From Cape Coral Parkway @ Vincennes Street line 30 bus to Bell Tower Shops @ Bell Tower Shops Avenue, line 50 bus to Fort Myers, FL - McDonalds, then bus to Tampa, FL - McDonalds. 4 h 49 min $36. From Forty-Seventh Terrace @ Vincennes Street line 70 bus to Ft Myers, FL then bus to Tampa, FL. 5 h 20 min $38. From Cape Coral drive to Tampa. 2 h 17 min $15.