There are 6 ways to get from Chicago Midway Airport (MDW) to St. Louis by plane, subway, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Chicago Midway  •  1 h 46 min

  1. Fly from Chicago Midway (MDW) to St. Louis (STL) MDW - STL

$132 - $300

Cheapest option

Bus Megabus  •  7 h 42 min

  1. Take the bus from Chicago, IL to St. Louis via St Louis

$31 - $44

4 alternative options

Subway to Chicago O'Hare, fly  •  3 h 55 min

  1. Take the subway from Midway to Harold Washington Library
  2. Fly from Chicago O'Hare (ORD) to St. Louis (STL) ORD - STL

$92 - $252

Bus Greyhound USA  •  6 h 12 min

  1. Take the bus from Chicago Midway Airport to Champaign - Illinois Terminal Chicago Area to Champaing SOUTH
  2. Take the bus from Champaign, Il to St Louis, Mo 1163 / ...

$48 - $85

Train  •  7 h 6 min

  1. Take the train from Chicago Union Station to St. Louis Gateway Station Lincoln Service / ...

$52 - $134

Drive  •  4 h 46 min

  1. Drive from Chicago Midway Airport (MDW) to St. Louis 290 miles

$28 - $45

Questions & Answers

No, there is no direct bus from Chicago Midway Airport (MDW) to St. Louis. However, there are services departing from Chicago Midway Airport and arriving at St Louis, Mo via Champaign, Il. The journey, including transfers, takes approximately 6 h 12 min.

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The distance between Chicago Midway Airport (MDW) and St. Louis is 255 miles. The road distance is 290 miles.

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The best way to get from Chicago Midway Airport (MDW) to St. Louis without a car is to bus which takes 6 h 12 min and costs .

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It takes approximately 1 h 46 min to get from Chicago Midway Airport (MDW) to St. Louis, including transfers.

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Chicago Midway Airport (MDW) to St. Louis bus services, operated by Peoria Charter Coach Company, depart from Chicago Midway Airport station.

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The best way to get from Chicago Midway Airport (MDW) to St. Louis is to fly which takes 1 h 46 min and costs . Alternatively, you can bus, which costs and takes 6 h 12 min, you could also train, which costs and takes 7 h 6 min.

Mode details

The quickest flight from Chicago Midway Airport to St. Louis Airport is the direct flight which takes 1 h 5 min.

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Chicago Midway Airport (MDW) to St. Louis bus services, operated by Greyhound USA, arrive at St Louis, Mo station.

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Yes, the driving distance between Chicago Midway Airport (MDW) to St. Louis is 290 miles. It takes approximately 4 h 46 min to drive from Chicago Midway Airport (MDW) to St. Louis.

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Southwest Airlines offers flights from Chicago Midway Airport to St. Louis Airport.

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Map of how to get from Chicago Midway Airport (MDW) to St. Louis.
Launch map view
  • Distance: 255.4 miles
  • Duration: 1 h 46 min

What companies run services between Chicago Midway Airport (MDW), USA and St. Louis, MO, USA?

Southwest Airlines flies from Chicago Midway Airport (MDW) to St. Louis every 4 hours. Alternatively, you can take a bus from Chicago Midway Airport (MDW) to St. Louis via Champaign - Illinois Terminal and Champaign, Il in around 6 h 12 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to St. Louis
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$160 - $550
United Airlines
Website
united.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 19 min
When
Every day
Estimated price
$120 - $650
American Airlines
Website
aa.com
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 9 min
When
Every day
Estimated price
$120 - $550
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Chicago Union Station to St. Louis Gateway Station
Ave. Duration
5 h 30 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Peoria Charter Coach Company
Website
peoriacharter.com
Bus from Chicago Midway Airport to Champaign - Illinois Terminal
Ave. Duration
2 h 25 min
Frequency
3 times a day
Estimated price
$25 - $30
Schedules at
peoriacharter.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Champaign, Il to St Louis, Mo
Ave. Duration
3 h 35 min
Frequency
Every 30 minutes
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $40
Flexible
$40 - $55

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There are 193+ hotels available in St. Louis. Prices start at $70 USD per night.

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