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How to get fromCharlotte to Iowaby plane, bus (Flixbus), train, bus or car

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There are 9 ways to get from Charlotte to Iowa by plane, bus (Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)planeCLT - DSM
    4h 9m
    $149–773

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Charlotte Douglas International Airport (CLT) to Quad City International Airport (MLI)planeCLT - MLI
    5h 21m
    $69–364

  3. Bus

    1. Take the bus from Charlotte to Atlanta Bus Stationbus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
    3. Take the bus from St Louis to Burlingtonbus
    4. Take the bus from Burlington to Des Moinesbus
    25h 45m
    $187–426

  4. Train, bus

    1. Take the train from Charlotte Amtrak Station to Raleigh Union Stationtrain
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
    4. Take the bus from Galesburg to Burlingtonbus
    5. Take the bus from Burlington to Des Moinesbus
    38h 44m
    $296–1,198

  5. Drive 1,030.9 mi

    1. Drive from Charlotte to Des Moinescar1,030.9 mi
    17h 25m
    $189–272

  6. Fly to Omaha

    1. Fly from Charlotte Douglas International Airport (CLT) to Omaha (OMA)planeCLT - OMA
    4h 29m
    $157–732

  7. Fly to The Eastern Iowa Airport

    1. Fly from Charlotte Douglas International Airport (CLT) to The Eastern Iowa Airport (CID)planeCLT - CID
    5h 27m
    $88–412

  8. Bus, train

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus
    2. Take the train from Toledo to Chicago Union Stationtrain
    3. Take the bus from Chicago to Des Moinesbus
    27h 7m
    $197–606

  9. Bus via Columbus

    1. Take the bus from Charlotte Bus Station to Hurricanebus
    2. Take the bus from Hurricane to Columbus - Mound Stbus
    3. Take the bus from Columbus - Mound St to Chicagobus
    4. Take the bus from Chicago to Des Moinesbus
    28h 20m
    $131–369

Charlotte to Iowa by bus

Calendar5Weekly Buses
Duration25h 45mAverage Duration
Ticket$187Cheapest Price
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Questions & Answers

What companies run services between Charlotte, NC, USA and Iowa, USA?

American Airlines, Delta, and United Airlines fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Charlotte to Des Moines via Atlanta Bus Station, St Louis, and Burlington in around 25h 45m.

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