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How to get fromChicago to Cholulaby plane, bus (Flixbus), train, bus, car, or bus (Greyhound)

Find Transport to Cholula

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There are 9 ways to get from Chicago to Cholula by plane, bus (Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Hermanos Serdán International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Hermanos Serdán International Airport (PBC)plane plane ORD - PBC
    7h 20m
    $2,456–10,342

  2. Bus

    1. Take the bus from Chicago to Santiago de Querétarobus bus
    2. Take the bus from Querétaro to Mexico City Buenavistabus bus
    3. Take the bus from Mexico City Buenavista to Pueblabus bus
    2d 1h
    $5,793–9,219

  3. Train, bus via Nuevo Laredo

    1. Take the train from Chicago Union Station to San Antonio Stationtrain train
    2. Take the bus from San Antonio Station to Nuevo Laredobus bus
    3. Take the bus from Nuevo Laredo to Terminal Central Del Sur - Taxqueñabus bus
    4. Take the bus from Terminal Central Del Sur - Taxqueña to Puebla Terminal CAPUbus bus
    2d 3h
    $17,367–26,549

  4. Drive  3,211.9 km

    1. Drive from Chicago to Cholulacar car 3,211.9 km
    35h 39m
    $6,738–9,732

  5. Fly Chicago Midway International Airport to Hermanos Serdán International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Hermanos Serdán International Airport (PBC)plane plane MDW - PBC
    9h 49m
    $3,656–15,342

  6. Fly Chicago O'Hare International Airport to Benito Juárez International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Benito Juárez International Airport (MEX)plane plane ORD - MEX
    2. Take the bus from Terminal de Autobuses de Pasajeros de Oriente to Cholula 12 Ponientebus bus
    9h 58m
    $3,022–9,862

  7. Fly Chicago Midway International Airport to Benito Juárez International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Benito Juárez International Airport (MEX)plane plane MDW - MEX
    2. Take the bus from Terminal de Autobuses de Pasajeros de Oriente to Cholula 12 Ponientebus bus
    11h 33m
    $3,022–13,362

  8. Bus via Omaha

    1. Take the bus from Chicago Bus Station to Omaha, NEbus bus
    2. Take the bus from Omaha to Saltillobus bus
    3. Take the bus from Saltillo to Pueblabus bus
    2d 7h
    $7,746–8,974

  9. Train, bus

    1. Take the train from Chicago Union Station to San Marcos Amtraktrain train
    2. Take the bus from San Marcos to Terminal Central de Autobuses del Nortebus bus
    3. Take the bus from Mexico City Degollado to Pueblabus bus
    2d 8h
    $15,740–24,102

Chicago O'Hare International Airport (ORD) to Hermanos Serdán International Airport (PBC) flights

Calendar23Weekly Planes
Duration6h 8mAverage Duration
Ticket$2,260Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Cholula.ExpandLaunch map view
  • Distance: 2,768.9 km
  • Duration: 7h 20m

What companies run services between Chicago, IL, USA and Cholula, Mexico?

Volaris and United Airlines fly from Chicago O'Hare International Airport (ORD) to Hermanos Serdán International Airport (PBC) 3 times a day. Alternatively, you can take a subway from Harold Washington Library to Puebla via 35th/Archer, 35th/Archer Orange Line Station, California & 35th Street, Chicago, Santiago de Querétaro, Querétaro, and Mexico City Buenavista in around 2d 1h.

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Want to know more about travelling around Mexico

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