There are 8 ways to get from Cheyenne to Lexington by plane, car, bus (Greyhound), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Cheyenne Airport to Louisville International Airport, drive
best- Fly from Cheyenne Airport (CYS) to Louisville International Airport (SDF)CYS - SDF
- Drive from Louisville International Airport (SDF) to Lexington
7h 2m$147–687Bus
- Take the bus from Cheyenne to Denver Union Station
- Take the bus from Denver to Indianapolis Union Station
- Take the bus from Indianapolis Union Station to Lexington Bus Stop
31h 19m$247–512Bus, train
- Take the bus from Warren AFB to Denver International Airport Pickups
- Take the train from Denver to Chicago Union Station
- Take the train from Chicago Union Station to Indianapolis
- Take the bus from Indianapolis Union Station to Lexington Bus Stop
33h 52m$289–523Drive 1,218.3 mi
- Drive from Cheyenne to Lexington1,218.3 mi
19h 35m$223–322Fly Cheyenne Airport to Blue Grass Airport
- Fly from Cheyenne Airport (CYS) to Blue Grass Airport (LEX)CYS - LEX
8h 44m$215–1,018Bus to Denver, fly to Louisville International Airport, drive
- Take the bus from Warren AFB to Denver International Airport Pickups
- Fly from Denver (DEN) to Louisville International Airport (SDF)DEN - SDF
- Drive from Louisville International Airport (SDF) to Lexington
7h 14m$197–762Bus to Denver, fly to Blue Grass Airport
- Take the bus from Warren AFB to Denver International Airport Pickups
- Fly from Denver (DEN) to Blue Grass Airport (LEX)DEN - LEX
8h 36m$265–1,193Bus via Chicago
- Take the bus from Warren AFB to Denver International Airport Pickups
- Take the bus from Denver Union Station to Chicago Bus Station
- Take the bus from Chicago Bus Station to Lexington Bus Stop
36h 29m$207–459
Cheyenne Airport (CYS) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Cheyenne to Lexington is to drive which costs $220 - $330 and takes 19h 35m.
The fastest way to get from Cheyenne to Lexington is to fly and drive which takes 7h 2m and costs $140 - $700.
The distance between Cheyenne and Lexington is 1121 miles. The road distance is 1225.4 miles.
The best way to get from Cheyenne to Lexington without a car is to bus which takes 31h 19m and costs $240 - $550.
It takes approximately 7h 2m to get from Cheyenne to Lexington, including transfers.
The best way to get from Cheyenne to Lexington is to bus which takes 31h 19m and costs $240 - $550. Alternatively, you can fly, which costs $210 - $1,100 and takes 8h 44m.
Lexington is 2h ahead of Cheyenne. It is currently 6:17 AM in Cheyenne and 8:17 AM in Lexington.
Yes, the driving distance between Cheyenne to Lexington is 1225 miles. It takes approximately 19h 35m to drive from Cheyenne to Lexington.
There are 136+ hotels available in Lexington.
What companies run services between Cheyenne, WY, USA and Lexington, KY, USA?
You can take a bus from Cheyenne Regional Medical Center to Lexington via Cheyenne, Denver Union Station, Denver, Indianapolis Union Station, and Lexington Bus Stop in around 31h 19m. Alternatively, United Airlines flies from Cheyenne Airport (CYS) to Blue Grass Airport (LEX) 3 times a day.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- united.com
Flights from Cheyenne Airport to Louisville International Airport via Denver
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $120–650
Flights from Cheyenne Airport to Blue Grass Airport via Denver
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Cheyenne Airport to Blue Grass Airport via Denver, Chicago O'Hare
- Ave. Duration
- 8h 27m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Denver to Louisville International Airport
- Ave. Duration
- 2h 38m
- When
- Every day
- Estimated price
- $130–650
Flights from Denver to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $140–700
Flights from Denver to Blue Grass Airport
- Ave. Duration
- 2h 52m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Denver to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $230–1,200
- Website
- southwest.com
Flights from Cheyenne Airport to Louisville International Airport via Denver
- Ave. Duration
- 7h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Denver to Louisville International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- $130–650
Flights from Denver to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- $140–700
Flights from Denver to Louisville International Airport via Dallas
- Ave. Duration
- 5h 2m
- When
- Monday and Saturday
- Estimated price
- $160–750
- Website
- aa.com
Flights from Denver to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $160–750
Flights from Denver to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $260–1,200
Flights from Denver to Blue Grass Airport via Charlotte
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $280–1,300
- Website
- delta.com
Flights from Denver to Louisville International Airport via Detroit
- Ave. Duration
- 5h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $160–800
Flights from Denver to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $270–1,300
Flights from Denver to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $260–1,200
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Denver to Chicago Union Station
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- $140–260
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–55
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Cheyenne to Denver Union Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $20–50
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $29–75
- Website
- https://www.greyhound.com/
Bus from Denver Union Station to Chicago Bus Station
- Ave. Duration
- 21h 15m
- Frequency
- Once daily
- Estimated price
- $80–250
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Lexington Bus Stop
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $50–90
- Website
- https://www.greyhound.com/
- Phone
- +1-877-779-2999
- tony@expressarrow.com
- Website
- expressarrow.com
Bus from Cheyenne to Denver Union Station
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a week
- Estimated price
- $45–55
- Website
- https://expressarrow.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Denver to Indianapolis Union Station
- Ave. Duration
- 21h 25m
- Frequency
- Once daily
- Estimated price
- $170–350
- Website
- https://burlingtontrailways.com
- Saver Fares
- $170–260
- Flexible Fares
- $240–350
- Saver Fare
- $203
- Flex Fare
- $279
- Phone
- +1 970-226-5533
- Website
- groometransportation.com
Bus from Warren AFB to Denver International Airport Pickups
- Ave. Duration
- 2h 20m
- Frequency
- Every 4 hours
- Estimated price
- $50–95
- Website
- https://groometransportation.com/denver-airport
- Schedules at
- https://groometransportation.com/wyoming
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