There are 5 ways to get from Chicago Loop to Indianapolis by bus (Flixbus, Greyhound, Amtrak), train (Amtrak), car, plane, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Chicago Bus Station to Indianapolisbus FlixBus 2511 / ...
3h 45m$30–50Train (Amtrak)
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
4h 54m$100–170Drive 179.5 mi
- Drive from Chicago Loop to Indianapoliscar 179.5 mi
3h 13m$33–48Fly from Chicago O'Hare International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Indianapolis (IND)plane ORD - IND
3h 52m$354–857Subway to Chicago Midway International Airport, fly
- Take the subway from Clark/Lake to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Indianapolis (IND)plane MDW - IND
3h 39m$74–557
Chicago Loop to Indianapolis by bus
Comparing Your Travel Options
The cheapest way to get from Chicago Loop to Indianapolis is to bus which costs $30 - $50 and takes 3h 45m.
The fastest way to get from Chicago Loop to Indianapolis is to drive which takes 3h 13m and costs $30 - $50.
Yes, there is a direct bus departing from Chicago Bus Station station and arriving at Indianapolis. Services depart every four hours, and operate every day. The journey takes approximately 3h 45m.
Yes, there is a direct train departing from Chicago Union Station station and arriving at Indianapolis. Services depart three times a week, and operate Tuesday, Thursday and Saturday. The journey takes approximately 4h 54m.
The distance between Chicago Loop and Indianapolis is 184 miles. The road distance is 180.6 miles.
The best way to get from Chicago Loop to Indianapolis without a car is to bus which takes 3h 45m and costs $30 - $50.
The bus from Chicago Bus Station to Indianapolis takes 3h 45m including transfers and departs every four hours.
Chicago Loop to Indianapolis bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago Loop to Indianapolis train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago Loop to Indianapolis is to bus which takes 3h 45m and costs $30 - $50. Alternatively, you can train, which costs $100 - $170 and takes 4h 54m, you could also fly, which costs $350 - $900 and takes 3h 52m.
What companies run services between Chicago Loop, IL, USA and Indianapolis, IN, USA?
Flixbus USA operates a bus from Chicago Bus Station to Indianapolis every 4 hours. Tickets cost $29–45 and the journey takes 3h 45m. Two other operators also service this route. Alternatively, Amtrak operates a train from Chicago Union Station to Indianapolis 3 times a week. Tickets cost $100–170 and the journey takes 4h 54m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Indianapolis
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $45–360
- Website
- united.com
Flights from Chicago O'Hare International Airport to Indianapolis
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $45–360
- Website
- southwest.com
Flights from Chicago Midway International Airport to Indianapolis
- Ave. Duration
- 59 min
- When
- Every day
- Estimated price
- $70–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $100–170
- Website
- Amtrak
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Clark/Lake to Midway
- Ave. Duration
- 27 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Indianapolis
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- $29–45
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Chicago Bus Station to Indianapolis
- Ave. Duration
- 3h 5m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Bus Station to Indianapolis
- Ave. Duration
- 3h 50m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Chicago Loop to Indianapolis bus services, operated by Flixbus USA, arrive at Indianapolis station.
Indianapolis is 1h ahead of Chicago Loop. It is currently 10:11 AM in Chicago Loop and 11:11 AM in Indianapolis.
Chicago Loop to Indianapolis train services, operated by Amtrak, arrive at Indianapolis station.
Yes, the driving distance between Chicago Loop to Indianapolis is 181 miles. It takes approximately 3h 13m to drive from Chicago Loop to Indianapolis.
Book your Chicago Loop to Indianapolis train tickets online with Omio.
Book your Chicago Loop to Indianapolis bus tickets online with Omio and FlixBus.
There are 740+ hotels available in Indianapolis.












