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How to get fromCape Cod to Ithacaby bus (Flixbus), train, bus, car, plane, or taxi

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There are 10 ways to get from Cape Cod to Ithaca by bus (Flixbus), train, bus, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Hyannis to Bostonbus bus Bz 0947 / ...
    2. Take the bus from Boston to Ithacabus bus FlixBus 2691
    10h 24m
    $93–154

  2. Drive 393.8 mi

    cheapest
    1. Drive from Cape Cod to Ithacacar car 393.8 mi
    7h 23m
    $72–104

  3. Train, bus

    1. Take the train from Hyannis to South Stationtrain train
    2. Take the train from Boston to Utica Amtrak Stationtrain train
    3. Take the bus from Utica Bus Stop to Ithacabus bus
    14h 42m
    $144–295

  4. Fly Barnstable Municipal Airport to Syracuse Hancock International Airport, bus

    1. Fly from Barnstable Municipal Airport (HYA) to Syracuse Hancock International Airport (SYR)plane plane HYA - SYR
    2. Take the bus from Syracuse Bus Station to Ithacabus bus
    7h 36m
    $138–722

  5. Bus via New Haven

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Providence to New Havenbus bus
    3. Take the bus from New Haven, CT - Union Station to Ithaca, NY - West Ave across from Bakers Flagpolebus bus
    11h 50m
    $142–314

  6. Taxi to Provincetown Municipal Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the taxi from Cape Cod to Provincetown Municipal Airport (PVC)taxi taxi
    2. Fly from Provincetown Municipal Airport (PVC) to Syracuse Hancock International Airport (SYR)plane plane PVC - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    10h 28m
    $274–972

  7. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester to Ithacabus bus
    7h 30m
    $168–748

  8. Bus to Boston Logan Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    7h 33m
    $136–711

  9. Fly Barnstable Municipal Airport to Ithaca Tompkins Regional Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH)plane plane HYA - ITH
    8h 53m
    $81–390

  10. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    3. Take the bus from Buffalo Niagara International Airport to Ithacabus bus
    8h 55m
    $141–659

Barnstable Municipal Airport (HYA) to Syracuse Hancock International Airport (SYR) flights

Calendar24Weekly Planes
Duration5h 47mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

Map of how to get from Cape Cod to Ithaca.ExpandLaunch map view
  • Distance: 456.2 mi
  • Duration: 10h 24m

What companies run services between Cape Cod, MA, USA and Ithaca, NY, USA?

You can take a vehicle from Cape Cod to Ithaca via Hyannis and Boston in around 10h 24m. Alternatively, JetBlue Airways, Delta, and three other airlines fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH) 3 times a day.

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