There are 6 ways to get from Chicago to 21st & Main by train, bus, bus (Flixbus), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Chicago Union Station to Milwaukeetrain Hiawatha Service / ...
- Take the bus from Milwaukee to Fond du Lacbus Milwaukee
3h 50m$40–69Bus (Flixbus)
cheapest- Take the bus from Chicago Bus Station to Fond Du Lacbus FlixBus 2550
3h 57m$19–35Drive 148 mi
- Drive from Chicago to 21st & Maincar 148 mi
2h 48m$27–39Fly Chicago O'Hare International Airport to Appleton International Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Appleton International Airport (ATW)plane ORD - ATW
- Take the bus from Appleton to Fond du Lacbus
5h 34m$86–466Fly Chicago O'Hare International Airport to General Mitchell International Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to General Mitchell International Airport (MKE)plane ORD - MKE
- Take the bus from Milwaukee Airport to Fond du Lacbus
5h 37m$66–436Fly Chicago Midway International Airport to General Mitchell International Airport, bus
- Fly from Chicago Midway International Airport (MDW) to General Mitchell International Airport (MKE)plane MDW - MKE
- Take the bus from Milwaukee Airport to Fond du Lacbus
5h 7m$86–626
Chicago to 21st & Main by train, bus, and foot
Questions & Answers
The cheapest way to get from Chicago to 21st & Main is to bus which costs $19 - $35 and takes 3h 57m.
The fastest way to get from Chicago to 21st & Main is to drive which takes 2h 48m and costs $27 - $40.
Yes, there is a direct bus departing from Chicago Bus Station station and arriving at Fond Du Lac. Services depart five times a week, and operate Monday, Thursday, Friday, Saturday and Sunday. The journey takes approximately 3h 30m.
The distance between Chicago and 21st & Main is 146 miles. The road distance is 148.9 miles.
The best way to get from Chicago to 21st & Main without a car is to train and bus which takes 3h 50m and costs $40 - $70.
It takes approximately 3h 50m to get from Chicago to 21st & Main, including transfers.
Chicago to 21st & Main bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to 21st & Main bus services, operated by Flixbus USA, arrive at Fond Du Lac station.
Yes, the driving distance between Chicago to 21st & Main is 149 miles. It takes approximately 2h 48m to drive from Chicago to 21st & Main.
There are 70+ hotels available in 21st & Main.
What companies run services between Chicago, IL, USA and 21st & Main, WI, USA?
Flixbus USA operates a bus from Chicago Bus Station to Fond Du Lac 5 times a week. Tickets cost $19–35 and the journey takes 3h 30m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Appleton International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $50–420
Flights from Chicago O'Hare International Airport to General Mitchell International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $45–410
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Appleton International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $50–420
Flights from Chicago O'Hare International Airport to General Mitchell International Airport
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- $45–410
- Website
- southwest.com
Flights from Chicago Midway International Airport to General Mitchell International Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- $65–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $23–50
- Website
- https://www.amtrak.com/home.html
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Milwaukee to Fond du Lac
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $17–19
- Schedules at
- golamers.com
Bus from Appleton to Fond du Lac
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $14–17
- Schedules at
- golamers.com
Bus from Milwaukee Airport to Fond du Lac
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $18–21
- Schedules at
- golamers.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago Bus Station to Fond Du Lac
- Ave. Duration
- 3h 30m
- Frequency
- 5 times a week
- Estimated price
- $19–35
- Schedules at
- flixbus.com
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