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How to get fromChicago to Cholulaby plane, bus (Flixbus), train, bus, car or bus (Greyhound)

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There are 10 ways to get from Chicago to Cholula by plane, bus (Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Hermanos Serdán International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Hermanos Serdán International Airport (PBC)plane plane ORD - PBC
    9h 35m
    $2,054–8,337

  2. Bus

    1. Take the bus from Chicago to Santiago de Querétarobus bus
    2. Take the bus from Querétaro to Mexico City Buenavistabus bus
    3. Take the bus from Mexico City Buenavista to Pueblabus bus
    47h 54m
    $5,364–9,484

  3. Train, bus via Nuevo Laredo

    1. Take the train from Chicago Union Station to San Antonio Stationtrain train
    2. Take the bus from San Antonio Station to Nuevo Laredobus bus
    3. Take the bus from Nuevo Laredo to Terminal Central Del Sur - Taxqueñabus bus
    4. Take the bus from Terminal Central Del Sur - Taxqueña to Puebla Terminal CAPUbus bus
    2d 3h
    $10,005–19,407

  4. Drive 3,211.9 km

    1. Drive from Chicago to Cholulacar car 3,211.9 km
    35h 38m
    $6,349–9,171

  5. Fly Chicago Midway International Airport to Hermanos Serdán International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Hermanos Serdán International Airport (PBC)plane plane MDW - PBC
    10h 7m
    $3,354–13,337

  6. Fly Chicago O'Hare International Airport to Benito Juárez International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Benito Juárez International Airport (MEX)plane plane ORD - MEX
    2. Take the bus from Terminal de Autobuses de Pasajeros de Oriente to Cholula 12 Ponientebus bus
    10h 15m
    $2,215–6,331

  7. Fly Chicago Midway International Airport to Benito Juárez International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Benito Juárez International Airport (MEX)plane plane MDW - MEX
    2. Take the bus from Terminal de Autobuses de Pasajeros de Oriente to Cholula 12 Ponientebus bus
    11h 48m
    $2,615–11,331

  8. Fly Chicago O'Hare International Airport to Felipe Ángeles International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Felipe Ángeles International Airport (NLU)plane plane ORD - NLU
    2. Take the bus from Mexico City Buenavista to Pueblabus bus
    13h 48m
    $2,342–7,964

  9. Bus via Omaha

    1. Take the bus from Chicago Bus Station to Omaha, NEbus bus
    2. Take the bus from Omaha to Saltillobus bus
    3. Take the bus from Saltillo to Pueblabus bus
    2d 7h
    $6,646–9,025

  10. Train, bus

    1. Take the train from Chicago Union Station to San Marcos Amtraktrain train
    2. Take the bus from San Marcos to Terminal Central de Autobuses del Nortebus bus
    3. Take the bus from Mexico City Degollado to Pueblabus bus
    2d 8h
    $8,562–17,244

Chicago O'Hare International Airport (ORD) to Hermanos Serdán International Airport (PBC) flights

Calendar35Weekly Planes
Duration8h 11mAverage Duration
Ticket$1,799Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Cholula, Mexico?

Viva Aerobus, United Airlines, and two other airlines fly from Chicago O'Hare International Airport (ORD) to Hermanos Serdán International Airport (PBC) 5 times a day. Alternatively, you can take a bus from State & Harrison/Ida B Wells Drive to Puebla via 35th/Archer Orange Line Station, California & 35th Street, Chicago, Santiago de Querétaro, Querétaro, and Mexico City Buenavista in around 47h 54m.

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