There are 6 ways to get from Charleston to Durham by car, train, bus or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Drive, train  •  8 h 30 min

  1. Drive from Charleston to Yemassee Amtrak
  2. Take the train from Yemassee Amtrak to Selma-Smithfield Amtrak
  3. Take the train from Selma-Smithfield Amtrak to Durham Amtrak

$80 - $189

Cheapest option

Bus  •  9 h 35 min

  1. Take the bus from Charleston, SC to Myrtle Beach Savannah
  2. Take the bus from Myrtle Beach to Raleigh, NC Savannah

$61 - $108

4 alternative options

Drive  •  5 h 1 min

  1. Drive from Charleston to Durham 305.8 miles

$29 - $45

Fly Charleston to Raleigh/Durham  •  6 h 23 min

  1. Fly from Charleston (CHS) to Raleigh/Durham (RDU) CHS - RDU

$139 - $631

Drive to Hilton Head, fly to Raleigh/Durham  •  7 h 23 min

  1. Drive from Charleston to Hilton Head
  2. Fly from Hilton Head (HHH) to Raleigh/Durham (RDU) HHH - RDU

$94 - $431

Fly Charleston to Charlotte, train  •  6 h 58 min

  1. Fly from Charleston (CHS) to Charlotte (CLT) CHS - CLT
  2. Take the train from Charlotte Amtrak to Durham Amtrak

$172 - $713

Questions & Answers

No, there is no direct bus from Charleston to Durham. However, there are services departing from Mary St / Meeting St and arriving at Durham, Nc via Charleston, SC, Myrtle Beach and Raleigh, Nc. The journey, including transfers, takes approximately 9 h 35 min.

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The distance between Charleston and Durham is 231 miles. The road distance is 305.8 miles.

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The best way to get from Charleston to Durham without a car is to bus which takes 9 h 35 min and costs .

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It takes approximately 8 h 30 min to get from Charleston to Durham, including transfers.

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Charleston to Durham bus services, operated by South Eastern Stages, depart from Charleston, SC station.

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The best way to get from Charleston to Durham is to bus which takes 9 h 35 min and costs . Alternatively, you can fly, which costs and takes 6 h 23 min.

Mode details

There is no direct flight from Charleston Airport to Raleigh/Durham Airport. The quickest flight takes 3 h 14 min and has one stopover.

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Charleston to Durham bus services, operated by South Eastern Stages, arrive at Raleigh, NC station.

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Yes, the driving distance between Charleston to Durham is 306 miles. It takes approximately 5 h 1 min to drive from Charleston to Durham.

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JetBlue Airways, Southwest Airlines, United Airlines and two other airlines offer flights from Charleston Airport to Raleigh/Durham Airport.

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Map of how to get from Charleston to Durham.
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  • Distance: 231.3 miles
  • Duration: 8 h 30 min

What companies run services between Charleston, SC, USA and Durham, NC, USA?

You can take a bus from Charleston to Durham via Dorchester Rd / Allen, Charleston, SC, Myrtle Beach, Raleigh, NC, and Raleigh, Nc in around 9 h 35 min. Alternatively, American Airlines, United Airlines and three other airlines fly from Charleston to Durham hourly.

Airlines
American Airlines
Website
aa.com
Flights from Charleston to Raleigh/Durham via Charlotte
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$110 - $600
Flights from Charleston to Raleigh/Durham via Reagan Washington
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$130 - $650
Flights from Hilton Head to Raleigh/Durham via Charlotte
Ave. Duration
3 h 46 min
When
Every day
Estimated price
$80 - $410
Flights from Hilton Head to Raleigh/Durham via Charlotte, Reagan Washington
Ave. Duration
7 h 2 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$95 - $440
Flights from Hilton Head to Raleigh/Durham via Charlotte, Pittsburgh
Ave. Duration
7 h 4 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$100 - $450
Flights from Charleston to Charlotte
Ave. Duration
1 h 11 min
When
Every day
Estimated price
$110 - $600
Delta
Website
delta.com
Flights from Charleston to Raleigh/Durham via Atlanta
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$110 - $600
United Airlines
Website
united.com
Flights from Charleston to Raleigh/Durham via Washington Dulles
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$130 - $650
Southwest Airlines
Website
southwest.com
Flights from Charleston to Raleigh/Durham via Baltimore
Ave. Duration
3 h 37 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $600
Flights from Charleston to Raleigh/Durham via Nashville
Ave. Duration
4 h 5 min
When
Saturday
Estimated price
$150 - $650
JetBlue Airways
Website
jetblue.com
Flights from Charleston to Raleigh/Durham via New York JFK
Ave. Duration
4 h 19 min
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$140 - $650
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Yemassee Amtrak to Selma-Smithfield Amtrak
Ave. Duration
4 h 44 min
Frequency
Once daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Train from Selma-Smithfield Amtrak to Durham Amtrak
Ave. Duration
1 h 23 min
Frequency
Once daily
Estimated price
$24 - $50
Website
amtrak.com
Coach Seat
$24 - $40
Flexi Coach Seat
$40 - $65
Business Coach Seat
$35 - $50
Room
$140 - $200
Train from Charlotte Amtrak to Durham Amtrak
Ave. Duration
2 h 31 min
Frequency
4 times a day
Estimated price
$35 - $85
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$60 - $90
Business Coach Seat
$55 - $85
Room
$180 - $250
Bus operators
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Charleston, SC to Myrtle Beach
Ave. Duration
2 h 15 min
Frequency
Once daily
Estimated price
$20 - $35
Schedules at
southeasternstages.com
Bus from Myrtle Beach to Raleigh, NC
Ave. Duration
4 h 15 min
Frequency
Once daily
Estimated price
$30 - $50
Schedules at
southeasternstages.com

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More Questions & Answers

There are 111+ hotels available in Durham. Prices start at $65 USD per night.

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The best way to get from Charleston to Charleston Airport is to Shuttle Bus which takes 30 min and costs .

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