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There are 3 ways to get from Charleston to Great Smoky Mountains National Park by bus, plane or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, travel  •  14h 25m

  1. Take the bus from Charleston to Columbia, SC
  2. Take the bus from Columbia, Sc to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Travel from Asheville, Nc to Great Smoky Mountains National Park

2 alternative options

Fly from Charleston, travel  •  5h 44m

  1. Fly from Charleston (CHS) to Knoxville (TYS) CHS - TYS
  2. Travel from Knoxville to Great Smoky Mountains National Park

Drive to Hilton Head, fly, travel  •  7h 8m

  1. Drive from Charleston to Hilton Head
  2. Fly from Hilton Head (HHH) to Knoxville (TYS) HHH - TYS
  3. Travel from Knoxville to Great Smoky Mountains National Park

Questions & Answers

The distance between Charleston and Great Smoky Mountains National Park is 284 miles.

The best way to get from Charleston to Great Smoky Mountains National Park without a car is to bus and travel which takes 14h 25m and costs .

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It takes approximately 14h 25m to get from Charleston to Great Smoky Mountains National Park, including transfers.

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There is no direct flight from Charleston Airport to Knoxville Airport. The quickest flight takes 3h 15m and has one stopover.

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United Airlines, American Airlines and Delta offer flights from Charleston Airport to Knoxville Airport.

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There are 1723+ hotels available in Great Smoky Mountains National Park. Prices start at $119 USD per night.

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The best way to get from Charleston to Charleston Airport is to Shuttle Bus which takes 30m and costs $25.

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Map of how to get from Charleston to Great Smoky Mountains National Park.
Launch map view
  • Distance: 284.3 miles
  • Duration: 14h 25m

What companies run services between Charleston, SC, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Charleston to Great Smoky Mountains National Park. However, you can take the bus to Columbia, SC, take the walk to Columbia, Sc, take the bus to Winston Salem, Nc, take the bus to Asheville, Nc, then take the travel to Great Smoky Mountains National Park. Alternatively, you can take the Shuttle Bus to Charleston Airport, take the walk to Charleston airport, fly to Knoxville, then take the travel to Great Smoky Mountains National Park.

Airlines
American Airlines
Website
aa.com
Flights from Charleston to Knoxville via Charlotte
Ave. Duration
3h 33m
When
Every day
Estimated price
$160 - $850
Flights from Charleston to Knoxville via Reagan Washington
Ave. Duration
4h 28m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $900
Flights from Charleston to Knoxville via Miami
Ave. Duration
5h 1m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $950
Flights from Charleston to Knoxville via Philadelphia
Ave. Duration
5h 31m
When
Every day
Estimated price
$220 - $950
Flights from Hilton Head to Knoxville via Charlotte
Ave. Duration
4h 33m
When
Every day
Estimated price
$110 - $600
Flights from Hilton Head to Knoxville via Charlotte, Reagan Washington
Ave. Duration
6h 48m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $650
Flights from Hilton Head to Knoxville via Charlotte, Philadelphia
Ave. Duration
7h 25m
When
Monday to Saturday
Estimated price
$160 - $700
Flights from Hilton Head to Knoxville via Charlotte, Chicago O'Hare
Ave. Duration
7h 33m
When
Every day
Estimated price
$160 - $700
Delta
Website
delta.com
Flights from Charleston to Knoxville via Atlanta
Ave. Duration
4h 12m
When
Every day
Estimated price
$150 - $850
Flights from Charleston to Knoxville via Detroit
Ave. Duration
5h 13m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $950
Flights from Charleston to Knoxville via New York La Guardia
Ave. Duration
5h 23m
When
Monday to Friday
Estimated price
$210 - $1,000
United Airlines
Website
united.com
Flights from Charleston to Knoxville via Washington Dulles
Ave. Duration
4h 6m
When
Every day
Estimated price
$210 - $950
Flights from Charleston to Knoxville via Houston
Ave. Duration
6h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,200
Flights from Charleston to Knoxville via Chicago O'Hare
Ave. Duration
6h 31m
When
Every day
Estimated price
$230 - $1,100
Flights from Hilton Head to Knoxville via Washington Dulles
Ave. Duration
4h 50m
When
Every day
Estimated price
$150 - $700
Flights from Hilton Head to Knoxville via Newark
Ave. Duration
7h 11m
When
Saturday and Sunday
Estimated price
$170 - $750
Flights from Hilton Head to Knoxville via Chicago O'Hare
Ave. Duration
7h 30m
When
Sunday
Estimated price
$160 - $750
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbia, Sc to Winston Salem, Nc
Ave. Duration
5h 5m
Frequency
3 times a day
Estimated price
$21 - $55
Website
greyhound.com
Economy
$21 - $35
Flexible
$40 - $55
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2h 55m
Frequency
Once daily
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50

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