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How to get fromChicago to Buffalo Central Terminalby plane, bus, bus (Greyhound, Flixbus), train (Amtrak) or car

Find Transport to Buffalo Central Terminal

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There are 7 ways to get from Chicago to Buffalo Central Terminal by plane, bus, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Buffalo Niagara International Airport, line 4 bus

    best
    1. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)planeMDW - BUF
    2. Take the bus from Ellicott Street MTC Static to Broadway Warren Avenue Eastbus
    5h 7m
    $118–477

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Cleveland Bus StationbusGreyhound US0164
    2. Take the bus from Cleveland, OH to Buffalo, NYbusCinncinati,OH-Buffalo
    12h 15m
    $54–143

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Buffalo Depew StationtrainLake Shore Limited
    12h 17m
    $55–159

  4. Drive 533.2 mi

    1. Drive from Chicago to Buffalo Central Terminalcar533.2 mi
    8h 59m
    $98–141

  5. Fly Chicago O'Hare International Airport to Buffalo Niagara International Airport, line 4 bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)planeORD - BUF
    2. Take the bus from Ellicott Street MTC Static to Broadway Warren Avenue Eastbus
    5h 32m
    $108–457

  6. Fly Chicago O'Hare International Airport to Rochester, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)planeORD - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus
    7h 40m
    $138–562

  7. Fly Chicago Midway International Airport to Rochester, bus

    1. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)planeMDW - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus
    7h 17m
    $118–692

Chicago to Buffalo Central Terminal by bus and foot

Calendar14Weekly Services
Duration12h 15mAverage Duration
Ticket$54Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Buffalo Central Terminal, NY, USA?

You can take a bus from Chicago Bus Station to Buffalo Central Terminal via Cleveland Bus Station, Cleveland, OH, Ellicott Street MTC Static, and Broadway Warren Avenue East in around 12h 15m. Alternatively, Amtrak operates a train from Chicago Union Station to Buffalo Depew Station twice daily. Tickets cost $50–160 and the journey takes 10h 23m.

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