There are 5 ways to get from Chicago Loop to Sikeston by plane, taxi, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Cape Girardeau Municipal Airport, taxi
best- Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)ORD - CGI
- Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikeston
3h 48m$158–260Drive 395.6 mi
cheapest- Drive from Chicago Loop to Sikeston395.6 mi
6h 28m$73–105Train, taxi (Amtrak)
- Take the train from Chicago Union Station to Fulton Amtrak StationCity of New Orleans
- Take the taxi from Fulton Amtrak Station to Sikeston
8h 38m$213–286Bus
- Take the bus from Tornado Bus Co - Chicago to Flying J - MatthewsMilwaukee
9h 20m$100–221Fly to Williamson County Regional Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)ORD - MWA
- Take the bus from Marathon Gas Station - Marion to Flying J - Matthews
6h$134–355
Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights
Questions & Answers
The cheapest way to get from Chicago Loop to Sikeston is to drive which costs $70 - $110 and takes 6h 28m.
The fastest way to get from Chicago Loop to Sikeston is to fly and taxi which takes 3h 48m and costs $150 - $260.
The distance between Chicago Loop and Sikeston is 388 miles. The road distance is 397.9 miles.
The best way to get from Chicago Loop to Sikeston without a car is to train and taxi which takes 8h 38m and costs $210 - $290.
It takes approximately 3h 48m to get from Chicago Loop to Sikeston, including transfers.
Yes, the driving distance between Chicago Loop to Sikeston is 398 miles. It takes approximately 6h 28m to drive from Chicago Loop to Sikeston.
There are 14+ hotels available in Sikeston.
What companies run services between Chicago Loop, IL, USA and Sikeston, MO, USA?
Tornado Bus Company operates a bus from Tornado Bus Co - Chicago to Flying J - Matthews once daily. Tickets cost $75–190 and the journey takes 7h 24m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Cape Girardeau Municipal Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $85–170
Flights from Chicago O'Hare International Airport to Williamson County Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $60–170
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Fulton Amtrak Station
- Ave. Duration
- 7h 7m
- Frequency
- Once daily
- Estimated price
- $70–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Tornado Bus Co - Chicago to Flying J - Matthews
- Ave. Duration
- 7h 24m
- Frequency
- Once daily
- Estimated price
- $75–190
- Schedules at
- tornadobus.com
- Adults 11-59
- $75–190
Bus from Marathon Gas Station - Marion to Flying J - Matthews
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
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