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How to get fromCape Cod to San Diegoby bus, plane, train, bus (Greyhound, Flixbus, Amtrak) or car

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There are 7 ways to get from Cape Cod to San Diego by bus, plane, train, bus (Greyhound, Flixbus, Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly

    best
    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to San Diego International Airport (SAN)plane plane BOS - SAN
    10h 15m
    $301–1,143
  2. Bus, train to Theodore Francis Green State Airport, fly

    cheapest
    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to San Diego International Airport (SAN)plane plane PVD - SAN
    14h 10m
    $219–909
  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d 1h
    $362–1,022
  4. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    5. Take the bus from Los Angeles to San Diegobus bus
    3d 3h
  5. Drive 2,987.7 mi

    1. Drive from Cape Cod to San Diegocar car 2,987.7 mi
    2d 2h
    $546–788
  6. Fly from Barnstable Municipal Airport

    1. Fly from Barnstable Municipal Airport (HYA) to San Diego International Airport (SAN)plane plane HYA - SAN
    10h 39m
    $386–1,606
  7. Bus to Provincetown Municipal Airport, fly

    1. Take the bus from Theophilus F. Smith Road to Race Point Beachbus bus
    2. Fly from Provincetown Municipal Airport (PVC) to San Diego International Airport (SAN)plane plane PVC - SAN
    11h 49m
    $276–1,106

Cape Cod to San Diego by bus and train

Calendar7Weekly Services
Duration3d 1hAverage Duration
Ticket$362Cheapest Price
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Questions & Answers

What companies run services between Cape Cod, MA, USA and San Diego, CA, USA?

You can take a bus from Town Hall Lawton Bus Shelter to San Diego via Hyannis Transportation Center, Boston, Bus Terminal South Station, Boston, Newark Penn Station, St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 3d 3h. Alternatively, American Airlines, Cape Air, and two other airlines fly from Barnstable Municipal Airport (HYA) to San Diego International Airport (SAN) 4 times a day.

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