There are 5 ways to get from Charleston to Greenville by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3 h 28 min

  1. CRW - GSP

$213 - $961

Cheapest option

Bus  •  11 h 35 min

$65 - $140

3 alternative options

Bus, train  •  11 h 58 min

$77 - $186

Train  •  15 h 51 min

  1. Cardinal
  2. Crescent

$110 - $284

Drive  •  6 h 4 min

  1. 361.3 miles

$35 - $55

What companies run services between Charleston, WV, USA and Greenville, SC, USA?

American Airlines, Delta and United Airlines fly from Charleston to Greenville hourly. Alternatively, you can take a bus from Charleston to Greenville via Winston Salem, Nc, Asheville, Nc, and Asheville in around 11 h 35 min.

Airlines
American Airlines
Website
aa.com
Flights from Charleston to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 19 min
When
Every day
Estimated price
$170 - $900
Flights from Charleston to Greenville/Spartanburg via Reagan Washington
Ave. Duration
4 h 13 min
When
Monday to Friday
Estimated price
$190 - $950
Flights from Charleston to Greenville/Spartanburg via Philadelphia
Ave. Duration
4 h 18 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,000
Flights from Charleston to Greenville/Spartanburg via Reagan Washington, Charlotte
Ave. Duration
6 h 21 min
When
Monday to Saturday
Estimated price
$200 - $950
Delta
Website
delta.com
Flights from Charleston to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h 18 min
When
Every day
Estimated price
$170 - $900
United Airlines
Website
united.com
Flights from Charleston to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$210 - $1,000
Flights from Charleston to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
5 h 50 min
When
Every day
Estimated price
$230 - $1,100
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Greensboro Galyon Transportation Center Amtrak to Greenville Amtrak
Ave. Duration
4 h 32 min
Frequency
Twice daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $65
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Train from Charleston Amtrak to Charlottesville Amtrak
Ave. Duration
6 h 49 min
Frequency
5 times a week
Estimated price
$45 - $130
Website
amtrak.com
Coach Seat
$45 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Train from Charlottesville Amtrak to Greenville Amtrak
Ave. Duration
8 h 2 min
Frequency
Twice daily
Estimated price
$60 - $160
Website
amtrak.com
Coach Seat
$60 - $90
Flexi Coach Seat
$100 - $160
Business Coach Seat
$110 - $160
Room
$270 - $380
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Charleston, Wv to Winston Salem, Nc
Ave. Duration
5 h 15 min
Frequency
Hourly
Estimated price
$27 - $70
Website
greyhound.com
Economy
$27 - $45
Flexible
$50 - $70
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Winston Salem, Nc to Greensboro, Nc
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$9 - $21
Website
greyhound.com
Economy
$9 - $14
Flexible
$16 - $21

Want to know more about travelling around United States

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Questions & Answers

The distance between Charleston and Greenville is 395 km. The road distance is 578 km.

The cheapest way to get from Charleston to Greenville is to drive which costs $35 - $55 and takes 6 h 4 min.

The quickest way to get from Charleston to Greenville is to fly which takes 3 h 28 min and costs $210 - $1,000.

No, there is no direct train from Charleston to Greenville. However, there are services departing from Charleston Amtrak and arriving at Greenville Amtrak via Charlottesville Amtrak. The journey, including transfers, takes approximately 15 h 51 min.

No, there is no direct bus from Charleston to Greenville. However, there are services departing from Charleston, Wv and arriving at Greenville via Winston Salem, Nc and Asheville. The journey, including transfers, takes approximately 11 h 35 min.

It takes approximately 3 h 28 min to get from Charleston to Greenville, including transfers.