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How to get fromChicago to Buffaloby plane, bus, train (Amtrak), car, or bus (Greyhound)

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There are 9 ways to get from Chicago to Buffalo by plane, bus, train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    4h 42m
    $178–333

  2. Bus

    cheapest
    1. Take the bus from Chicago to Clevelandbus bus Bsb 26
    2. Take the bus from Cleveland to Buffalobus bus Bsb 10
    11h 5m
    $52–139

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    11h 44m
    $293–586

  4. Drive  531.4 mi

    1. Drive from Chicago to Buffalocar car 531.4 mi
    9h 4m
    $97–141

  5. Fly Chicago Midway International Airport to Buffalo Niagara International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    4h 19m
    $168–403

  6. Fly Chicago O'Hare International Airport to Rochester, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)plane plane ORD - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 7m
    $132–697

  7. Fly Chicago Midway International Airport to Rochester, bus

    1. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane plane MDW - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 53m
    $182–997

  8. Fly Chicago O'Hare International Airport to Toronto Pearson International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Toronto Pearson International Airport (YYZ)plane plane ORD - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    8h 32m
    $408–1,029

  9. Bus via Brook Park (Greyhound)

    1. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus Greyhound US0164
    2. Take the bus from Cleveland Bus Station to Buffalobus bus Greyhound US0171 / ...
    11h 40m
    $96–146

Chicago to Buffalo by bus

Calendar7Weekly Buses
Duration11h 5mAverage Duration
Ticket$52Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Buffalo.ExpandLaunch map view
  • Distance: 499.6 mi
  • Duration: 4h 42m

What companies run services between Chicago, IL, USA and Buffalo, NY, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, you can take a bus from Chicago to Buffalo via Cleveland in around 11h 5m.

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