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How to get fromChicago Loop to Sikestonby plane, taxi, train, car, or bus

Find Transport to Sikeston

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There are 6 ways to get from Chicago Loop to Sikeston by plane, taxi, train, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cape Girardeau Municipal Airport, taxi

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    3h 49m
    $182–465

  2. Fly to Barkley Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    4h 20m
    $52–300

  3. Train, drive (Amtrak)

    1. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train City of New Orleans
    2. Drive from Fulton Amtrak Station to Sikestoncar car
    9h 16m
    $235–362

  4. Bus

    1. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    9h 17m
    $112–142

  5. Drive  395.6 mi

    1. Drive from Chicago Loop to Sikestoncar car 395.6 mi
    6h 32m
    $73–105

  6. Fly to Williamson County Regional Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    2. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    6h
    $138–306

Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights

Calendar7Weekly Planes
Duration1h 35mAverage Duration
Ticket$102Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Chicago Loop to Sikeston.ExpandLaunch map view
  • Distance: 386.2 mi
  • Duration: 3h 49m

What companies run services between Chicago Loop, IL, USA and Sikeston, MO, USA?

Tornado Bus Company operates a bus from Tornado Bus Co - Chicago to Flying J - Matthews once daily. Tickets cost $80–100 and the journey takes 7h 24m.

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