Rome2Rio

How to get fromCharlotte to Iowaby plane, bus (Flixbus, Greyhound), train, bus, car or bus (Greyhound)

Find Transport to Iowa

See all options

There are 10 ways to get from Charlotte to Iowa by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    4h 8m
    $169–873

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Charlotte Douglas International Airport (CLT) to Quad City International Airport (MLI)plane plane CLT - MLI
    5h 24m
    $69–384

  3. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    25h 16m
    $175–385

  4. Train, bus

    1. Take the train from Charlotte Amtrak Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    32h 46m
    $314–676

  5. Drive 1,030.9 mi

    1. Drive from Charlotte to Des Moinescar car 1,030.9 mi
    17h 39m
    $189–272

  6. Fly to Omaha

    1. Fly from Charlotte Douglas International Airport (CLT) to Omaha (OMA)plane plane CLT - OMA
    4h 25m
    $187–882

  7. Fly to The Eastern Iowa Airport, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to The Eastern Iowa Airport (CID)plane plane CLT - CID
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    6h 46m

  8. Bus via Columbus

    1. Take the bus from Charlotte Bus Station to Hurricanebus bus
    2. Take the bus from Hurricane to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Mound St to Chicagobus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    27h 45m
    $134–330

  9. Train, bus via Chicago

    1. Take the train from Charlotte Amtrak Station to Carytrain train
    2. Take the train from Cary to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    37h 6m
    $393–868

  10. Train, bus via Chicago #2

    1. Take the train from Charlotte Amtrak Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bloomington-Normaltrain train
    4. Take the bus from Bloomington-Normal to Des Moinesbus bus
    39h 31m
    $420–927

Charlotte Douglas International Airport (CLT) to Des Moines (DSM) flights

Calendar100Weekly Planes
Duration4h 39mAverage Duration
Ticket$156Cheapest Price
See schedules

Questions & Answers

What companies run services between Charlotte, NC, USA and Iowa, USA?

American Airlines, Delta, and United Airlines fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Charlotte Bus Station to Des Moines via Atlanta Bus Station, St Louis Bus Station, and Des Moines in around 25h 16m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Charlotte

Trips to Iowa

Popular routes