +52 55 2643 9028
- Website
- apoloplatinum.com.mx
Bus from San Luis Potosí to Puebla
- Ave. Duration
- 6h 30m
- Frequency
- Twice daily
- Estimated price
- $650–1,000
- Schedules at
- apoloplatinum.com.mx
- Ejecutivo
- $650–900
- Confort
- $750–1,000
- Primera Clase
- $650–800
Bus from Saltillo to Puebla
- Ave. Duration
- 12h
- Frequency
- 3 times a day
- Estimated price
- $950–1,400
- Schedules at
- apoloplatinum.com.mx
- Ejecutivo
- $950–1,300
- Confort
- $1,000–1,400
- Primera Clase
- $1,000–1,200
- Phone
- +1 479 750 3263
- Website
- transporteschayo.com
Bus from San Antonio Station to Nuevo Laredo
- Ave. Duration
- 3h 14m
- Frequency
- Once daily
- Estimated price
- $900–1,000
- Schedules at
- transporteschayo.com
- Book at
- transporteschayo.com
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- futura.com.mx
Bus from Nuevo Laredo to Terminal Central Del Sur - Taxqueña
- Ave. Duration
- 8h 44m
- Frequency
- 3 times a day
- Estimated price
- $2,500–4,300
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
- Phone
- +52 55 4386 4652
- solucioneshola@ado.com.mx
- Website
- ado.com.mx
Bus from Terminal Central Del Sur - Taxqueña to Puebla Terminal CAPU
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $290–440
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 222 273 8300
- Website
- estrellaroja.com.mx
Bus from Terminal de Autobuses de Pasajeros de Oriente to Cholula 12 Poniente
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- $170–240
- Schedules at
- estrellaroja.com.mx
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Omaha, NE
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $1,200–2,400
- Website
- https://www.greyhound.com/
- Phone
- +52 449 913 0502
- tours.lopez@hotmail.com
- Website
- facebook.com
Bus from Omaha to Saltillo
- Ave. Duration
- 30h
- Frequency
- Twice a week
- Estimated price
- $4,200–4,900
- Schedules at
- facebook.com
- Phone
- +52 81 2152 6736
- info@conexionestornado.com
- Website
- tornadobus.com
Bus from Chicago to Morelia
- Ave. Duration
- 45h 25m
- Frequency
- Once daily
- Estimated price
- $4,700
- Website
- https://tornadobus.com/en/home/
- Phone
- +52 800 800 0386
- atn_clientes@etn.com.mx
- Website
- etn.com.mx
Bus from Morelia to Puebla CAPU
- Ave. Duration
- 5h 40m
- Frequency
- 5 times a day
- Estimated price
- $1,000–1,400
- Website
- https://etn.com.mx/english/
- Phone
- +1 800 923 1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from San Marcos to Terminal Central de Autobuses del Norte
- Ave. Duration
- 21h 17m
- Frequency
- Once daily
- Estimated price
- $2,400–3,900
- Schedules at
- omnibusexpress.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Mexico City Degollado to Puebla
- Ave. Duration
- 3h 5m
- Frequency
- Every 4 hours
- Estimated price
- $180–310
- Schedules at
- flixbus.com
Want to know more about travelling around Mexico
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More Questions & Answers
Yes, the driving distance between Chicago to Cholula is 3212 km. It takes approximately 35h 38m to drive from Chicago to Cholula.
There are 670+ hotels available in Cholula.











































