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There are 6 ways to get from Chicago to Buffalo by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Chicago Midway  •  3 h 39 min

  1. Fly from Chicago Midway (MDW) to Buffalo (BUF) MDW - BUF

$134 - $406

Cheapest option

Bus, Thru-Bus via Chicago, IL  •  15 h 19 min

  1. Take the bus from Chicago, IL to Hamilton, ON 5500
  2. Take the Thru-Bus from Hamilton, ON to Buffalo, NY 5591

$56 - $140

4 alternative options

Fly from Chicago O'Hare  •  4 h 4 min

  1. Fly from Chicago O'Hare (ORD) to Buffalo (BUF) ORD - BUF

$124 - $377

Train  •  11 h 29 min

  1. Take the train from Chicago Union Station to Buffalo Depew Station Lake Shore Limited

$98 - $250

Bus Greyhound USA, Thru-Bus  •  14 h 5 min

  1. Take the bus from Chicago, Il to Hamilton, On 5500
  2. Take the Thru-Bus from Hamilton, ON to Buffalo, NY 5591

$63 - $158

Drive  •  8 h 55 min

  1. Drive from Chicago to Buffalo 534.9 miles

$50 - $80

Questions & Answers

The cheapest way to get from Chicago to Buffalo is to drive which costs $50 - $80 and takes 8 h 55 min.

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The quickest way to get from Chicago to Buffalo is to fly which costs $130 - $410 and takes 3 h 39 min.

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No, there is no direct bus from Chicago to Buffalo. However, there are services departing from Chicago, Il and arriving at Buffalo, NY via Hamilton, ON. The journey, including transfers, takes approximately 14 h 5 min.

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No, there is no direct train from Chicago station to Buffalo station. However, there are services departing from Chicago Union Station and arriving at Buffalo Amtrak Station via Buffalo Depew Station. The journey, including transfers, takes approximately 11 h 29 min.

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The distance between Chicago and Buffalo is 454 miles. The road distance is 534.9 miles.

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The best way to get from Chicago to Buffalo without a car is to train which takes 11 h 29 min and costs $95 - $250.

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It takes approximately 3 h 39 min to get from Chicago to Buffalo, including transfers.

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Chicago to Buffalo bus services, operated by Greyhound USA, depart from Chicago, Il station.

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Chicago to Buffalo train services, operated by Amtrak, arrive at Chicago Union Station.

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The best way to get from Chicago to Buffalo is to fly which takes 3 h 39 min and costs $130 - $410. Alternatively, you can train, which costs $95 - $250 and takes 11 h 29 min, you could also bus and Thru-Bus, which costs $60 - $160 and takes 14 h 5 min.

Mode details

Map of how to get from Chicago to Buffalo.
Launch map view
  • Distance: 454.4 miles
  • Duration: 3 h 39 min

What companies run services between Chicago, IL, USA and Buffalo, NY, USA?

Southwest Airlines flies from Chicago to Buffalo 3 times a day. Alternatively, Amtrak operates a train from Chicago to Buffalo twice daily. Tickets cost $75 - $220 and the journey takes 10 h 16 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to Buffalo
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$160 - $750
United Airlines
Website
united.com
Flights from Chicago O'Hare to Buffalo
Ave. Duration
1 h 38 min
When
Every day
Estimated price
$140 - $750
Flights from Chicago O'Hare to Buffalo via Washington Dulles
Ave. Duration
3 h 53 min
When
Wednesday
Estimated price
$140 - $750
American Airlines
Website
aa.com
Flights from Chicago O'Hare to Buffalo
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$120 - $650
Delta
Website
delta.com
Flights from Chicago O'Hare to Buffalo via Detroit
Ave. Duration
3 h 52 min
When
Saturday
Estimated price
$130 - $800
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Chicago Union Station to Buffalo Depew Station
Ave. Duration
10 h 16 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Chicago, Il to Hamilton, On
Ave. Duration
10 h 25 min
Frequency
Once daily
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $80
Flexible
$95 - $130
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Hamilton, ON to Buffalo, NY
Ave. Duration
2 h 40 min
Frequency
Once daily
Estimated price
$12 - $35
Website
Greyhound.ca
Advanced Purchase
$12 - $18
Online Fare
$13 - $27
Standard Fare
$21 - $35
Refundable
$25 - $40
Bus from Chicago, IL to Hamilton, ON
Ave. Duration
11 h 39 min
Frequency
Once daily
Estimated price
$40 - $110
Website
Greyhound.ca
Advanced Purchase
$40 - $65
Online Fare
$55 - $85
Standard Fare
$70 - $110
Refundable
$80 - $120

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Chicago Midway Airport to Buffalo Airport is the direct flight which takes 1 h 20 min.

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Chicago to Buffalo bus services, operated by Greyhound Canada, arrive at Buffalo, NY station.

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Buffalo is 1 h ahead of Chicago. It is currently 3:26 PM in Chicago and 4:26 PM in Buffalo.

Chicago to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.

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Yes, the driving distance between Chicago to Buffalo is 535 miles. It takes approximately 8 h 55 min to drive from Chicago to Buffalo.

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Southwest Airlines offers flights from Chicago Midway Airport to Buffalo Airport.

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Book your Chicago to Buffalo train tickets online with Rome2rio.

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Book your Chicago to Buffalo bus tickets online with Busbud and Busbud.

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There are 141+ hotels available in Buffalo. Prices start at $62 USD per night.

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The best way to get from Chicago to Chicago Midway Airport is to subway which takes 23 min and costs $2 - $4.

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