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How to get fromChicago Station (CTA Logan Square branch) to Buffalo Depew Stationby bus, subway, plane, train (Amtrak) or car

Find Transport to Buffalo Depew Station

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There are 6 ways to get from Chicago Station (CTA Logan Square branch) to Buffalo Depew Station by bus, subway, plane, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 9 bus, subway to Chicago Midway International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from Ashland & Chicago to Ashland Orange Line Stationbus
    2. Take the subway from Ashland-Orange to Midwaysubway
    3. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)planeMDW - BUF
    3h 28m
    $195–1,120
  2. Train (Amtrak)

    cheapest
    1. Take the train from Chicago Union Station to Buffalo Depew StationtrainLake Shore Limited
    12h 11m
    $60–185
  3. Drive 538 mi

    1. Drive from Chicago Station (CTA Logan Square branch) to Buffalo Depew Stationcar538 mi
    9h 2m
    $99–142
  4. Fly Chicago O'Hare International Airport to Buffalo Niagara International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)planeORD - BUF
    3h 35m
    $166–923
  5. Fly Chicago O'Hare International Airport to Rochester, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)planeORD - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus
    5h 42m
    $166–539
  6. Fly Chicago Midway International Airport to Rochester, bus

    1. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)planeMDW - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus
    5h 38m
    $120–576

Chicago Station (CTA Logan Square branch) to Buffalo Depew Station by bus and train (Amtrak)

Calendar14Weekly Services
Duration12h 11mAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

What companies run services between Chicago Station (CTA Logan Square branch), IL, USA and Buffalo Depew Station, NY, USA?

Amtrak operates a train from Chicago Union Station to Buffalo Depew Station twice daily. Tickets cost $55–180 and the journey takes 10h 23m. Alternatively, American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF) every 3 hours.

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