There are 5 ways to get from Charleston to Great Smoky Mountains National Park by bus, car, taxi or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, drive via Columbia, SC  •  10 h 4 min

  1. Take the bus from Charleston, SC to Columbia, SC
  2. Take the bus from Columbia to Asheville
  3. Drive from Asheville to Great Smoky Mountains National Park

$81 - $113

Cheapest option

Bus, drive  •  13 h 28 min

  1. Take the bus from Charleston, SC to Columbia
  2. Take the bus from Columbia to Asheville
  3. Drive from Asheville to Great Smoky Mountains National Park

$65 - $109

3 alternative options

Bus, Megabus, taxi  •  15 h 55 min

  1. Take the bus from Charleston, SC to Savannah, GA
  2. Take the bus from Savannah, Ga to Atlanta Arpt, Ga
  3. Take the Megabus from Atlanta GA to Knoxville
  4. Take a taxi from Mountain Grove SB before Majestic Grove to Great Smoky Mountains National Park

$288 - $408

Drive  •  5 h 28 min

  1. Drive from Charleston to Great Smoky Mountains National Park 332.9 miles

$30 - $50

Fly, drive  •  6 h 10 min

  1. Fly from Charleston (CHS) to Knoxville (TYS) CHS - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$180 - $884

What companies run services between Charleston, SC, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Charleston to Great Smoky Mountains National Park. However, you can take the line 10 bus to N. Charleston SuperStop on Rivers Ave, take the walk to Charleston, SC, take the bus to Columbia, SC, take the taxi to Columbia, take the bus to Asheville, then take the drive to Great Smoky Mountains National Park. Alternatively, you can take the line 10 bus to N. Charleston SuperStop on Rivers Ave, take the walk to Charleston, SC, take the bus to Columbia, take the bus to Asheville, then take the drive to Great Smoky Mountains National Park.

Airlines
Delta
Website
delta.com
Flights from Charleston to Knoxville via Atlanta
Ave. Duration
3 h 13 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$150 - $850
Flights from Charleston to Knoxville via Detroit
Ave. Duration
5 h 37 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $950
Flights from Charleston to Knoxville via New York La Guardia
Ave. Duration
5 h 19 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,000
American Airlines
Website
aa.com
Flights from Charleston to Knoxville via Charlotte
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$160 - $850
Flights from Charleston to Knoxville via Chicago O'Hare
Ave. Duration
5 h 20 min
When
Every day
Estimated price
$230 - $950
Flights from Charleston to Knoxville via Reagan Washington
Ave. Duration
6 h 51 min
When
Monday to Saturday
Estimated price
$200 - $900
United Airlines
Website
united.com
Flights from Charleston to Knoxville via Washington Dulles
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$210 - $950
Flights from Charleston to Knoxville via Chicago O'Hare
Ave. Duration
5 h 6 min
When
Every day
Estimated price
$230 - $1,100
Flights from Charleston to Knoxville via Houston
Ave. Duration
6 h 40 min
When
Monday to Friday
Estimated price
$260 - $1,200
Bus operators
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Charleston, SC to Columbia, SC
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$24 - $35
Schedules at
southeasternstages.com
Bus from Columbia to Asheville
Ave. Duration
3 h 15 min
Frequency
Once daily
Estimated price
$29 - $40
Schedules at
southeasternstages.com
Bus from Charleston, SC to Columbia
Ave. Duration
5 h 58 min
Frequency
Once daily
Estimated price
$27 - $55
Schedules at
southeasternstages.com
Bus from Charleston, SC to Savannah, GA
Ave. Duration
2 h 18 min
Frequency
Twice daily
Estimated price
$21 - $35
Schedules at
southeasternstages.com
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Savannah, Ga to Atlanta Arpt, Ga
Ave. Duration
4 h 10 min
Frequency
Every 30 minutes
Estimated price
$28 - $70
Website
greyhound.com
Economy
$28 - $45
Flexible
$50 - $70
Other operators
Taxi from Mountain Grove SB before Majestic Grove to Great Smoky Mountains National Park
Ave. Duration
1 h 26 min
Estimated price
$210 - $260
Knoxville Taxi Service
Phone
+1 865 691 1900
Website
knoxvilletaxicab.com

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Questions & Answers

The distance between Charleston and Great Smoky Mountains National Park is 455 km. The road distance is 533 km.

The cheapest way to get from Charleston to Great Smoky Mountains National Park is to drive which costs $30 - $50 and takes 5 h 28 min.

The quickest way to get from Charleston to Great Smoky Mountains National Park is to drive which takes 5 h 28 min and costs $30 - $50.

It takes approximately 10 h 4 min to get from Charleston to Great Smoky Mountains National Park, including transfers.

Trips to Great Smoky Mountains National Park

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