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How to get fromChicago Loop to Memphisby subway, plane, bus (Greyhound, Flixbus), car, train, bus, or bus (Flixbus)

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There are 6 ways to get from Chicago Loop to Memphis by subway, plane, bus (Greyhound, Flixbus), car, train, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to Chicago Midway International Airport, fly

    best
    1. Take the subway from Clark/Lake to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Memphis (MEM)plane plane MDW - MEM
    4h 39m
    $154–956

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus Greyhound US0125
    10h 52m
    $87–144

  3. Drive  532.5 mi

    1. Drive from Chicago Loop to Memphiscar car 532.5 mi
    8h 37m
    $98–141

  4. Fly from Chicago O'Hare International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Memphis (MEM)plane plane ORD - MEM
    4h 59m
    $104–606

  5. Train, bus

    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    2. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus Greyhound US1173
    12h 36m
    $201–318

  6. Bus via Champaign

    1. Take the bus from Downtown Chicago to Illinois Terminalbus bus Chicago Area to Champaign SOUTH
    2. Take the bus from Champaign Intermodal Trans Ctr to Memphis Bus Stationbus bus FlixBus 2510
    13h 32m
    $98–153

Chicago Loop to Memphis by bus

Calendar12Weekly Buses
Duration10h 52mAverage Duration
Ticket$87Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago Loop to Memphis.ExpandLaunch map view
  • Distance: 506.3 mi
  • Duration: 4h 39m

What companies run services between Chicago Loop, IL, USA and Memphis, TN, USA?

Greyhound USA operates a bus from Chicago Bus Station to Memphis Bus Station once daily. Tickets cost $95–150 and the journey takes 9h 35m. Flixbus USA also services this route 5 times a week. Alternatively, American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Memphis (MEM) every 2 hours.

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Need to know: Greyhound

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