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How to get fromChicago Loop to Pittsburghby plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, train or bus (Flixbus)

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There are 8 ways to get from Chicago Loop to Pittsburgh by plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Pittsburgh International Airport, bus

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Pittsburgh International Airport (PIT)plane plane ORD - PIT
    2. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    4h 49m
  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164
    10h 10m
    $55–120
  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    9h 25m
    $90–200
  4. Drive 460.6 mi

    1. Drive from Chicago Loop to Pittsburghcar car 460.6 mi
    7h 32m
    $85–122
  5. Fly Chicago Midway International Airport to Pittsburgh International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Pittsburgh International Airport (PIT)plane plane MDW - PIT
    2. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    4h 37m
  6. Fly Chicago O'Hare International Airport to Johnstown-Cambria County Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Johnstown-Cambria County Airport (JST)plane plane ORD - JST
    2. Take the train from Johnstown Amtrak Station to Pittsburgh Amtrak Stationtrain train
    6h 35m
    $84–355
  7. Fly Chicago O'Hare International Airport to Morgantown Municipal Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Morgantown Municipal Airport (MGW)plane plane ORD - MGW
    2. Take the bus from Mountaineer Station to Pittsburgh Greyhoundbus bus
    6h 47m
    $66–349
  8. Bus via Chicago (Flixbus)

    1. Take the bus from Chicago to Pittsburgh Intermodal Stationbus bus FlixBus N2640
    12h 3m
    $62–115

Chicago Loop to Pittsburgh by train (Amtrak)

Calendar7Weekly Trains
Duration9h 25mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

What companies run services between Chicago Loop, IL, USA and Pittsburgh, PA, USA?

Amtrak operates a train from Chicago Union Station to Pittsburgh Amtrak Station once daily. Tickets cost $90–200 and the journey takes 9h 25m. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Pittsburgh Intermodal Station twice daily. Tickets cost $55–120 and the journey takes 10h 10m. Flixbus USA also services this route once daily.

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