There are 7 ways to get from Charleston to Panama City by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Panama City  •  6 h 2 min

  1. Fly from Charleston (CHS) to Panama City (ECP) CHS - ECP

$275 - $1,100

Cheapest option

Bus  •  10 h 48 min

  1. Take the bus from Charleston, SC to Savannah, GA
  2. Take the bus from Savannah, Ga to Jacksonville, Fl
  3. Take the bus from Jacksonville, Fl to Tallahassee, Fl
  4. Take the bus from Tallahassee, Fl to Panama City, Fl

$79 - $173

5 alternative options

Fly to Tallahassee, bus  •  6 h 25 min

  1. Fly from Charleston (CHS) to Tallahassee (TLH) CHS - TLH
  2. Take the bus from Tallahassee, Fl to Panama City, Fl

$251 - $1,055

Fly to Valparaiso, drive  •  6 h 21 min

  1. Fly from Charleston (CHS) to Valparaiso (VPS) CHS - VPS
  2. Drive from Valparaiso to Panama City

$201 - $935

Fly to Pensacola, bus  •  8 h 6 min

  1. Fly from Charleston (CHS) to Pensacola (PNS) CHS - PNS
  2. Take the bus from Pensacola, Fl to Panama City, Fl

$218 - $935

Fly to Dothan, drive  •  6 h 33 min

  1. Fly from Charleston (CHS) to Dothan (DHN) CHS - DHN
  2. Drive from Dothan to Panama City

$243 - $1,238

Drive  •  8 h 44 min

  1. Drive from Charleston to Panama City 503.2 miles

$45 - $75

What companies run services between Charleston, SC, USA and Panama City, FL, USA?

Delta, American Airlines and two other airlines fly from Charleston to Panama City hourly. Alternatively, you can take a bus from Charleston to Panama City via N. Charleston SuperStop on Rivers Ave, Charleston, SC, Savannah, GA, Savannah, Ga, Jacksonville, Fl, and Tallahassee, Fl in around 10 h 48 min.

Airlines
Delta
Website
delta.com
Flights from Charleston to Panama City via Atlanta
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$190 - $1,000
Flights from Charleston to Tallahassee via Atlanta
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$180 - $950
Flights from Charleston to Valparaiso via Atlanta
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$170 - $900
Flights from Charleston to Pensacola via Atlanta
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$160 - $850
Flights from Charleston to Dothan via Atlanta
Ave. Duration
3 h 29 min
When
Every day
Estimated price
$210 - $1,200
American Airlines
Website
aa.com
Flights from Charleston to Panama City via Charlotte
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$210 - $1,100
Flights from Charleston to Panama City via Dallas/Ft.Worth
Ave. Duration
7 h 26 min
When
Every day
Estimated price
$310 - $1,300
Flights from Charleston to Tallahassee via Charlotte
Ave. Duration
5 h 8 min
When
Every day
Estimated price
$200 - $1,000
Flights from Charleston to Tallahassee via Miami
Ave. Duration
5 h 43 min
When
Every day
Estimated price
$230 - $1,100
Flights from Charleston to Tallahassee via Reagan Washington
Ave. Duration
4 h 59 min
When
Friday
Estimated price
$250 - $1,100
Flights from Charleston to Tallahassee via Dallas/Ft.Worth
Ave. Duration
6 h 59 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $1,200
Flights from Charleston to Valparaiso via Charlotte
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$190 - $950
Flights from Charleston to Valparaiso via Dallas/Ft.Worth
Ave. Duration
5 h 49 min
When
Every day
Estimated price
$270 - $1,100
Flights from Charleston to Pensacola via Charlotte
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$180 - $900
Flights from Charleston to Pensacola via Miami
Ave. Duration
5 h 15 min
When
Every day
Estimated price
$210 - $950
Flights from Charleston to Pensacola via Reagan Washington
Ave. Duration
5 h 38 min
When
Every day
Estimated price
$230 - $1,000
Flights from Charleston to Pensacola via Philadelphia
Ave. Duration
6 h 13 min
When
Saturday
Estimated price
$250 - $1,000
Southwest Airlines
Website
southwest.com
Flights from Charleston to Panama City via Nashville
Ave. Duration
6 h 35 min
When
Friday, Saturday and Sunday
Estimated price
$250 - $1,100
Flights from Charleston to Panama City via Baltimore
Ave. Duration
6 h 42 min
When
Saturday and Sunday
Estimated price
$300 - $1,200
Flights from Charleston to Panama City via Houston Hobby Apt
Ave. Duration
6 h 40 min
When
Sunday
Estimated price
$330 - $1,300
Flights from Charleston to Panama City via Chicago Midway
Ave. Duration
8 h 40 min
When
Saturday
Estimated price
$330 - $1,300
Flights from Charleston to Pensacola via Nashville
Ave. Duration
6 h 15 min
When
Friday and Saturday
Estimated price
$210 - $900
United Airlines
Website
united.com
Flights from Charleston to Panama City via Houston
Ave. Duration
7 h 4 min
When
Every day
Estimated price
$300 - $1,300
Flights from Charleston to Valparaiso via Houston
Ave. Duration
6 h 25 min
When
Every day
Estimated price
$260 - $1,200
Flights from Charleston to Pensacola via Houston
Ave. Duration
5 h 50 min
When
Every day
Estimated price
$250 - $1,100
Flights from Charleston to Pensacola via Chicago O'Hare
Ave. Duration
6 h 7 min
When
Every day
Estimated price
$260 - $1,100
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tallahassee, Fl to Panama City, Fl
Ave. Duration
1 h 15 min
Frequency
Every 15 minutes
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Pensacola, Fl to Panama City, Fl
Ave. Duration
2 h 40 min
Frequency
Every 30 minutes
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40
Bus from Savannah, Ga to Jacksonville, Fl
Ave. Duration
2 h 15 min
Frequency
Every 15 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45
Bus from Jacksonville, Fl to Tallahassee, Fl
Ave. Duration
2 h 40 min
Frequency
Hourly
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50

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Questions & Answers

How far is it from Charleston to Panama City?

The distance between Charleston and Panama City is 616 km. The road distance is 805 km.

What is the cheapest way to get from Charleston to Panama City?

The cheapest way to get from Charleston to Panama City is to drive which costs $45 - $75 and takes 8 h 44 min.

What is the fastest way to get from Charleston to Panama City?

The quickest way to get from Charleston to Panama City is to fly which takes 6 h 2 min and costs $270 - $1,100.

Is there a direct bus between Charleston and Panama City?

No, there is no direct bus from Charleston to Panama City. However, there are services departing from Mary St / Meeting St and arriving at Panama City, Fl via Charleston, SC, Savannah, Ga, Jacksonville, Fl and Tallahassee, Fl. The journey, including transfers, takes approximately 10 h 48 min.

How long does it take to get from Charleston to Panama City?

It takes approximately 6 h 2 min to get from Charleston to Panama City, including transfers.