There are 8 ways to get from Chicago Loop to Pittsburgh by plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago Midway International Airport to Pittsburgh International Airport, bus
best- Fly from Chicago Midway International Airport (MDW) to Pittsburgh International Airport (PIT)MDW - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
4h 24mBus
cheapest- Take the bus from Chicago Bus Station to Pittsburgh Intermodal StationGreyhound US0164
10h 10m$60–130Train (Amtrak)
- Take the train from Chicago Union Station to Pittsburgh Amtrak StationFloridian
9h 25m$90–200Drive 460.6 mi
- Drive from Chicago Loop to Pittsburgh460.6 mi
7h 32m$85–122Fly Chicago O'Hare International Airport to Pittsburgh International Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Pittsburgh International Airport (PIT)ORD - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
4h 37mFly Chicago O'Hare International Airport to Johnstown-Cambria County Airport, train
- Fly from Chicago O'Hare International Airport (ORD) to Johnstown-Cambria County Airport (JST)ORD - JST
- Take the train from Johnstown Amtrak Station to Pittsburgh Amtrak Station
6h 26m$84–334Fly Chicago O'Hare International Airport to Morgantown Municipal Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Morgantown Municipal Airport (MGW)ORD - MGW
- Take the bus from Mountaineer Station to Pittsburgh Greyhound
6h 41m$62–339Bus via Chicago (Flixbus)
- Take the bus from Chicago to Pittsburgh Intermodal StationFlixBus N2640
12h 3m$62–115
Chicago Loop to Pittsburgh by train (Amtrak)
Questions & Answers
The cheapest way to get from Chicago Loop to Pittsburgh is to bus which costs $60 - $130 and takes 10h 10m.
The fastest way to get from Chicago Loop to Pittsburgh is to fly and train which takes 6h 26m and costs $80 - $340.
Yes, there is a direct bus departing from Chicago Bus Station station and arriving at Pittsburgh Intermodal Station station. Services depart three times a day, and operate every day. The journey takes approximately 10h 10m.
Yes, there is a direct train departing from Chicago Union Station station and arriving at Pittsburgh Amtrak Station station. Services depart once daily, and operate every day. The journey takes approximately 9h 25m.
The distance between Chicago Loop and Pittsburgh is 439 miles. The road distance is 463.3 miles.
The best way to get from Chicago Loop to Pittsburgh without a car is to train which takes 9h 25m and costs $90 - $200.
It takes approximately 4h 24m to get from Chicago Loop to Pittsburgh, including transfers.
Chicago Loop to Pittsburgh bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago Loop to Pittsburgh train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago Loop to Pittsburgh is to train which takes 9h 25m and costs $90 - $200. Alternatively, you can bus, which costs $60 - $130 and takes 10h 10m.
What companies run services between Chicago Loop, IL, USA and Pittsburgh, PA, USA?
Amtrak operates a train from Chicago Union Station to Pittsburgh Amtrak Station once daily. Tickets cost $90–200 and the journey takes 9h 25m. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Pittsburgh Intermodal Station twice daily. Tickets cost $60–130 and the journey takes 10h 10m. Flixbus USA also services this route once daily.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- united.com
Flights from Chicago O'Hare International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $50–300
Flights from Chicago O'Hare International Airport to Johnstown-Cambria County Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $50–290
Flights from Chicago O'Hare International Airport to Johnstown-Cambria County Airport via Washington Dulles
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $60–330
Flights from Chicago O'Hare International Airport to Morgantown Municipal Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $45–290
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $50–300
- Website
- southwest.com
Flights from Chicago Midway International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $60–360
- Website
- delta.com
Flights from Chicago Midway International Airport to Pittsburgh International Airport via Detroit
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $60–370
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $90–200
- Website
- https://www.amtrak.com/home.html
Train from Johnstown Amtrak Station to Pittsburgh Amtrak Station
- Ave. Duration
- 1h 51m
- Frequency
- Once daily
- Estimated price
- $18–21
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 412-442-2000
- Website
- rideprt.org
Bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Website
- https://www.rideprt.org
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 10h 10m
- Frequency
- Twice daily
- Estimated price
- $60–130
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 11h
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- flixbus.com
Bus from Chicago to Pittsburgh Intermodal Station
- Ave. Duration
- 10h 35m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
- Adult
- $60–110
- Phone
- +1 304-291-7433
- Website
- busride.org
Bus from Mountaineer Station to Pittsburgh Greyhound
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $3–30
- Website
- https://www.busride.org
Want to know more about travelling around United States
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More Questions & Answers
Chicago Loop to Pittsburgh bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Pittsburgh is 1h ahead of Chicago Loop. It is currently 9:57 AM in Chicago Loop and 10:57 AM in Pittsburgh.
Chicago Loop to Pittsburgh train services, operated by Amtrak, arrive at Pittsburgh Amtrak Station.
Yes, the driving distance between Chicago Loop to Pittsburgh is 463 miles. It takes approximately 7h 32m to drive from Chicago Loop to Pittsburgh.
Book your Chicago Loop to Pittsburgh train tickets online with Omio.
Book your Chicago Loop to Pittsburgh bus tickets online with Omio and FlixBus.
There are 688+ hotels available in Pittsburgh.







