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How to get fromCheyenne to Iowaby plane, bus (Greyhound), car, or bus

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There are 6 ways to get from Cheyenne to Iowa by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cheyenne Airport to Des Moines

    best
    1. Fly from Cheyenne Airport (CYS) to Des Moines (DSM)plane plane CYS - DSM
    5h 42m
    $90–412

  2. Bus (Greyhound)

    1. Take the bus from Cheyenne to Denver Union Stationbus bus Greyhound US0560S
    2. Take the bus from Denver Union Station to Des Moinesbus bus Greyhound US0123S
    17h 45m
    $145–226

  3. Drive  628.4 mi

    1. Drive from Cheyenne to Des Moinescar car 628.4 mi
    9h 39m
    $104–150

  4. Fly Cheyenne Airport to Omaha

    1. Fly from Cheyenne Airport (CYS) to Omaha (OMA)plane plane CYS - OMA
    5h 57m
    $94–516

  5. Bus to Denver, fly to Des Moines

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to Des Moines (DSM)plane plane DEN - DSM
    5h 11m
    $131–474

  6. Bus via Omaha

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Take the bus from Denver to Omahabus bus
    3. Take the bus from Omaha, NE to Des Moinesbus bus
    17h 47m
    $235–321

Cheyenne Airport (CYS) to Des Moines (DSM) flights

Calendar28Weekly Planes
Duration7h 19mAverage Duration
Ticket$71Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cheyenne to Iowa.ExpandLaunch map view
  • Distance: 586.3 mi
  • Duration: 5h 42m

What companies run services between Cheyenne, WY, USA and Iowa, USA?

United Airlines flies from Cheyenne Airport (CYS) to Des Moines (DSM) 4 times a day. Alternatively, you can take a bus from Cheyenne Regional Medical Center to Des Moines via Cheyenne, Denver Union Station, and Des Moines in around 17h 45m.

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Want to know more about travelling around United States

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Need to know: Greyhound

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