There are 5 ways to get from Charleston to Jacksonville by car, train, bus or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Drive, train  •  5 h 44 min

  1. Drive from Charleston to Yemassee Amtrak
  2. Take the train from Yemassee Amtrak to Jacksonville Amtrak Silver Meteor

$48 - $111

Cheapest option

Bus  •  6 h 14 min

  1. Take the bus from Charleston, SC to Savannah, GA 0972 / ...
  2. Take the bus from Savannah, Ga to Jacksonville, Fl 1019 / ...

$42 - $83

3 alternative options

Drive  •  4 h 13 min

  1. Drive from Charleston to Jacksonville 240.3 miles

$23 - $35

Fly to Jacksonville  •  6 h 3 min

  1. Fly from Charleston (CHS) to Jacksonville (JAX) CHS - JAX

$157 - $727

Fly to Brunswick, bus  •  6 h 18 min

  1. Fly from Charleston (CHS) to Brunswick (BQK) CHS - BQK
  2. Take the bus from Brunswick to Jacksonville, Fl

$261 - $1,183

Questions & Answers

The cheapest way to get from Charleston to Jacksonville is to drive which costs $23 - $35 and takes 4 h 13 min.

More details

The quickest way to get from Charleston to Jacksonville is to drive which takes 4 h 13 min and costs $23 - $35.

More details

The distance between Charleston and Jacksonville is 317 km. The road distance is 385 km.

Get driving directions

It takes approximately 5 h 44 min to get from Charleston to Jacksonville, including transfers.

More details

No, there is no direct bus from Charleston to Jacksonville. However, there are services departing from Mary St / Meeting St and arriving at Jacksonville, Fl via Charleston, SC and Savannah, Ga. The journey, including transfers, takes approximately 6 h 14 min.

More details

What companies run services between Charleston, SC, USA and Jacksonville, FL, USA?

You can take a bus from Charleston to Jacksonville via N. Charleston SuperStop on Rivers Ave, Charleston, SC, Savannah, GA, and Savannah, Ga in around 6 h 14 min. Alternatively, Delta, American Airlines and two other airlines fly from Charleston to Jacksonville hourly.

Airlines
Delta
Website
delta.com
Flights from Charleston to Jacksonville via Atlanta
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$130 - $700
Flights from Charleston to Brunswick via Atlanta
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$200 - $1,100
American Airlines
Website
aa.com
Flights from Charleston to Jacksonville via Charlotte
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$140 - $700
Flights from Charleston to Jacksonville via Miami
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$160 - $750
Flights from Charleston to Jacksonville via Reagan Washington
Ave. Duration
4 h 40 min
When
Saturday
Estimated price
$180 - $800
Southwest Airlines
Website
southwest.com
Flights from Charleston to Jacksonville via Nashville
Ave. Duration
4 h 5 min
When
Saturday
Estimated price
$180 - $750
Flights from Charleston to Jacksonville via Baltimore
Ave. Duration
4 h 47 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $800
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Yemassee Amtrak to Jacksonville Amtrak
Ave. Duration
3 h 26 min
Frequency
Twice daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Bus operators
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Savannah, Ga to Jacksonville, Fl
Ave. Duration
2 h 15 min
Frequency
Every 15 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45
Bus from Brunswick to Jacksonville, Fl
Ave. Duration
1 h 5 min
Frequency
Every 20 minutes
Estimated price
$13 - $30
Website
greyhound.com
Economy
$13 - $20
Flexible
$23 - $30

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