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How to get fromChicago, IL to Lexingtonby plane, car, bus (Greyhound), train, bus or bus (Flixbus, Greyhound)

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There are 8 ways to get from Chicago, IL to Lexington by plane, car, bus (Greyhound), train, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Louisville International Airport, drive

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    4h 59m
    $216–576

  2. Fly Chicago O'Hare International Airport to Blue Grass Airport, line 3 bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Take the bus from Transit Center to Centre Parkway @ 1349bus bus
    5h 49m
    $44–287

  3. Bus (Greyhound)

    1. Take the bus from Chicago Bus Station to Lexington Bus Stopbus bus Greyhound US0120
    9h 7m
    $79–152

  4. Train, bus

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus Greyhound US0120
    10h 5m
    $99–171

  5. Drive 362.2 mi

    1. Drive from Chicago, IL to Lexingtoncar car 362.2 mi
    6h 31m
    $67–96

  6. Fly Chicago Midway International Airport to Louisville International Airport, drive

    1. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    4h 43m
    $92–576

  7. Fly Chicago Midway International Airport to Blue Grass Airport

    1. Fly from Chicago Midway International Airport (MDW) to Blue Grass Airport (LEX)plane plane MDW - LEX
    8h 25m
    $74–427

  8. Bus via Indianapolis

    1. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus N2640 / ...
    2. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus Greyhound US0120
    9h 57m
    $91–159

Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF) flights

Calendar51Weekly Planes
Duration1h 35mAverage Duration
Ticket$57Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Lexington, KY, USA?

Greyhound USA operates a bus from Chicago Bus Station to Lexington Bus Stop once daily. Tickets cost $50–120 and the journey takes 8h 55m. Alternatively, Delta, Southwest Airlines, and American Airlines fly from Chicago Midway International Airport (MDW) to Blue Grass Airport (LEX) every 4 hours.

Airlines
Train operators
Bus operators

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