There are 8 ways to get from Cheyenne to Lexington by plane, car, bus (Greyhound), bus, train, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Cheyenne Airport to Louisville International Airport, drive
best- Fly from Cheyenne Airport (CYS) to Louisville International Airport (SDF)plane CYS - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
6h 44m$146–660Fly Cheyenne Airport to Blue Grass Airport
cheapest- Fly from Cheyenne Airport (CYS) to Blue Grass Airport (LEX)plane CYS - LEX
8h 59m$100–470Bus via St. Louis
- Take the bus from Cheyenne to Denver Union Stationbus
- Take the bus from Denver Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
31h 37m$192–389Bus, train
- Take the bus from Warren AFB to Denver International Airport Pickupsbus
- Take the train from Denver to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
33h 52m$260–563Drive 1,218.3 mi
- Drive from Cheyenne to Lexingtoncar 1,218.3 mi
19h 50m$223–322Bus to Denver, fly to Louisville International Airport, drive
- Take the bus from Warren AFB to Denver International Airport Pickupsbus
- Fly from Denver (DEN) to Louisville International Airport (SDF)plane DEN - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
7h 14m$197–812Bus to Denver, fly to Blue Grass Airport
- Take the bus from Warren AFB to Denver International Airport Pickupsbus
- Fly from Denver (DEN) to Blue Grass Airport (LEX)plane DEN - LEX
8h 34m$155–643Bus
- Take the bus from Warren AFB to Denver International Airport Pickupsbus
- Take the bus from Denver Union Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Indianapolisbus
- Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
35h 48m$232–544
Cheyenne Airport (CYS) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Cheyenne to Lexington is to fly which costs $95 - $470 and takes 8h 59m.
The fastest way to get from Cheyenne to Lexington is to fly and drive which takes 6h 44m and costs $140 - $700.
The distance between Cheyenne and Lexington is 1119 miles. The road distance is 1225.4 miles.
The best way to get from Cheyenne to Lexington without a car is to bus via St. Louis which takes 31h 37m and costs $190 - $390.
It takes approximately 6h 44m to get from Cheyenne to Lexington, including transfers.
The best way to get from Cheyenne to Lexington is to bus via St. Louis which takes 31h 37m and costs $190 - $390. Alternatively, you can fly, which costs $95 - $470 and takes 8h 59m.
Lexington is 2h ahead of Cheyenne. It is currently 6:16 AM in Cheyenne and 8:16 AM in Lexington.
Yes, the driving distance between Cheyenne to Lexington is 1225 miles. It takes approximately 19h 50m to drive from Cheyenne to Lexington.
There are 119+ hotels available in Lexington.
What companies run services between Cheyenne, WY, USA and Lexington, KY, USA?
You can take a bus from Cheyenne Regional Medical Center to Lexington via Cheyenne, Denver Union Station, St Louis Bus Station, Indianapolis Union Station, and Lexington Bus Stop in around 31h 37m. Alternatively, United Airlines flies from Cheyenne Airport (CYS) to Blue Grass Airport (LEX) twice daily.
- Website
- united.com
Flights from Cheyenne Airport to Louisville International Airport via Denver
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $130–650
Flights from Cheyenne Airport to Blue Grass Airport via Denver
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $95–470
Flights from Cheyenne Airport to Blue Grass Airport via Denver, Chicago O'Hare
- Ave. Duration
- 8h 48m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–500
Flights from Denver to Louisville International Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- $130–700
Flights from Denver to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $150–750
Flights from Denver to Blue Grass Airport
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- $100–550
Flights from Denver to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $110–550
- Website
- southwest.com
Flights from Cheyenne Airport to Louisville International Airport via Denver
- Ave. Duration
- 5h 15m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Denver to Louisville International Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- $130–700
Flights from Denver to Louisville International Airport via Dallas
- Ave. Duration
- 5h 2m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–800
Flights from Denver to Louisville International Airport via Nashville
- Ave. Duration
- 4h 50m
- When
- Tuesday to Sunday
- Estimated price
- $150–750
- Website
- aa.com
Flights from Denver to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $170–800
Flights from Denver to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $130–650
Flights from Denver to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 9m
- When
- Monday, Tuesday, Thursday, and Sunday
- Estimated price
- $110–550
Flights from Denver to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 11m
- When
- Saturday
- Estimated price
- $120–600
- Website
- delta.com
Flights from Denver to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $130–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Denver to Chicago Union Station
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- $100–290
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Cheyenne to Denver Union Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $25–55
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to St Louis Bus Station
- Ave. Duration
- 16h 30m
- Frequency
- Once daily
- Estimated price
- $70–160
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a day
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- 4 times a week
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to Chicago Bus Station
- Ave. Duration
- 20h 35m
- Frequency
- Once daily
- Estimated price
- $80–280
- Website
- https://www.greyhound.com/
- Phone
- +1-877-779-2999
- tony@expressarrow.com
- Website
- expressarrow.com
Bus from Cheyenne to Denver Union Station
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a week
- Estimated price
- $45–60
- Website
- https://expressarrow.com
- Phone
- +1 970-226-5533
- Website
- groometransportation.com
Bus from Warren AFB to Denver International Airport Pickups
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $50–95
- Website
- https://groometransportation.com/denver-airport
- Schedules at
- https://groometransportation.com/wyoming
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Indianapolis
- Ave. Duration
- 3h 50m
- Frequency
- Every 4 hours
- Estimated price
- $35–70
- Schedules at
- flixbus.com
Want to know more about travelling around United States
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