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How to get fromCheyenne to Lexingtonby plane, car, bus (Greyhound), bus or train

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There are 8 ways to get from Cheyenne to Lexington by plane, car, bus (Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cheyenne Airport to Louisville International Airport, drive

    best
    1. Fly from Cheyenne Airport (CYS) to Louisville International Airport (SDF)planeCYS - SDF
    2. Drive from Louisville International Airport (SDF) to Lexingtoncar
    7h 2m
    $147–687
  2. Bus

    1. Take the bus from Cheyenne to Denver Union Stationbus
    2. Take the bus from Denver to Indianapolis Union Stationbus
    3. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
    31h 19m
    $247–512
  3. Bus, train

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus
    2. Take the train from Denver to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Indianapolistrain
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
    33h 52m
    $289–523
  4. Drive 1,218.3 mi

    1. Drive from Cheyenne to Lexingtoncar1,218.3 mi
    19h 35m
    $223–322
  5. Fly Cheyenne Airport to Blue Grass Airport

    1. Fly from Cheyenne Airport (CYS) to Blue Grass Airport (LEX)planeCYS - LEX
    8h 44m
    $215–1,018
  6. Bus to Denver, fly to Louisville International Airport, drive

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus
    2. Fly from Denver (DEN) to Louisville International Airport (SDF)planeDEN - SDF
    3. Drive from Louisville International Airport (SDF) to Lexingtoncar
    7h 14m
    $197–762
  7. Bus to Denver, fly to Blue Grass Airport

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus
    2. Fly from Denver (DEN) to Blue Grass Airport (LEX)planeDEN - LEX
    8h 36m
    $265–1,193
  8. Bus via Chicago

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus
    2. Take the bus from Denver Union Station to Chicago Bus Stationbus
    3. Take the bus from Chicago Bus Station to Lexington Bus Stopbus
    36h 29m
    $207–459

Cheyenne Airport (CYS) to Louisville International Airport (SDF) flights

Calendar21Weekly Planes
Duration6h 52mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

What companies run services between Cheyenne, WY, USA and Lexington, KY, USA?

You can take a bus from Cheyenne Regional Medical Center to Lexington via Cheyenne, Denver Union Station, Denver, Indianapolis Union Station, and Lexington Bus Stop in around 31h 19m. Alternatively, United Airlines flies from Cheyenne Airport (CYS) to Blue Grass Airport (LEX) 3 times a day.

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