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How to get fromCharlotte to Buffaloby plane, bus (Greyhound), train (Amtrak), car, bus or bus (Flixbus)

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There are 6 ways to get from Charlotte to Buffalo by plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane plane CLT - BUF
    4h 25m
    $146–982

  2. Bus

    cheapest
    1. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus
    2. Take the bus from Charleston, WV to Robert K Pfaff Transit Center - Akronbus bus
    3. Take the bus from Robert K Pfaff Transit Center - Akron to Buffalo, NYbus bus
    16h 40m
    $73–217

  3. Train (Amtrak)

    1. Take the train from Charlotte Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    22h 56m
    $174–370

  4. Drive 653.8 mi

    1. Drive from Charlotte to Buffalocar car 653.8 mi
    11h 10m
    $120–173

  5. Fly to Rochester, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Rochester (ROC)plane plane CLT - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus bus
    6h 30m
    $166–687

  6. Bus via New York (Flixbus)

    1. Take the bus from Charlotte Bus Station to New York Midtownbus bus FlixBus N2471 / ...
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    22h 11m
    $122–219

Charlotte to Buffalo by bus

Calendar7Weekly Buses
Duration16h 40mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

What companies run services between Charlotte, NC, USA and Buffalo, NY, USA?

American Airlines, United Airlines, and two other airlines fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, you can take a bus from Charlotte Bus Station to Buffalo, NY via Charleston, WV and Robert K Pfaff Transit Center - Akron in around 16h 40m.

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Need to know: Greyhound

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