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There are 8 ways to get from Chapel Hill to Knoxville by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  24h 15m

  1. Take the bus from Durham, NC to New York, NY Durham / ...
  2. Take the bus from New York, NY to Knoxville, TN

$178 - $283

Cheapest option

Bus via Durham - Hillsborough Rd at LaSalle St  •  38h 15m

  1. Take the bus from Durham - Hillsborough Rd at LaSalle St to New York Pandora Bus
  2. Take the bus from New York, NY to Knoxville Nyc

$126 - $128

6 alternative options

Bus, train  •  26h 55m

  1. Take the bus from N Columbia St at W Franklin St to Salisbury St at W Morgan St Crx
  2. Take the train from Raleigh Union Station to New York Penn Station
  3. Take the bus from New York, NY to Knoxville, TN

$198 - $448

Bus, train via Greensboro  •  41h 7m

  1. Take the bus from Columbia & Rosemary to Greensboro Depot 4
  2. Take the train from Greensboro Amtrak Station to New York Penn Station
  3. Take the bus from New York, NY to Knoxville Nyc

$140 - $274

Drive  •  5h 55m

  1. Drive from Chapel Hill to Knoxville 337.3 miles

$30 - $50

Fly from Raleigh/Durham  •  6h 13m

  1. Fly from Raleigh/Durham (RDU) to Knoxville (TYS) RDU - TYS

$229 - $396

Bus to Greensboro/High Point, fly  •  7h 10m

  1. Take the bus from Columbia & Rosemary to Coble Transportation Center
  2. Fly from Greensboro/High Point (GSO) to Knoxville (TYS) GSO - TYS

$230 - $976

Bus, bus to Fayetteville Municipal, fly  •  8h 22m

  1. Take the bus from N Columbia St at W Franklin St to GoRaleigh Station
  2. Take the bus from Raleigh, Nc to Fayetteville, Nc
  3. Fly from Fayetteville Municipal (FAY) to Knoxville (TYS) FAY - TYS

$297 - $1,313

Questions & Answers

The cheapest way to get from Chapel Hill to Knoxville is to drive which costs $30 - $50 and takes 5h 55m.

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The quickest way to get from Chapel Hill to Knoxville is to drive which costs $30 - $50 and takes 5h 55m.

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No, there is no direct bus from Chapel Hill to Knoxville. However, there are services departing from S Columbia St at Abernethy Hall and arriving at Cumberland Ave EB @ Poplar Pl via GoDurham Station, Durham - Hillsborough Rd at LaSalle St, New York, NY and Kingston Pike EB Mid-block just past Walker Springs. The journey, including transfers, takes approximately 38h 15m.

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The distance between Chapel Hill and Knoxville is 274 miles. The road distance is 337.3 miles.

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The best way to get from Chapel Hill to Knoxville without a car is to bus which takes 24h 15m and costs $170 - $290.

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It takes approximately 24h 15m to get from Chapel Hill to Knoxville, including transfers.

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Chapel Hill to Knoxville bus services, operated by EastWest Bus, depart from Durham - Hillsborough Rd at LaSalle St station.

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The best way to get from Chapel Hill to Knoxville is to bus which takes 24h 15m and costs $170 - $290. Alternatively, you can fly, which costs $220 - $400 and takes 6h 13m.

Mode details

There is no direct flight from Raleigh/Durham Airport to Knoxville Airport. The quickest flight takes 3h 29m and has one stopover.

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Chapel Hill to Knoxville bus services, operated by Wanda Coach, arrive at Knoxville station.

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Map of how to get from Chapel Hill to Knoxville.
Launch map view
  • Distance: 273.7 miles
  • Duration: 24h 15m

What companies run services between Chapel Hill, NC, USA and Knoxville, TN, USA?

You can take a bus from Chapel Hill to Knoxville via GoDurham Station, Durham, NC, New York, NY, Knoxville, TN, and Kingston Pike EB Mid-block just past Walker Springs in around 24h 15m. Alternatively, Delta, American Airlines and United Airlines fly from Chapel Hill to Knoxville hourly.

Airlines
Delta
Website
delta.com
Flights from Raleigh/Durham to Knoxville via Atlanta
Ave. Duration
3h 54m
When
Every day
Estimated price
$250 - $460
Flights from Raleigh/Durham to Knoxville via New York La Guardia
Ave. Duration
5h 21m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $460
Flights from Greensboro/High Point to Knoxville via Atlanta
Ave. Duration
3h 31m
When
Every day
Estimated price
$170 - $950
Flights from Greensboro/High Point to Knoxville via Detroit
Ave. Duration
4h 58m
When
Every day
Estimated price
$210 - $1,000
Flights from Greensboro/High Point to Knoxville via New York La Guardia
Ave. Duration
5h 18m
When
Monday to Friday
Estimated price
$220 - $1,100
Flights from Fayetteville Municipal to Knoxville via Atlanta
Ave. Duration
4h 12m
When
Every day
Estimated price
$220 - $1,200
American Airlines
Website
aa.com
Flights from Raleigh/Durham to Knoxville via Charlotte
Ave. Duration
3h 42m
When
Every day
Estimated price
$260 - $460
Flights from Raleigh/Durham to Knoxville via Chicago O'Hare
Ave. Duration
5h 2m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $460
Flights from Raleigh/Durham to Knoxville via New York La Guardia
Ave. Duration
5h 6m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $460
Flights from Raleigh/Durham to Knoxville via Philadelphia
Ave. Duration
5h 17m
When
Every day
Estimated price
$260 - $460
Flights from Greensboro/High Point to Knoxville via Charlotte
Ave. Duration
3h 53m
When
Every day
Estimated price
$170 - $900
Flights from Greensboro/High Point to Knoxville via Philadelphia
Ave. Duration
5h 19m
When
Every day
Estimated price
$220 - $1,100
Flights from Greensboro/High Point to Knoxville via New York La Guardia
Ave. Duration
5h 33m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,100
Flights from Greensboro/High Point to Knoxville via Reagan Washington
Ave. Duration
5h 48m
When
Every day
Estimated price
$200 - $1,000
Flights from Fayetteville Municipal to Knoxville via Charlotte
Ave. Duration
3h 51m
When
Every day
Estimated price
$210 - $1,200
United Airlines
Website
united.com
Flights from Raleigh/Durham to Knoxville via Washington Dulles
Ave. Duration
3h 56m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $750
Flights from Raleigh/Durham to Knoxville via Chicago O'Hare
Ave. Duration
4h 55m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $750
Flights from Greensboro/High Point to Knoxville via Washington Dulles
Ave. Duration
4h 19m
When
Every day
Estimated price
$220 - $1,100
Flights from Greensboro/High Point to Knoxville via Newark
Ave. Duration
5h 46m
When
Monday to Saturday
Estimated price
$250 - $1,100
Flights from Greensboro/High Point to Knoxville via Chicago O'Hare
Ave. Duration
6h 16m
When
Every day
Estimated price
$250 - $1,100
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Raleigh Union Station to New York Penn Station
Ave. Duration
10h 5m
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Train from Greensboro Amtrak Station to New York Penn Station
Ave. Duration
10h 2m
Frequency
Twice daily
Estimated price
$75 - $210
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$130 - $200
Business Coach Seat
$150 - $210
Room
$320 - $450
Bus operators
Wanda Coach
Phone
6466307186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from Durham, NC to New York, NY
Ave. Duration
8h 45m
Frequency
Hourly
Estimated price
$60
Schedules at
wandacoach.com
Bus from New York, NY to Knoxville
Ave. Duration
25h 30m
Frequency
6 times a week
Estimated price
$60
Schedules at
wandacoach.com
NYTN Bus
Website
nytnbus.com
Bus from New York, NY to Knoxville, TN
Ave. Duration
11h 30m
Frequency
Once daily
Estimated price
$100 - $200
Schedules at
nytnbus.com
Go Triangle
Phone
+1 919-485-7433
Email
customerservice@gotriangle.org
Website
gotriangle.org
Bus from N Columbia St at W Franklin St to Salisbury St at W Morgan St
Ave. Duration
1h 13m
Frequency
Every 3 hours
Estimated price
$2 - $3
Schedules at
gotriangle.org
Bus from N Columbia St at W Franklin St to GoRaleigh Station
Ave. Duration
1h 15m
Frequency
Every 3 hours
Estimated price
$2 - $3
Schedules at
gotriangle.org
EastWest Bus
Phone
4048498583
Website
eastwestbus.com
Bus from Durham - Hillsborough Rd at LaSalle St to New York
Ave. Duration
8h 20m
Frequency
Every 4 hours
Estimated price
$60
Schedules at
eastwestbus.com
Book at
eastwestbus.com
Pandora Bus
Website
pandorabus.com
Bus from Durham, NC - 3414 Hillsborough to New York, NY - 103 Canal St.
Ave. Duration
9h 15m
Frequency
Every 4 hours
Estimated price
$60
Schedules at
pandorabus.com
Book at
gotobus.com
PART NC
Phone
+1 336-662-0002
Website
partnc.org
Bus from Columbia & Rosemary to Greensboro Depot
Ave. Duration
1h 26m
Frequency
3 times a day
Estimated price
$3
Schedules at
partnc.org
Bus from Columbia & Rosemary to Coble Transportation Center
Ave. Duration
1h 29m
Frequency
Twice daily
Estimated price
$3
Schedules at
partnc.org
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Raleigh, Nc to Fayetteville, Nc
Ave. Duration
1h 5m
Frequency
Every 2 hours
Estimated price
$12 - $18
Website
greyhound.com
Economy
$12 - $18
Flexible
$30 - $45

Want to know more about travelling around United States

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More Questions & Answers

Yes, the driving distance between Chapel Hill to Knoxville is 337 miles. It takes approximately 5h 55m to drive from Chapel Hill to Knoxville.

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United Airlines, American Airlines and Delta offer flights from Raleigh/Durham Airport to Knoxville Airport.

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There are 107+ hotels available in Knoxville. Prices start at $55 USD per night.

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