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How to get fromCape Cod to San Diegoby bus, plane, train, bus (Greyhound, Flixbus, Amtrak) or car

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There are 8 ways to get from Cape Cod to San Diego by bus, plane, train, bus (Greyhound, Flixbus, Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to San Diego International Airport

    best
    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus
    2. Fly from Boston Logan Airport (BOS) to San Diego International Airport (SAN)planeBOS - SAN
    10h 41m
    $203–538

  2. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus
    2. Take the train from Boston to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain
    4. Take the train from Fullerton Amtrak Station to San Diegotrain
    3d 1h
    $362–1,121

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus
    2. Take the bus from Boston to Newark Penn Stationbus
    3. Take the bus from Newark Penn Station to St Louis Bus Stationbus
    4. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
    5. Take the bus from Los Angeles to San Diegobus
    3d 4h

  4. Drive 2,987.6 mi

    1. Drive from Cape Cod to San Diegocar2,987.6 mi
    2d 2h
    $546–788

  5. Fly Barnstable Municipal Airport to San Diego International Airport

    1. Fly from Barnstable Municipal Airport (HYA) to San Diego International Airport (SAN)planeHYA - SAN
    11h 17m
    $258–1,011

  6. Bus to Provincetown Municipal Airport, fly to San Diego International Airport

    1. Take the bus from Patriot Square, South Dennis to MacMillan Pier, Provincetownbus
    2. Fly from Provincetown Municipal Airport (PVC) to San Diego International Airport (SAN)planePVC - SAN
    16h 21m
    $231–914

  7. Bus, train to Theodore Francis Green State Airport, fly to San Diego International Airport

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus
    2. Take the train from Boston to Providencetrain
    3. Fly from Theodore Francis Green State Airport (PVD) to San Diego International Airport (SAN)planePVD - SAN
    14h 10m
    $382–1,250

  8. Bus to Boston Logan Airport, fly to Los Angeles International Airport, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus
    2. Fly from Boston Logan Airport (BOS) to Los Angeles International Airport (LAX)planeBOS - LAX
    3. Take the bus from LAX Terminal 3 Shared Rides Stop to San Diegobus
    14h 20m
    $216–553

Cape Cod to San Diego by bus and train

Calendar7Weekly Services
Duration3d 1hAverage Duration
Ticket$362Cheapest Price
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Questions & Answers

What companies run services between Cape Cod, MA, USA and San Diego, CA, USA?

You can take a bus from Town Hall Lawton Bus Shelter to San Diego via Hyannis Transportation Center, Boston, Bus Terminal South Station, Boston, Newark Penn Station, St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 3d 4h. Alternatively, American Airlines, Cape Air, and JetBlue Airways fly from Barnstable Municipal Airport (HYA) to San Diego International Airport (SAN) 5 times a day.

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