Explore 4 ways to travel

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Chicago Midway  •  4 h 13 min

  1. Fly from Chicago Midway (MDW) to Charleston (CHS) MDW - CHS

$197 - $629

Cheapest option

Bus Megabus  •  26 h 52 min

  1. Take the bus from Chicago to Marta Civic Center Station - Nb
  2. Take the bus from Atlanta, GA to Charleston, SC 0989

$109 - $162

5 alternative options

Fly from Chicago O'Hare  •  4 h 38 min

  1. Fly from Chicago O'Hare (ORD) to Charleston (CHS) ORD - CHS

$167 - $500

Bus Greyhound USA  •  24 h 38 min

  1. Take the bus from Chicago, Il to Atlanta, Ga
  2. Take the bus from Atlanta, Ga to Savannah, Ga
  3. Take the bus from Savannah, GA to Charleston, SC

$122 - $281

Train, bus  •  27 h 27 min

  1. Take the train from Chicago Union Station Amtrak to Toledo Amtrak
  2. Take the bus from Toledo, Oh to Columbia, Sc
  3. Take the bus from Columbia, SC to Charleston, SC

$141 - $329

Train, drive  •  30 h 7 min

  1. Take the train from Chicago Union Station Amtrak to Washington Union Station Amtrak
  2. Take the train from Washington Union Station Amtrak to Yemassee Amtrak
  3. Drive from Yemassee Amtrak to Charleston

$195 - $545

Drive  •  15 h 16 min

  1. Drive from Chicago to Charleston 916.2 miles

$85 - $130

What companies run services between Chicago, IL, USA and Charleston, SC, USA?

Southwest Airlines and Delta fly from Chicago to Charleston every 4 hours. Alternatively, you can take a bus from Chicago to Charleston via Atlanta, Ga, Savannah, Ga, Savannah, GA, Charleston, SC, and Rivers Ave / Cosgrove Ave in around 24 h 38 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to Charleston
Ave. Duration
2 h
When
Every day
Estimated price
$350 - $1,600
Flights from Chicago Midway to Charleston via Baltimore
Ave. Duration
4 h 22 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,600
Flights from Chicago Midway to Charleston via St. Louis
Ave. Duration
4 h 30 min
When
Monday, Tuesday, Wednesday and Thursday
Estimated price
$350 - $1,600
Flights from Chicago Midway to Charleston via Nashville
Ave. Duration
4 h 45 min
When
Monday to Saturday
Estimated price
$350 - $1,600
Delta
Website
delta.com
Flights from Chicago Midway to Charleston via Atlanta
Ave. Duration
4 h 32 min
When
Every day
Estimated price
$280 - $1,400
Flights from Chicago O'Hare to Charleston via Atlanta
Ave. Duration
4 h 21 min
When
Every day
Estimated price
$320 - $1,400
American Airlines
Website
aa.com
Flights from Chicago O'Hare to Charleston
Ave. Duration
2 h 25 min
When
Every day
Estimated price
$290 - $1,200
Flights from Chicago O'Hare to Charleston via Charlotte
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$290 - $1,200
United Airlines
Website
united.com
Flights from Chicago O'Hare to Charleston
Ave. Duration
2 h 12 min
When
Every day
Estimated price
$300 - $1,100
Flights from Chicago O'Hare to Charleston via Washington Dulles
Ave. Duration
4 h 19 min
When
Saturday
Estimated price
$300 - $1,100
Frontier Airlines
Website
flyfrontier.com
Flights from Chicago O'Hare to Charleston
Ave. Duration
2 h 14 min
When
Monday and Friday
Estimated price
$110 - $550
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Chicago Union Station Amtrak to Toledo Amtrak
Ave. Duration
3 h 59 min
Frequency
3 times a day
Estimated price
$45 - $120
Website
amtrak.com
Coach Seat
$45 - $70
Flexi Coach Seat
$80 - $120
Business Coach Seat
$80 - $120
Room
$210 - $300
Train from Chicago Union Station Amtrak to Washington Union Station Amtrak
Ave. Duration
17 h 25 min
Frequency
Once daily
Estimated price
$100 - $310
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $310
Room
$440 - $600
Train from Washington Union Station Amtrak to Yemassee Amtrak
Ave. Duration
10 h 18 min
Frequency
4 times a day
Estimated price
$80 - $230
Website
amtrak.com
Coach Seat
$80 - $120
Flexi Coach Seat
$140 - $210
Business Coach Seat
$160 - $230
Room
$340 - $480
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Chicago, Il to Atlanta, Ga
Ave. Duration
15 h 45 min
Frequency
Every 3 hours
Estimated price
$70 - $180
Website
greyhound.com
Economy
$70 - $120
Flexible
$130 - $180
Bus from Atlanta, Ga to Savannah, Ga
Ave. Duration
4 h 35 min
Frequency
Every 30 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Bus from Toledo, Oh to Columbia, Sc
Ave. Duration
18 h 55 min
Frequency
Hourly
Estimated price
$70 - $180
Website
greyhound.com
Economy
$70 - $120
Flexible
$130 - $180
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Savannah, GA to Charleston, SC
Ave. Duration
2 h 17 min
Frequency
Twice daily
Estimated price
$21 - $35
Schedules at
southeasternstages.com
Bus from Atlanta, GA to Charleston, SC
Ave. Duration
10 h 25 min
Frequency
Once daily
Estimated price
$45 - $75
Schedules at
southeasternstages.com
Bus from Columbia, SC to Charleston, SC
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$24 - $35
Schedules at
southeasternstages.com
Megabus

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Chicago and Charleston is 1218 km. The road distance is 1466 km.

The cheapest way to get from Chicago to Charleston is to drive which costs $85 - $130 and takes 15 h 16 min.

The quickest way to get from Chicago to Charleston is to fly which takes 4 h 13 min and costs $190 - $650.

No, there is no direct bus from Chicago to Charleston. However, there are services departing from Chicago, Il and arriving at Mary St / Meeting St via Atlanta, Ga, Savannah, GA and Rivers Ave / Cosgrove Ave. The journey, including transfers, takes approximately 24 h 38 min.

It takes approximately 4 h 13 min to get from Chicago to Charleston, including transfers.