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How to get fromCharlotte to Iowaby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

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There are 10 ways to get from Charlotte to Iowa by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    4h 3m
    $199–973

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Charlotte Douglas International Airport (CLT) to Quad City International Airport (MLI)plane plane CLT - MLI
    5h 19m
    $94–484

  3. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    26h 40m
    $177–358

  4. Train, bus

    1. Take the train from Charlotte Amtrak Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    32h 46m
    $347–699

  5. Drive 1,030 mi

    1. Drive from Charlotte to Des Moinescar car 1,030 mi
    17h 42m
    $188–272

  6. Fly to Omaha

    1. Fly from Charlotte Douglas International Airport (CLT) to Omaha (OMA)plane plane CLT - OMA
    4h 15m
    $197–882

  7. Fly to The Eastern Iowa Airport, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to The Eastern Iowa Airport (CID)plane plane CLT - CID
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    6h 46m

  8. Bus via Columbus

    1. Take the bus from Charlotte Bus Station to Hurricanebus bus
    2. Take the bus from Hurricane to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Mound St to Chicagobus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    27h 45m
    $134–315

  9. Train, bus via Chicago

    1. Take the train from Charlotte Amtrak Station to Carytrain train
    2. Take the train from Cary to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    36h 57m
    $450–911

  10. Train, bus via Galesburg

    1. Take the train from Charlotte Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    38h 20m
    $483–991

Charlotte Douglas International Airport (CLT) to Des Moines (DSM) flights

Calendar94Weekly Planes
Duration4h 36mAverage Duration
Ticket$183Cheapest Price
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Questions & Answers

Map of how to get from Charlotte to Iowa.ExpandLaunch map view
  • Distance: 827.6 mi
  • Duration: 4h 3m

What companies run services between Charlotte, NC, USA and Iowa, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Charlotte Bus Station to Des Moines via Atlanta Bus Station, St Louis Bus Station, and Des Moines in around 26h 40m.

Airlines
Train operators
Bus operators

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