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How to get fromCharlotte to Iowaby plane, bus, train, car, bus (Flixbus, Greyhound) or bus (Greyhound)

Find Transport to Iowa

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There are 8 ways to get from Charlotte to Iowa by plane, bus, train, car, bus (Flixbus, Greyhound), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    4h 12m
    $89–403

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Charlotte Douglas International Airport (CLT) to Quad City International Airport (MLI)plane plane CLT - MLI
    5h 26m
    $64–354

  3. Bus, train

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    26h 36m
    $195–424

  4. Drive 1,030.9 mi

    1. Drive from Charlotte to Des Moinescar car 1,030.9 mi
    17h 38m
    $189–272

  5. Fly to Omaha

    1. Fly from Charlotte Douglas International Airport (CLT) to Omaha (OMA)plane plane CLT - OMA
    4h 28m
    $217–1,032

  6. Fly to The Eastern Iowa Airport, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to The Eastern Iowa Airport (CID)plane plane CLT - CID
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    6h 52m

  7. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    27h 14m
    $162–318

  8. Bus via Columbus

    1. Take the bus from Charlotte Bus Station to Hurricanebus bus
    2. Take the bus from Hurricane to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Mound St to Chicagobus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    27h 49m
    $124–300

Charlotte Douglas International Airport (CLT) to Des Moines (DSM) flights

Calendar74Weekly Planes
Duration4h 34mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

What companies run services between Charlotte, NC, USA and Iowa, USA?

American Airlines, Delta, and two other airlines fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Charlotte Bus Station to Des Moines via Atlanta Bus Station, Chicago Bus Station, and Des Moines in around 27h 14m.

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