There are 7 ways to get from Chicago to Buffalo by plane, bus, train (Amtrak), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago Midway International Airport to Buffalo Niagara International Airport
best- Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane MDW - BUF
4h 3m$208–1,333Bus
cheapest- Take the bus from Chicago to Clevelandbus Chicago
- Take the bus from Cleveland, OH to Buffalo, NYbus Cinncinati,OH-Buffalo
11h 5m$52–139Train (Amtrak)
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain Lake Shore Limited
11h 44m$151–382Drive 531.4 mi
- Drive from Chicago to Buffalocar 531.4 mi
9h 4m$97–141Fly Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane ORD - BUF
4h 36m$148–933Fly Chicago Midway International Airport to Rochester, bus
- Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane MDW - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
5h 28m$140–750Bus via Brook Park (Greyhound)
- Take the bus from Chicago Bus Station to Cleveland Bus Stationbus Greyhound US0164
- Take the bus from Cleveland Bus Station to Buffalobus Greyhound US0171 / ...
11h 40m$85–169
Chicago to Buffalo by bus
Questions & Answers
The cheapest way to get from Chicago to Buffalo is to bus via Brook Park which costs $85 - $170 and takes 11h 40m.
The fastest way to get from Chicago to Buffalo is to fly which takes 4h 3m and costs $200 - $1,400.
No, there is no direct bus from Chicago to Buffalo. However, there are services departing from Chicago and arriving at Buffalo, NY via Cleveland, OH. The journey, including transfers, takes approximately 11h 5m.
No, there is no direct train from Chicago station to Buffalo. However, there are services departing from Chicago Union Station and arriving at Buffalo via Buffalo Depew Station. The journey, including transfers, takes approximately 11h 44m.
The distance between Chicago and Buffalo is 489 miles. The road distance is 534.6 miles.
The best way to get from Chicago to Buffalo without a car is to bus which takes 11h 5m and costs $50 - $140.
It takes approximately 4h 3m to get from Chicago to Buffalo, including transfers.
Chicago to Buffalo bus services, operated by Barons Bus, depart from Chicago station.
Chicago to Buffalo train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Buffalo is to fly which takes 4h 3m and costs $200 - $1,400. Alternatively, you can bus, which costs $50 - $140 and takes 11h 5m, you could also train, which costs $150 - $390 and takes 11h 44m.
What companies run services between Chicago, IL, USA and Buffalo, NY, USA?
Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, you can take a bus from Chicago to Buffalo, NY via Cleveland, OH in around 11h 5m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $200–1,300
Flights from Chicago Midway International Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $110–700
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $140–900
- Website
- united.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $140–900
- Website
- delta.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- $200–1,300
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $140–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $140–310
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Chicago to Cleveland
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- $9–16
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Buffalo
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Chicago to Buffalo bus services, operated by Barons Bus, arrive at Cleveland station.
Buffalo is 1h ahead of Chicago. It is currently 6:43 AM in Chicago and 7:43 AM in Buffalo.
Chicago to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Chicago to Buffalo is 535 miles. It takes approximately 9h 4m to drive from Chicago to Buffalo.
Book your Chicago to Buffalo train tickets online with Omio.
Book your Chicago to Buffalo bus tickets online with Omio.
There are 573+ hotels available in Buffalo.