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How to get fromCharlotte to Florida Keysby plane, bus, shuttle, train, car or bus (Flixbus, Greyhound)

Find Transport to Florida Keys

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There are 9 ways to get from Charlotte to Florida Keys by plane, bus, shuttle, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charlotte Douglas International Airport to Key West International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)plane plane CLT - EYW
    6h 35m
    $159–571

  2. Bus

    cheapest
    1. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    21h 55m
    $114–245

  3. Bus, shuttle

    1. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Fort Lauderdale International Airportbus bus
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    21h 37m
    $241–410

  4. Bus, train

    1. Take the bus from Charlotte Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    28h 15m
    $181–369

  5. Drive 867.4 mi

    1. Drive from Charlotte to Florida Keyscar car 867.4 mi
    15h 1m
    $159–229

  6. Fly Charlotte Douglas International Airport to Miami International Airport, shuttle

    1. Fly from Charlotte Douglas International Airport (CLT) to Miami International Airport (MIA)plane plane CLT - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 7m
    $179–456

  7. Fly Concord to Key West International Airport

    1. Fly from Concord (USA) to Key West International Airport (EYW)plane plane USA - EYW
    9h 41m
    $154–521

  8. Fly Charlotte Douglas International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Charlotte Douglas International Airport (CLT) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CLT - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 30m
    $204–436

  9. Train, bus

    1. Take the train from Charlotte Amtrak Station to Carytrain train
    2. Take the train from Cary to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    32h 12m
    $154–320

Charlotte to Florida Keys by bus, foot, and shuttle

Calendar14Weekly Services
Duration21h 37mAverage Duration
Ticket$241Cheapest Price
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Questions & Answers

What companies run services between Charlotte, NC, USA and Florida Keys, FL, USA?

American Airlines and Delta fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Charlotte Bus Station to Florida Keys via Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 21h 55m.

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