There are 6 ways to get from Chicago to Buffalo by subway, plane, bus (Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Chicago Midway International Airport, fly to Buffalo Niagara International Airport
best- Take the subway from Roosevelt to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane MDW - BUF
3h 55m$184–1,207Bus
cheapest- Take the bus from Chicago Bus Station to Cleveland Bus Stationbus Greyhound US0164
- Take the bus from Cleveland, OH to Buffalo, NYbus Cinncinati,OH-Buffalo
11h 20m$64–144Train (Amtrak)
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain Lake Shore Limited
11h 44m$152–383Drive 532.1 mi
- Drive from Chicago to Buffalocar 532.1 mi
9h 2m$98–141Fly Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane ORD - BUF
4h 25m$134–807Fly Chicago Midway International Airport to Rochester, bus
- Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane MDW - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
5h 26m$130–701
Chicago to Buffalo by bus
Questions & Answers
The cheapest way to get from Chicago to Buffalo is to bus which costs $60 - $150 and takes 11h 20m.
The fastest way to get from Chicago to Buffalo is to subway and fly which takes 3h 55m and costs $180 - $1,300.
No, there is no direct bus from Chicago station to Buffalo. However, there are services departing from Chicago Bus Station and arriving at Buffalo, NY via Cleveland, OH. The journey, including transfers, takes approximately 11h 20m.
No, there is no direct train from Chicago station to Buffalo. However, there are services departing from Chicago Union Station and arriving at Buffalo via Buffalo Depew Station. The journey, including transfers, takes approximately 11h 44m.
The distance between Chicago and Buffalo is 494 miles. The road distance is 535.2 miles.
The best way to get from Chicago to Buffalo without a car is to bus which takes 11h 20m and costs $60 - $150.
It takes approximately 3h 55m to get from Chicago to Buffalo, including transfers.
Chicago to Buffalo bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Buffalo train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Buffalo is to bus which takes 11h 20m and costs $60 - $150. Alternatively, you can train, which costs $150 - $390 and takes 11h 44m, you could also fly, which costs $130 - $850 and takes 4h 25m.
What companies run services between Chicago, IL, USA and Buffalo, NY, USA?
You can take a bus from Chicago Bus Station to Buffalo, NY via Cleveland Bus Station and Cleveland, OH in around 11h 20m. Alternatively, Amtrak operates a train from Chicago Union Station to Buffalo Depew Station twice daily. Tickets cost $140–310 and the journey takes 10h 23m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $180–1,200
Flights from Chicago Midway International Airport to Rochester
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $100–650
Flights from Chicago Midway International Airport to Rochester via Baltimore
- Ave. Duration
- 3h 55m
- When
- Monday to Friday
- Estimated price
- $150–800
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $130–800
- Website
- united.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $130–800
- Website
- delta.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $180–1,200
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $130–800
Flights from Chicago Midway International Airport to Rochester via Detroit
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $100–650
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Roosevelt to Midway
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $140–310
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Chicago Bus Station to Cleveland Bus Station
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $9–16
- Schedules at
- flixbus.com
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More Questions & Answers
Chicago to Buffalo bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Buffalo is 1h ahead of Chicago. It is currently 1:57 AM in Chicago and 2:57 AM in Buffalo.
Chicago to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Chicago to Buffalo is 535 miles. It takes approximately 9h 2m to drive from Chicago to Buffalo.
Book your Chicago to Buffalo train tickets online with Omio.
Book your Chicago to Buffalo bus tickets online with Omio and FlixBus.
There are 571+ hotels available in Buffalo.