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How to get fromCheyenne to Lexingtonby plane, car, bus (Greyhound), bus, train or bus (Greyhound, Flixbus)

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There are 8 ways to get from Cheyenne to Lexington by plane, car, bus (Greyhound), bus, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cheyenne Airport to Louisville International Airport, drive

    best
    1. Fly from Cheyenne Airport (CYS) to Louisville International Airport (SDF)plane plane CYS - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 44m
    $146–660
  2. Fly Cheyenne Airport to Blue Grass Airport

    cheapest
    1. Fly from Cheyenne Airport (CYS) to Blue Grass Airport (LEX)plane plane CYS - LEX
    8h 59m
    $100–470
  3. Bus via St. Louis

    1. Take the bus from Cheyenne to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    31h 37m
    $192–389
  4. Bus, train

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Take the train from Denver to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    33h 52m
    $260–563
  5. Drive 1,218.3 mi

    1. Drive from Cheyenne to Lexingtoncar car 1,218.3 mi
    19h 50m
    $223–322
  6. Bus to Denver, fly to Louisville International Airport, drive

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to Louisville International Airport (SDF)plane plane DEN - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 14m
    $197–812
  7. Bus to Denver, fly to Blue Grass Airport

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to Blue Grass Airport (LEX)plane plane DEN - LEX
    8h 34m
    $155–643
  8. Bus

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    35h 48m
    $232–544

Cheyenne Airport (CYS) to Louisville International Airport (SDF) flights

Calendar19Weekly Planes
Duration6h 3mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

What companies run services between Cheyenne, WY, USA and Lexington, KY, USA?

You can take a bus from Cheyenne Regional Medical Center to Lexington via Cheyenne, Denver Union Station, St Louis Bus Station, Indianapolis Union Station, and Lexington Bus Stop in around 31h 37m. Alternatively, United Airlines flies from Cheyenne Airport (CYS) to Blue Grass Airport (LEX) twice daily.

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