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How to get fromCayce to Chicagoby plane, bus, train, bus (Flixbus) or car

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There are 9 ways to get from Cayce to Chicago by plane, bus, train, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Columbia to Chicago O'Hare International Airport

    best
    1. Fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD)plane plane CAE - ORD
    4h 23m
    $58–326

  2. Bus, train

    1. Take the bus from Columbia, SC to Camdenbus bus
    2. Take the bus from Camden to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    30h 51m
    $361–770

  3. Bus

    1. Take the bus from Columbia, SC to New York, NYbus bus Augusta
    2. Take the bus from New York City Chinatown to Chicago Bus Stationbus bus FlixBus N2640
    38h 41m
    $228–364

  4. Drive 764.9 mi

    1. Drive from Cayce to Chicagocar car 764.9 mi
    14h 10m
    $140–202

  5. Drive to Charlotte Douglas International Airport, fly to Chicago O'Hare International Airport

    1. Drive from Cayce to Charlotte-Airport-CLTcar car
    2. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    4h 48m
    $109–380

  6. Drive to Charleston International Airport, fly to Chicago Midway International Airport

    1. Drive from Cayce to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Chicago Midway International Airport (MDW)plane plane CHS - MDW
    4h 40m
    $106–502

  7. Fly Columbia to Chicago Midway International Airport

    1. Fly from Columbia (CAE) to Chicago Midway International Airport (MDW)plane plane CAE - MDW
    6h 4m
    $84–456

  8. Drive to Charlotte Douglas International Airport, fly to Chicago Midway International Airport

    1. Drive from Cayce to Charlotte-Airport-CLTcar car
    2. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    4h 30m
    $89–440

  9. Drive to Greenville–Spartanburg International Airport, fly to Chicago O'Hare International Airport

    1. Drive from Cayce to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Chicago O'Hare International Airport (ORD)plane plane GSP - ORD
    5h
    $86–432

Columbia (CAE) to Chicago O'Hare International Airport (ORD) flights

Calendar88Weekly Planes
Duration4h 1mAverage Duration
Ticket$58Cheapest Price
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Questions & Answers

What companies run services between Cayce, SC, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, you can take a bus from Charleston Hwy Across From Walmart to Chicago Bus Station via Sumter Laurel South, Broad Marley North, Columbia, SC, New York, NY, and New York City Chinatown in around 38h 41m.

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